MED20 cdna clone
MED20 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. A mutation in this gene has been associated with a novel infantile-onset neurodegenerative movement disorder. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Mar 2015]
Uniprot Description
TRFP: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Belongs to the Mediator complex subunit 20 family.
Chromosomal Location of Human Ortholog: 6p21.1
Cellular Component: nucleoplasm; Srb-mediator complex
Molecular Function: protein binding; transcription coactivator activity
Biological Process: transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter
Research Articles on MED20
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Product Notes
The MED20 med20 (Catalog #AAA1271827) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgggagtga cttgtgtgtc ccagatgcct gtggccgagg gcaagagtgt tcagcaaacc gtagagctcc ttacccggaa attggagatg cttggggcag agaagcaagg aacattttgt gtggactgtg agacttacca tacggccgcc tctacccttg gcagccaagg tcagaccggg aagctgatgt atgtgatgca caactcagag tacccattga gctgtttcgc cctctttgag aatggccctt gccttattgc tgacaccaac tttgatgtgc ttatggtgaa gctcaagggc tttttccaga gtgctaaggc cagcaagatt gagacccggg gcaccaggta ccagtactgt gacttcctgg tgaaggtggg cacggtcaca atggggccca gtgcccgggg catctctgtg gaggtggagt atggcccctg tgtggtagct agtgactgct ggagtctgct gctcgagttc ctacagagtt ttctaggcag ccacacacca ggggctcccg cagtgtttgg gaacagacat gatgcggtct acggcccagc agataccatg gtccagtaca tggaactctt caacaagatc cgcaagcagc agcaggtgcc ggtggctggg attcgttag. It is sometimes possible for the material contained within the vial of "MED20, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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