NFYB cdna clone
NFYB
Translation Sequence: MTMDGDSSTT DASQLGISAD YIGGSHYVIQ PHDDTEDSMN DHEDTNGSKE SFREQDIYLPIANVARIMKN AIPQTGKIAK DAKECVQECV SEFISFITSE ASERCHQEKR KTINGEDILFAMSTLGFDSY VEPLKLYLQK FREAMKGEKG IGGAVTATDG LSEELTEEAF TNQLPAGLITTDGQQQNVMV YTTSYQQISG VQQIQFS
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants. [provided by RefSeq, Jul 2008]
Uniprot Description
NFYB: Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes. Belongs to the NFYB/HAP3 subunit family.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 12q22-q23
Cellular Component: nucleoplasm; CCAAT-binding factor complex; nucleus
Molecular Function: protein binding; DNA binding; sequence-specific DNA binding; protein heterodimerization activity; protein complex binding; transcription factor activity
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; cellular lipid metabolic process
Research Articles on NFYB
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Product Notes
The NFYB nfyb (Catalog #AAA200773) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Nucleotide Sequence: ATGACAATGG ATGGTGACAG TTCTACAACA GATGCTTCTC AACTAGGAAT CTCTGCAGAC TATATTGGAG GAAGTCATTA TGTTATACAG CCTCATGATG ATACTGAGGA CAGCATGAAT GATCATGAAG ACACAAATGG TTCAAAAGAA AGTTTCAGAG AACAAGATAT ATATCTTCCA ATAGCAAACG TGGCTAGGAT AATGAAAAAT GCCATACCTC AAACGGGAAA GATTGCAAAA GATGCCAAAG AATGTGTTCA AGAATGTGTA AGTGAGTTCA TCAGTTTTAT AACATCTGAA GCAAGTGAAA GGTGCCATCA AGAGAAACGG AAAACAATCA ATGGAGAAGA TATTCTCTTT GCTATGTCTA CTTTAGGCTT TGACAGTTAT GTGGAACCTC TGAAATTATA CCTTCAGAAA TTCAGAGAGG CTATGAAAGG AGAAAAGGGA ATTGGTGGAG CAGTCACAGC TACAGATGGA CTAAGTGAAG AGCTTACAGA GGAGGCATTT ACTAACCAGT TACCAGCTGG CTTAATAACC ACAGACGGTC AACAACAAAA TGTTATGGTT TACACAACAT CATATCAACA GATTTCTGGT GTTCAGCAAA TTCAGTTTTC ATGA Translat ion Sequence: MTMDGDSSTT DASQLGISAD YIGGSHYVIQ PHDDTEDSMN DHEDTNGSKE SFREQDIYLP IANVARIMKN AIPQTGKIAK DAKECVQECV SEFISFITSE ASERCHQEKR KTINGEDILF AMSTLGFDSY VEPLKLYLQK FREAMKGEKG IGGAVTATDG LSEELTEEAF TNQLPAGLIT TDGQQQNVMV YTTSYQQISG VQQIQFS. It is sometimes possible for the material contained within the vial of "NFYB, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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