PIGK cdna clone
PIGK cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the cysteine protease family C13 that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is a member of the multisubunit enzyme, GPI transamidase and is thought to be its enzymatic component. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. [provided by RefSeq, Jul 2008]
Uniprot Description
PIGK: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
Protein type: EC 3.-.-.-; Endoplasmic reticulum; Protease; Glycan Metabolism - glycosylphosphatidylinositol (GPI)-anchor biosynthesis; Membrane protein, integral
Chromosomal Location of Human Ortholog: 1p31.1
Cellular Component: endoplasmic reticulum membrane; GPI-anchor transamidase complex; membrane
Molecular Function: GPI-anchor transamidase activity; protein binding; protein disulfide isomerase activity
Biological Process: attachment of GPI anchor to protein
Research Articles on PIGK
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Product Notes
The PIGK pigk (Catalog #AAA1275185) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggccgtca ccgacagcct cagccgggct gcgactgtct tggcaactgt gttgctcttg tccttcggca gcgtggccgc tagtcatatc gaggatcaag cagaacaatt ctttagaagt ggccatacaa acaactgggc tgttctggtg tgtacatccc gattctggtt taattatcga catgttgcaa ataccctttc tgtttataga agtgtcaaga ggctaggtat tcctgacagt cacattgtcc taatgcttgc agatgatatg gcctgtaatc ctagaaatcc caaaccagct acagtgttta gtcacaagaa tatggaacta aatgtgtatg gagatgatgt ggaagtggat tatagaagtt atgaggtaac tgtggagaat tttttacggg tattaactgg ggggatccca cctagtactc ctcggtcaaa acgtcttctt tctgatgaca gaagcaatat tctaatttat atgacagggc atggtggaaa tggtttctta aaatttcaag attctgaaga aattaccaac atagaactcg cggatgcttt tgaacaaatg tggcagaaaa gacgctacaa tgagctactg tttattattg atacttgcca aggagcatcc atgtatgaac gattttattc tcctaacata atggctctag ctagtagtca agtgggagaa gattcactct cgcatcaacc tgatcctgca attggagtcc atcttatgga tagatacaca ttttatgtct tggaattttt ggaagaaatt aacccagcta gccaaactaa tatgaatgac ctttttcagg tatgtcccaa aagtctgtgt gtgtctactc ctggacatcg cactgatctt tttcagaggg atcctaaaaa tgtactgata actgatttct ttggaagtgt acggaaagtg gaaattacaa cagagactat taaattgcaa caggattcag aaatcatgga aagcaggtat tcatcttaa. It is sometimes possible for the material contained within the vial of "PIGK, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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