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NRP2 cdna clone

NRP2 cDNA Clone

Gene Names
NRP2; NP2; NPN2; PRO2714; VEGF165R2
Synonyms
NRP2; NRP2 cDNA Clone; NRP2 cdna clone
Ordering
For Research Use Only!
Sequence
atggatatgtttcctctcacctgggttttcttagccctctacttttcaagacaccaagtgagaggccaaccagacccaccgtgcggaggtcgtttgaattccaaagatgctggctatatcacctctcccggttacccccaggactacccctcccaccagaactgcgagtggattgtttacgcccccgaacccaaccagaagattgtcctcaacttcaaccctcactttgaaatcgagaagcacgactgcaagtatgactttatcgagattcgggatggggacagtgaatccgcagacctcctgggcaaacactgtgggaacatcgccccgcccaccatcatctcctcgggctccatgctctacatcaagttcacctccgactacgcccggcagggggcaggcttctctctgcgctacgagatcttcaagacaggctctgaagattgctcaaaaaacttcacaagccccaacgggaccatcgaatctcctgggtttcctgagaagtatccacacaacttggactgcacctttaccatcctggccaaacccaagatggagatcatcctgcagttcctgatctttgacctggagcatgaccctttgcaggtgggagagggggactgcaagtacgattggctggacatctgggatggcattccacatgttggccccctgattggcaagtactgtgggaccaaaacaccctctgaacttcgttcatcgacggggatcctctccctgacctttcacacggacatggcggtggccaaggatggcttctctgcgcgttactacctggtccaccaagagccactagagaactttcagtgcaatgttcctctgggcatggagtctggccggattgctaatgaacagatcagtgcctcatctacctactctgatgggaggtggacccctcaacaaagccggctccatggtgatgacaatggctggacccccaacttggattccaacaaggagtatctccaggtggacctgcgctttttaaccatgctcacggccatcgcaacacagggagcgatttccagggaaacacagaatggctactatgtcaaatcctacaagctggaagtcagcactaatggagaggactggatggtgtaccggcatggcaaaaaccacaaggtatttcaagccaacaacgatgcaactgaggtggttctgaacaagctccacgctccactgctgacaaggtttgttagaatccgccctcagacctggcactcaggtatcgccctccggctggagctcttcggctgccgggtcacagatgctccctgctccaacatgctggggatgctctcaggcctcattgcagactcccagatctccgcctcttccacccaggaatacctctggagccccagtgcagcccgcctggtcagcagccgctcgggctggttccctcgaatccctcaggcccagcccggtgaggagtggcttcaggtagatctgggaacacccaagacagtgaaaggtgtcatcatccagggagcccgcggaggagacagtatcactgctgtggaagccagagcatttgtgcgcaagttcaaagtctcctacagcctaaacggcaaggactgggaatacattcaggaccccaggacccagcagccaaagctgttcgaagggaacatgcactatgacacccctgacatccgaaggtttgaccccattccggcacagtatgtgcgggtatacccggagaggtggtcgccggcggggattgggatgcggctggaggtgctgggctgtgactggacagactccaagcccacggtagagacgctgggacccactgtgaagagcgaagagacaaccaccccctaccccaccgaagaggaggccacagagtgtggggagaactgcagctttgaggatgacaaagatttgcagctcccttcgggattcaattgcaacttcgatttcctcgaggagccctgtggttggatgtatgaccatgccaagtggctccggaccacctgggccagcagctccagcccaaacgaccggacgtttccagatgacaggaatttcttgcggctgcagagtgacagccagagagagggccagtatgcccggctcatcagcccccctgtccacctgccccgaagcccggtgtgcatggagttccagtaccaggccacgggcggccgcggggtggcgctgcaggtggtgcgggaagccagccaggagagcaagttgctgtgggtcatccgtgaggaccagggcggcgagtggaagcacgggcggatcatcctgcccagctacgacatggagtaccagattgtgttcgagggagtgatagggaaaggacgttccggagagattgccattgatgacattcggataagcactgatgtcccactggagaactgcatggaacccatctcggcttttgcagtggacatcccagaaatacatgagagagaaggatatgaagatgaaattgatgatgaatacgaggtggactggagcaattcttcttctgcaacctcagggtctggcgccccctcgaccgacaaagaaaagagctggctgtacaccctggatcccatcctcatcaccatcatcgccatgagctcactgggcgtcctcctgggggccacctgtgcaggcctcctgctctactgcacctgttcctactcgggcctgagctcccgaagctgcaccacactggagaactacaacttcgagctctacgatggccttaagcacaaggtcaagatgaaccaccaaaagtgctgctccgaggcatga
Sequence Length
2781
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
62,458 Da
NCBI Official Full Name
Homo sapiens neuropilin 2, mRNA
NCBI Official Synonym Full Names
neuropilin 2
NCBI Official Symbol
NRP2
NCBI Official Synonym Symbols
NP2; NPN2; PRO2714; VEGF165R2
NCBI Protein Information
neuropilin-2
UniProt Protein Name
Neuropilin-2
Protein Family
UniProt Gene Name
NRP2
UniProt Synonym Gene Names
VEGF165R2
UniProt Entry Name
NRP2_HUMAN

NCBI Description

This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

NRP2: High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. Heterodimer with NRP1. Binds PLXNB1. Belongs to the neuropilin family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Receptor, misc.

