MTERF cdna clone
MTERF cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a mitochondrial transcription termination factor. This protein participates in attenuating transcription from the mitochondrial genome; this attenuation allows higher levels of expression of 16S ribosomal RNA relative to the tRNA gene downstream. The product of this gene has three leucine zipper motifs bracketed by two basic domains that are all required for DNA binding. There is evidence that, for this protein, the zippers participate in intramolecular interactions that establish the three-dimensional structure required for DNA binding. [provided by RefSeq, Jul 2008]
Uniprot Description
MTERF: Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Probably requires one or more components for termination activity. Belongs to the mTERF family.
Chromosomal Location of Human Ortholog: 7q21.2
Cellular Component: mitochondrial matrix; mitochondrion
Molecular Function: double-stranded DNA binding; protein binding
Biological Process: DNA geometric change; mitochondrion organization and biogenesis; termination of mitochondrial transcription; transcription termination
Research Articles on MTERF
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Product Notes
The MTERF mterf1 (Catalog #AAA1270722) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgcagagcc tttccttagg acaaacaagc atttcaaaag gtttgaacta cctaaccatt atggcaccag gaaacctctg gcatatgaga aataactttc tctttggttc aagatgttgg atgactcgat tttcagcaga aaacatcttc aaatcagttt catttaggct ttttggtgtg aagtgtcata atacagacag tgagcctttg aaaaatgagg acctactgaa aaacttactt actatgggag tagatattga catggcaagg aaacgacagc ctggagtttt tcataggatg attaccaatg agcaggacct gaagatgttc cttctttcca aaggagctag caaagaagtg atcgctagca tcatatcaag atatccacga gcaataacac gtactcccga gaatctttca aaacggtggg atctgtggag aaagattgtg acatcagacc ttgaaattgt aaatattttg gaacgttctc ctgaatcctt ttttcggtcc aataacaacc taaacttaga gaataatata aagttcctct actcagttgg attgacccgt aaatgccttt gtcgattgtt gaccaatgcc cctcgtacct tctccaatag tcttgatctg aataaacaga tggttgaatt tttgcaggca gccggtttgt cattgggtca caatgatccc gcagattttg tcagaaagat aatttttaaa aaccctttta tcttaattca gagcaccaag cgggtgaaag ctaacattga attcttacgg tcaactttca atttgaacag tgaggaactg ctggttctga tatgtggtcc aggagctgaa atcctagacc tttccaatga ctatgccaga agaagctacg caaacatcaa agagaagctg ttttctcttg gatgtactga agaagaggta cagaagtttg tcttaagcta tccagatgtg atcttcttgg cagagaaaaa gtttaatgat aaaatagact gcctcatgga agaaaacatt agcatttcac aaataatcga aaatcctcgg gttctggatt caagcataag tactttaaaa agtcgaatca aagaattggt aaatgctggc tgtaacttga gtactttaaa catcactctt ctatcttgga gtaaaaaaag atatgaagct aaattgaaaa agttaagcag atttgcctaa. It is sometimes possible for the material contained within the vial of "MTERF, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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