PPFIA1 cdna clone

PPFIA1 cDNA Clone

Gene Names

PPFIA1; LIP1; LIP.1; LIPRIN

Synonyms

PPFIA1; PPFIA1 cDNA Clone; PPFIA1 cdna clone

Ordering
Cat. Num. AAA1270930 For Research Use Only!

Sequence

atgatgtgcgaggtgatgccgaccatcagcgaagcagaaggcccccctggaggaggtggaggccatggttccggctccccttcacagccagatgcagattcacattttgaacagttgatggtctccatgctagaagaaagggaccgccttcttgatacactgagagagactcaagaaacgctggccttaacccaggggaagttacacgaggttggtcatgaaagagattccttgcagagacagctcaacacagcacttccacaggagttcgcagcacttactaaagaactcaatgtatgcagggaacagctccttgaaagggaagaagaaattgctgaactgaaagcagaaaggaataacaccaggctgctgttagagcatttggaatgccttgtctccaggcatgagcggtctcttaggatgaccgtggtgaagagacaagcgcagtctccagcaggcgtgtccagcgaagtggaagtgctgaaagcactgaagtccttatttgaacaccacaaagctctggatgaaaaggtgagagagcgattacgagtagcacttgaaagatgtagtttgttagaagaggaattaggtgccacacacaaagagctaatgattcttaaagaacagaataatcagaaaaaaactctaacagatggagtgctggacataaaccatgaacaagaaaatacaccaagcacgagtggaaagagatcttctgatggttctttaagccacgaggaagaccttgctaaagtaattgagctccaagaaatcataagtaagcagtcaagggaacagagccaaatgaaagaacgcctggcttccctttccagtcatgtgacagaactggaagaggatctggacacggctagaaaagatctcatcaaatctgaagaaatgaacacaaaattgcaacgagatgtccgtgaagccatggcccaaaaggaagatatggaagagagaatcactactcttgaaaaacgctacctcgctgcacagcgtgaagccacatctgtgcatgacctcaatgataaacttgaaaatgaaattgcaaataaagattctatgcatcgacagactgaagataaaaaccgccagttacaggagcgcttggaattggcagagcaaaagctgcaacagacactgaggaaggcagagacgctcccggaggtggaggcggagctggcccagagggtggcagcgctttccaaggctgaagagagacacggcaacattgaagaaaggttacgacagatggaagcacagttggaggagaagaatcaagaactgcagcgggcaaggcaaagagaaaaaatgaacgaagaacataataaacgtttatcagacactgttgacaagctgctttcagaatctaatgagaggcttcaacttcatcttaaagagagaatggctgctttggaagataagaactctcttttaagagaagttgaaagtgcaaaaaagcagttagaaggaacacaacacgataaggatcagcttgtcctaaacattgaagcactgagggctgaactagaccacatgagactaagaggtgcttcacttcatcatggccgaccccacttgggcagtgtcccagatttcaggttccccatggcagatggccacacagactcctacagcaccagtgcagtgctgcggcgcacacagaaaggccggctggcagccctgcgagatgagccttccaaggtacaaactcttaatgagcaggattgggaacgtgcccagcaagctagtgtcttggcaaatgtagcacaagcattcgagagtgatgctgacgtgtctgatggtgaagatgacagggacactctcctcagctcagttgacctgctatcgcccagcgggcaggccgacgcgcacacactagccatgatgcttcaggagcagctggacgccatcaacaaagagatcaggttgattcaggaagaaaaagaaaatacagagcagcgggcagaggagattgaaagtcgagttggcagtggaagtctagacaatcttggtcgttttagatcaatgagctccattcccccctaccctgcttcctcgcttgctagctcctcccctccgggcagtgggcgctccaccccacgaaggatccctcacagcccagctcgggaagtggacagactgggcgtcatgacccttttgccaccttccagagaagaggtacgagatgacaagacaaccataaagtgtgaaacctccccgccttcctccccgagagcccttcggttagaccggctgcacaaaggggcgctgcacaccgttagccacgaggacatcagggacataaggaactccacaggctcccaggatggtcccgtgagcaaccccagcagtagcaacagtagccaggactcgctccacaaagccccaaagaagaaaggcattaagtcctccattggccgcttgtttggcaagaaagaaaagggccgacctggacaaactggcaaagaagcattaggacaagctggtgtttccgagacggataactcatctcaggatgccttgggacttagcaaattggggggacaggctgaaaaaaatcgtaaacttcaaaaaaagcatgaattgctgggggaagcccggagacaaggtttaccttttgcccaatgggacgggccaacggttgtggtctggctagagctctgggttgggatgccagcctggtatgtggctgcctgccgagcaaacgtgaaaagcggggccatcatgtcggccctgtccgacacagagatccagcgtgagattggcatcagcaaccccctgcacaggctgaagctgaggctggccatccaggagatcatgtcgctgaccagcccgtctgccccgcccacatctagaacgacactcgcctatggggacatgaaccacgagtggatcggcaacgagtggctccccagcctgggcctcccccagtaccgcagctacttcatggagtgccttgtagacgccaggatgctggaccacttgaccaagaaagaccttcgagggcagctgaaaatggtcgacagttttcacagaaacagtttccagtgtggaattatgtgcctgagaaggttaaattatgaccggaaagaactggaaagaaaaagagaagaaagtcagagtgaaataaaagacgtgcttgtttggagcaatgatcgagtgattcgctggatcctgtcaattggccttaaagaatatgcaaacaatcttatagagagtggtgttcacggagcacttctggccttagatgaaaccttcgacttcagtgcactggcactgctgttacagatcccaacgcagaacacacaggctcgtgctgtcttggaaagagaatttaacaaccttttggtcatggggactgatagaaggtttgatgaagatgatgataaaagctttaggagagcaccttcatggagaaaaaagtttagaccaaaggacattcgtggcttagctgctgggtcagcagagactctccctgcaaacttccgggtgacttcttctatgtcttccccctctatgcagccaaagaagatgcagatggacggcaatgtatcaggaacacagaggttggattctgctacagtcaggacttactcctgctaa