Chromosomal Location of Human Ortholog: 2q33.3

Cellular Component: membrane; plasma membrane

Molecular Function: growth factor binding; receptor activity

Biological Process: axon extension involved in axon guidance; nerve development; positive regulation of endothelial cell proliferation; vascular endothelial growth factor receptor signaling pathway

Research Articles on NRP2

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Product Notes

The NRP2 nrp2 (Catalog #AAA1274729) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggatatgt ttcctctcac ctgggttttc ttagccctct acttttcaag acaccaagtg agaggccaac cagacccacc gtgcggaggt cgtttgaatt ccaaagatgc tggctatatc acctctcccg gttaccccca ggactacccc tcccaccaga actgcgagtg gattgtttac gcccccgaac ccaaccagaa gattgtcctc aacttcaacc ctcactttga aatcgagaag cacgactgca agtatgactt tatcgagatt cgggatgggg acagtgaatc cgcagacctc ctgggcaaac actgtgggaa catcgccccg cccaccatca tctcctcggg ctccatgctc tacatcaagt tcacctccga ctacgcccgg cagggggcag gcttctctct gcgctacgag atcttcaaga caggctctga agattgctca aaaaacttca caagccccaa cgggaccatc gaatctcctg ggtttcctga gaagtatcca cacaacttgg actgcacctt taccatcctg gccaaaccca agatggagat catcctgcag ttcctgatct ttgacctgga gcatgaccct ttgcaggtgg gagaggggga ctgcaagtac gattggctgg acatctggga tggcattcca catgttggcc ccctgattgg caagtactgt gggaccaaaa caccctctga acttcgttca tcgacgggga tcctctccct gacctttcac acggacatgg cggtggccaa ggatggcttc tctgcgcgtt actacctggt ccaccaagag ccactagaga actttcagtg caatgttcct ctgggcatgg agtctggccg gattgctaat gaacagatca gtgcctcatc tacctactct gatgggaggt ggacccctca acaaagccgg ctccatggtg atgacaatgg ctggaccccc aacttggatt ccaacaagga gtatctccag gtggacctgc gctttttaac catgctcacg gccatcgcaa cacagggagc gatttccagg gaaacacaga atggctacta tgtcaaatcc tacaagctgg aagtcagcac taatggagag gactggatgg tgtaccggca tggcaaaaac cacaaggtat ttcaagccaa caacgatgca actgaggtgg ttctgaacaa gctccacgct ccactgctga caaggtttgt tagaatccgc cctcagacct ggcactcagg tatcgccctc cggctggagc tcttcggctg ccgggtcaca gatgctccct gctccaacat gctggggatg ctctcaggcc tcattgcaga ctcccagatc tccgcctctt ccacccagga atacctctgg agccccagtg cagcccgcct ggtcagcagc cgctcgggct ggttccctcg aatccctcag gcccagcccg gtgaggagtg gcttcaggta gatctgggaa cacccaagac agtgaaaggt gtcatcatcc agggagcccg cggaggagac agtatcactg ctgtggaagc cagagcattt gtgcgcaagt tcaaagtctc ctacagccta aacggcaagg actgggaata cattcaggac cccaggaccc agcagccaaa gctgttcgaa gggaacatgc actatgacac ccctgacatc cgaaggtttg accccattcc ggcacagtat gtgcgggtat acccggagag gtggtcgccg gcggggattg ggatgcggct ggaggtgctg ggctgtgact ggacagactc caagcccacg gtagagacgc tgggacccac tgtgaagagc gaagagacaa ccacccccta ccccaccgaa gaggaggcca cagagtgtgg ggagaactgc agctttgagg atgacaaaga tttgcagctc ccttcgggat tcaattgcaa cttcgatttc ctcgaggagc cctgtggttg gatgtatgac catgccaagt ggctccggac cacctgggcc agcagctcca gcccaaacga ccggacgttt ccagatgaca ggaatttctt gcggctgcag agtgacagcc agagagaggg ccagtatgcc cggctcatca gcccccctgt ccacctgccc cgaagcccgg tgtgcatgga gttccagtac caggccacgg gcggccgcgg ggtggcgctg caggtggtgc gggaagccag ccaggagagc aagttgctgt gggtcatccg tgaggaccag ggcggcgagt ggaagcacgg gcggatcatc ctgcccagct acgacatgga gtaccagatt gtgttcgagg gagtgatagg gaaaggacgt tccggagaga ttgccattga tgacattcgg ataagcactg atgtcccact ggagaactgc atggaaccca tctcggcttt tgcagtggac atcccagaaa tacatgagag agaaggatat gaagatgaaa ttgatgatga atacgaggtg gactggagca attcttcttc tgcaacctca gggtctggcg ccccctcgac cgacaaagaa aagagctggc tgtacaccct ggatcccatc ctcatcacca tcatcgccat gagctcactg ggcgtcctcc tgggggccac ctgtgcaggc ctcctgctct actgcacctg ttcctactcg ggcctgagct cccgaagctg caccacactg gagaactaca acttcgagct ctacgatggc cttaagcaca aggtcaagat gaaccaccaa aagtgctgct ccgaggcatg a. It is sometimes possible for the material contained within the vial of "NRP2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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