MUC7 cdna clone
MUC7 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a small salivary mucin, which is thought to play a role in facilitating the clearance of bacteria in the oral cavity and to aid in mastication, speech, and swallowing. The central domain of this glycoprotein contains tandem repeats, each composed of 23 amino acids. This antimicrobial protein has antibacterial and antifungal activity. The most common allele contains 6 repeats, and some alleles may be associated with susceptibility to asthma. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Oct 2014]
Uniprot Description
MUC7: May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili. Genetic variations in MUC7 are associated with susceptibility to asthma (ASTHMA). The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4q13.3
Cellular Component: Golgi lumen
Molecular Function: protein binding
Biological Process: O-glycan processing
Disease: Asthma, Susceptibility To
Research Articles on MUC7
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Product Notes
The MUC7 muc7 (Catalog #AAA1278463) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaaaactc tgccgctgtt tgtgtgcatc tgtgcactga gtgcttgctt ctcgttcagt gaaggtcgag aaagggatca tgaactacgt cacagaaggc atcatcacca atcacccaaa tctcactttg aattaccaca ttatcctgga ctgctagctc accagaagcc gttcattaga aagtcctata aatgtctgca caaacgctgt aggcctaagc ttccaccttc acctaataac ccccccaaat tcccaaatcc tcaccagcca cctaaacatc cagataaaaa tagcagtgtg gtcaacccta ccttagtggc tacaacccaa attccatctg tgactttccc atcagcttcc accaaaatta ctacccttcc aaatgtgact tttcttcccc agaatgccac caccatatct tcaagagaaa atgttaacac aagctcttct gtagctacat tagcaccagt gaattcccca gctccacaag acaccacagc tgccccaccc acaccttctg caactacacc agctccacca tcttcctcag ctccaccaga gaccacagct gccccaccca caccttctgc aactacacaa gctccaccat cttcctcagc tccaccagag accacagctg ccccacccac acctcctgca actacaccag ctccaccatc ttcctcagct ccaccagaga ccacagctgc cccacccaca ccttctgcaa ctacaccagc tccactatct tcctcagctc caccagagac cacagctgtc ccacccacac cttctgcaac taccctagac ccatcatccg cctcagctcc accagagacc acagctgccc cacccacacc ttctgcaact acaccagctc caccgtcttc cccagctcca caagagacca cagctgcccc aattaccaca cctaattctt ccccaactac tcttgcacct gacacttctg aaacttcagc tgcacccaca caccagacta ttacttcggt cactactcaa actactacta ctaaacaacc aacttcagct cctggccaaa ataaaatttc tcgatttctt ttatatatga agaatctact aaacagaatt attgacgaca tggtggagca atag. It is sometimes possible for the material contained within the vial of "MUC7, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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