Sequence Length

3609

Vector

Please Inquire

NCBI and Uniprot Product Information

NCBI GI #

21707844

NCBI GeneID

8500

Molecular Weight

133,970 Da

NCBI Official Full Name

Homo sapiens protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1, mRNA

NCBI Official Synonym Full Names

PTPRF interacting protein alpha 1

NCBI Official Symbol

PPFIA1

NCBI Official Synonym Symbols

LIP1; LIP.1; LIPRIN

NCBI Protein Information

liprin-alpha-1

UniProt Protein Name

Liprin-alpha-1

Protein Family

Liprin

UniProt Gene Name

PPFIA1

UniProt Synonym Gene Names

LIP1; LIP-1; PTPRF-interacting protein alpha-1

UniProt Entry Name

LIPA1_HUMAN

NCBI Description

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Uniprot Description

liprin alpha 1: a ubiqutous member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Two alternatively spliced isoforms have been described.

Protein type: Motility/polarity/chemotaxis; Cell adhesion

Chromosomal Location of Human Ortholog: 11q13.3

Cellular Component: cytoplasm; cytosol; focal adhesion; presynaptic active zone

Molecular Function: protein binding; signal transducer activity

Biological Process: cell-matrix adhesion; glutamate secretion; negative regulation of stress fiber formation; neurotransmitter secretion; signal transduction

