NANOS3 cdna clone
NANOS3 cDNA Clone
NCBI and Uniprot Product Information
Uniprot Description
NANOS3: Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax- dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis. Belongs to the nanos family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; Cell development/differentiation
Chromosomal Location of Human Ortholog: 19p13.13
Cellular Component: cytoplasm; nucleus; perinuclear region of cytoplasm; stress granule
Molecular Function: protein binding; RNA binding
Biological Process: germ cell development; negative regulation of translation; regulation of cell cycle; regulation of translation; spermatogenesis
Research Articles on NANOS3
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Product Notes
The NANOS3 nanos3 (Catalog #AAA1272495) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGGGACCT TTGACCTGTG GACAGATTAC CTGGGTTTGG CACACCTGGT TAGGGCTCTG AGTGGGAAAG AGGGTCCTGA AACCAGGCTG AGCCCCCAGC CAGAGCCAGA GCCAATGCTG GAGCCGGTGT CAGCCCTGGA GCCGATGCCA GCGCCGGAGT CGGTGCCAGT GCCGGGACCC AAGGATCAGA AGCGCAGCCT GGAGTCCTCG CCAGCTCCCG AACGCCTGTG CTCTTTCTGC AAACACAACG GCGAGTCCCG GGCCATCTAC CAGTCCCACG TGCTGAAGGA CGAGGCTGGC AGGGTGCTGT GTCCCATCCT GCGGGACTAC GTGTGTCCCC AGTGCGGCGC CACACGTGAG CGCGCCCACA CCCGACGCTT CTGCCCACTT ACTGGCCAGG GCTACACCTC CGTCTACAGC CACACCACCC GAAACTCGGC AGGCAAGAAG CTGGTCCGGC CTGACAAGGC GAAGACACAG GACACAGGCC ACCGCCGAGG AGGAGGAGGA GGAGCAGGTT TCAGAGGTGC CGGGAAGTCT GAGCCTTCGC CCTCCTGCTC TCCCTCCATG TCCACCTAG. It is sometimes possible for the material contained within the vial of "NANOS3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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