PAEP cdna clone
PAEP cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Uniprot Description
PAEP: This protein is, quantitatively, the main protein synthesized and secreted in the endometrium from mid-luteal phase of the menstrual cycle and during the first semester of pregnancy. Belongs to the calycin superfamily. Lipocalin family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 9q34
Molecular Function: protein binding
Biological Process: apoptosis; multicellular organismal development; positive regulation of granulocyte macrophage colony-stimulating factor production
Research Articles on PAEP
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Product Notes
The PAEP paep (Catalog #AAA1268279) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgctgtgcc tcctgctcac cctgggcgtg gccctggtct gtggtgtccc ggccatggac atcccccaga ccaagcagga cctggagctc ccaaagttgg cagggacctg gcactccatg gccatggcga ccaacaacat ctccctcatg gcgacactga aggcccctct gagggtccac atcacctcac tgttgcccac ccccgaggac aacctggaga tcgttctgca cagatgggag aacaacagct gtgttgagaa gaaggtcctt ggagagaaga ctgagaatcc aaagaagttc aagatcaact atacggtggc gaacgaggcc acgctgctcg atactgacta cgacaatttc ctgtttctct gcctacagga caccaccacc cccatccaga gcatgatgtg ccagtacctg gccagagtcc tggtggagga cgatgagatc atgcagggat tcatcagggc tttcaggccc ctgcccaggc acctatggta cttgctggac ttgaaacaga tggaagagcc gtgccgtttc tag. It is sometimes possible for the material contained within the vial of "PAEP, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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