Research Articles on PPFIA1

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Product Notes

The PPFIA1 ppfia1 (Catalog #AAA1270930) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgatgtgcg aggtgatgcc gaccatcagc gaagcagaag gcccccctgg aggaggtgga ggccatggtt ccggctcccc ttcacagcca gatgcagatt cacattttga acagttgatg gtctccatgc tagaagaaag ggaccgcctt cttgatacac tgagagagac tcaagaaacg ctggccttaa cccaggggaa gttacacgag gttggtcatg aaagagattc cttgcagaga cagctcaaca cagcacttcc acaggagttc gcagcactta ctaaagaact caatgtatgc agggaacagc tccttgaaag ggaagaagaa attgctgaac tgaaagcaga aaggaataac accaggctgc tgttagagca tttggaatgc cttgtctcca ggcatgagcg gtctcttagg atgaccgtgg tgaagagaca agcgcagtct ccagcaggcg tgtccagcga agtggaagtg ctgaaagcac tgaagtcctt atttgaacac cacaaagctc tggatgaaaa ggtgagagag cgattacgag tagcacttga aagatgtagt ttgttagaag aggaattagg tgccacacac aaagagctaa tgattcttaa agaacagaat aatcagaaaa aaactctaac agatggagtg ctggacataa accatgaaca agaaaataca ccaagcacga gtggaaagag atcttctgat ggttctttaa gccacgagga agaccttgct aaagtaattg agctccaaga aatcataagt aagcagtcaa gggaacagag ccaaatgaaa gaacgcctgg cttccctttc cagtcatgtg acagaactgg aagaggatct ggacacggct agaaaagatc tcatcaaatc tgaagaaatg aacacaaaat tgcaacgaga tgtccgtgaa gccatggccc aaaaggaaga tatggaagag agaatcacta ctcttgaaaa acgctacctc gctgcacagc gtgaagccac atctgtgcat gacctcaatg ataaacttga aaatgaaatt gcaaataaag attctatgca tcgacagact gaagataaaa accgccagtt acaggagcgc ttggaattgg cagagcaaaa gctgcaacag acactgagga aggcagagac gctcccggag gtggaggcgg agctggccca gagggtggca gcgctttcca aggctgaaga gagacacggc aacattgaag aaaggttacg acagatggaa gcacagttgg aggagaagaa tcaagaactg cagcgggcaa ggcaaagaga aaaaatgaac gaagaacata ataaacgttt atcagacact gttgacaagc tgctttcaga atctaatgag aggcttcaac ttcatcttaa agagagaatg gctgctttgg aagataagaa ctctctttta agagaagttg aaagtgcaaa aaagcagtta gaaggaacac aacacgataa ggatcagctt gtcctaaaca ttgaagcact gagggctgaa ctagaccaca tgagactaag aggtgcttca cttcatcatg gccgacccca cttgggcagt gtcccagatt tcaggttccc catggcagat ggccacacag actcctacag caccagtgca gtgctgcggc gcacacagaa aggccggctg gcagccctgc gagatgagcc ttccaaggta caaactctta atgagcagga ttgggaacgt gcccagcaag ctagtgtctt ggcaaatgta gcacaagcat tcgagagtga tgctgacgtg tctgatggtg aagatgacag ggacactctc ctcagctcag ttgacctgct atcgcccagc gggcaggccg acgcgcacac actagccatg atgcttcagg agcagctgga cgccatcaac aaagagatca ggttgattca ggaagaaaaa gaaaatacag agcagcgggc agaggagatt gaaagtcgag ttggcagtgg aagtctagac aatcttggtc gttttagatc aatgagctcc attcccccct accctgcttc ctcgcttgct agctcctccc ctccgggcag tgggcgctcc accccacgaa ggatccctca cagcccagct cgggaagtgg acagactggg cgtcatgacc cttttgccac cttccagaga agaggtacga gatgacaaga caaccataaa gtgtgaaacc tccccgcctt cctccccgag agcccttcgg ttagaccggc tgcacaaagg ggcgctgcac accgttagcc acgaggacat cagggacata aggaactcca caggctccca ggatggtccc gtgagcaacc ccagcagtag caacagtagc caggactcgc tccacaaagc cccaaagaag aaaggcatta agtcctccat tggccgcttg tttggcaaga aagaaaaggg ccgacctgga caaactggca aagaagcatt aggacaagct ggtgtttccg agacggataa ctcatctcag gatgccttgg gacttagcaa attgggggga caggctgaaa aaaatcgtaa acttcaaaaa aagcatgaat tgctggggga agcccggaga caaggtttac cttttgccca atgggacggg ccaacggttg tggtctggct agagctctgg gttgggatgc cagcctggta tgtggctgcc tgccgagcaa acgtgaaaag cggggccatc atgtcggccc tgtccgacac agagatccag cgtgagattg gcatcagcaa ccccctgcac aggctgaagc tgaggctggc catccaggag atcatgtcgc tgaccagccc gtctgccccg cccacatcta gaacgacact cgcctatggg gacatgaacc acgagtggat cggcaacgag tggctcccca gcctgggcct cccccagtac cgcagctact tcatggagtg ccttgtagac gccaggatgc tggaccactt gaccaagaaa gaccttcgag ggcagctgaa aatggtcgac agttttcaca gaaacagttt ccagtgtgga attatgtgcc tgagaaggtt aaattatgac cggaaagaac tggaaagaaa aagagaagaa agtcagagtg aaataaaaga cgtgcttgtt tggagcaatg atcgagtgat tcgctggatc ctgtcaattg gccttaaaga atatgcaaac aatcttatag agagtggtgt tcacggagca cttctggcct tagatgaaac cttcgacttc agtgcactgg cactgctgtt acagatccca acgcagaaca cacaggctcg tgctgtcttg gaaagagaat ttaacaacct tttggtcatg gggactgata gaaggtttga tgaagatgat gataaaagct ttaggagagc accttcatgg agaaaaaagt ttagaccaaa ggacattcgt ggcttagctg ctgggtcagc agagactctc cctgcaaact tccgggtgac ttcttctatg tcttccccct ctatgcagcc aaagaagatg cagatggacg gcaatgtatc aggaacacag aggttggatt ctgctacagt caggacttac tcctgctaa. It is sometimes possible for the material contained within the vial of "PPFIA1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

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PPFIA1 cdna clone