RENBP cdna clone
RENBP cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature. [provided by RefSeq, Jul 2008]
Uniprot Description
RENBP: Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. Binds to renin forming a protein complex called high molecular weight (HMW) renin and inhibits renin activity. Belongs to the N-acylglucosamine 2-epimerase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Isomerase; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Inhibitor; EC 5.1.3.8
Chromosomal Location of Human Ortholog: Xq28
Cellular Component: cytosol
Molecular Function: endopeptidase inhibitor activity; N-acylglucosamine 2-epimerase activity
Biological Process: N-acetylglucosamine metabolic process; N-acetylneuraminate catabolic process; regulation of blood pressure; UDP-N-acetylglucosamine biosynthetic process
Research Articles on RENBP
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Product Notes
The RENBP renbp (Catalog #AAA1269229) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggagaaag agcgagagac tctgcaggcc tggaaggagc gcgtggggca ggagctggac cgcgtggtgg ctttctggat ggagcactcc cacgaccagg agcacggggg cttcttcacg tgccttggcc gcgaggggcg ggtgtatgat gacctcaagt atgtgtggct gcaggggagg caggtatgga tgtattgtcg cctgtaccgc actttcgagc gcttccgcca tgctcagctt ctggacgcag caaaagcagg tggtgagttc ttgctgcggt atgcccgggt ggcacctcct ggcaagaagt gtgcctttgt gctgactcgg gacggccgcc cggtcaaggt gcagcgaacc atcttcagtg agtgtttcta caccatggcc atgaacgagc tgtggagagc cacaggggaa gtgcggtacc agacggaagc ggtggagatg atggatcaga tcgtccactg ggtgcaggag gacgcgtcgg gactgggccg gccccagctc cagggggccc cggctgcgga gcccatggcg gtgcccatga tgctactgaa cctggtggag cagctcgggg aggcagatga ggagctggcg ggcaaatacg cagagctggg ggactggtgc gcccggagga ttctgcagca cgtgcagagg gatggacaag ctgtgccgga gaatgtgtca gagggtggca aggaacttcc tggctgcctg gggagacagc agaacccagg ccacacgctg gaagccggct ggtttctgct ccgtcattgc attcggaaag gcgaccccga acttcgagcc cacgtgattg acaagttcct attgttgccc ttccactccg gatgggaccc tgaccacgga ggcctctttt acttccagga tgctgataac ttctgcccca cccagctgga gtgggccatg aagctctggt ggccacacag tgaagccatg attgccttcc tcatgggtta cagtgacagt ggggaccctg tgctgctgcg cctcttctac caagtggctg agtacacctt ccgccagttt cgcgatcccg agtacgggga atggtttggc tacctgagcc gagagggcaa ggtggccctc tccatcaagg gaggtccttt caaaggctgc ttccacgtgc cgcggtgcct agccatgtgc gaggagatgc tgggcgccct gctgagccgc cccgcccccg ccccctcccc cgcccccacc cccgcctgcc gaggcgcgga ataa. It is sometimes possible for the material contained within the vial of "RENBP, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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