PMPCB cdna clone

PMPCB cDNA Clone

Cat. Num. AAA1269567

• Gene Names: PMPCB; MPPB; P-52; MPP11; MPPP52; Beta-MPP
• Synonyms: PMPCB; PMPCB cDNA Clone; PMPCB cdna clone

• Sequence: atggctttcaagggcaccaagaagagatcccagttagatctggaacttgagattgaaaatatgggtgctcatctcaatgcctatacctccagagagcagactgtatactatgccaaagcattctctaaagacttgccaagagctgtagaaattcttgctgatataatacaaaacagcacattgggagaagcagagattgaacgtgagcgtggagtaatccttagagagatgcaggaagttgaaaccaatttacaagaagttgtttttgattatcttcatgccacagcttatcaaaatactgcacttggacggacaattttgggaccaactgaaaatatcaaatctataagtcgtaaggacttagtggattatataaccacacattataaggggccaagaatagtgcttgctgctgctggaggtgtttcccatgatgaattgcttgacttagcaaagtttcatttcggtgactctttatgcacacacaaaggagaaataccagctctgcctccctgcaaattcacaggaagtgagattcgtgtgagggatgacaagatgcctttggcgcaccttgcaatagctgttgaagctgttggttgggcacatccagatacaatctgtctcatggttgcaaacacgctgattggcaactgggatcgctcttttgggggaggaatgaatttatctagcaagctggcccagctcacttgtcatggcaatctttgccatagctttcagtctttcaacacttcctacacagatacaggattatggggactgtatatggtttgtgaatcatccactgttgcagacatgctacatgttgttcaaaaagaatggatgcgactctgtacaagtgtcacagaaagtgaggttgcacgagccagaaatcttctgaaaacaaacatgttgttgcagcttgatggttcaactccaatttgtgaagatattggtaggcaaatgttatgctataatagaaggattcccatccctgagcttgaagcaagaattgatgctgtgaatgctgagacaattcgagaagtatgtaccaaatacatttataataggagtccagctattgctgctgttggtcccattaagcaactaccagattttaaacagatacgcagtaacatgtgttggcttcgtgattaa
• Sequence Length: 1155

• Vector: pENTR223.1 or pUC
• Clone Sequence Report: Provided with product shipment

NCBI and Uniprot Product Information

• NCBI GI #: 40226468
• NCBI GeneID: 9512
• Molecular Weight: 54,366 Da
• NCBI Official Full Name: Homo sapiens peptidase (mitochondrial processing) beta, mRNA
• NCBI Official Synonym Full Names: peptidase, mitochondrial processing beta subunit
• NCBI Official Symbol: PMPCB
• NCBI Official Synonym Symbols: MPPB; P-52; MPP11; MPPP52; Beta-MPP
• NCBI Protein Information: mitochondrial-processing peptidase subunit beta
• UniProt Protein Name: Mitochondrial-processing peptidase subunit beta
• UniProt Gene Name: PMPCB
• UniProt Synonym Gene Names: MPPB
• UniProt Entry Name: MPPB_HUMAN

NCBI Description

This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex. [provided by RefSeq, Jul 2008]

Uniprot Description

PMPCB: Cleaves presequences (transit peptides) from mitochondrial protein precursors. Belongs to the peptidase M16 family.

Protein type: Protease; Mitochondrial; EC 3.4.24.64

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: mitochondrial respiratory chain complex III

Molecular Function: metalloendopeptidase activity; zinc ion binding

Biological Process: aerobic respiration; mitochondrial electron transport, ubiquinol to cytochrome c; protein processing