LZTFL1 cdna clone
LZTFL1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a ubiquitously expressed protein that localizes to the cytoplasm. This protein interacts with Bardet-Biedl Syndrome (BBS) proteins and, through its interaction with BBS protein complexes, regulates protein trafficking to the ciliary membrane. Nonsense mutations in this gene cause a form of Bardet-Biedl Syndrome; a ciliopathy characterized in part by polydactyly, obesity, cognitive impairment, hypogonadism, and kidney failure. This gene may also function as a tumor suppressor; possibly by interacting with E-cadherin and the actin cytoskeleton and thereby regulating the transition of epithelial cells to mesenchymal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2013]
Uniprot Description
LZTFL1: Belongs to the LZTFL1 family.
Chromosomal Location of Human Ortholog: 3p21.3
Cellular Component: cytosol
Molecular Function: identical protein binding; protein binding; protein complex binding
Disease: Bardet-biedl Syndrome 17
Research Articles on LZTFL1
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Product Notes
The LZTFL1 lztfl1 (Catalog #AAA1269472) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcagagt tgggcctaaa tgagcaccat caaaatgaag ttattaatta tatgcgtttt gctcgttcaa agagaggctt gagactcaaa actgtagatt cctgcttcca agacctcaag gagagcaggc tggtggagga caccttcacc atagatgaag tctctgaagt cctcaatgga ttacaagctg tggttcatag tgaggtggaa tctgagctca tcaacactgc ctataccaat gtgttacttc tgcgacagct gtttgcacaa gctgagaagt ggtatcttaa gctacagaca gacatctctg aacttgaaaa ccgagaatta ttagaacaag ttgcagaatt tgaaaaagca gagattacat cttcaaacaa aaagcccatc ttagatgtca caaagccaaa acttgctcca cttaatgaag gtggaacagc agaactccta aacaaggaaa ttttaagact tcaagaagag aatgagaaat tgaagtcaag gttgaagacc attgaaatac aggctacaaa tgcactggat gaaaagtcaa aactagaaaa agcactgcaa gatttacagc ttgatcaagg aaatcaaaag gattttataa aggcccaaga cttaagtaac ttagaaaaca ctgtcgctgc cttaaagagt gagtttcaga agacacttaa tgacaagaca gaaaaccaga agtcactgga ggagaatctg gcgacagcca agcacgatct actcagggtt caggagcagc tgcacatggc tgaaaaggaa ttagaaaaga aatttcagca aacagcagct tatcgaaaca tgaaagagat tcttaccaag aagaatgacc aaatcaaaga tctgaggaaa agactggcac aatatgaacc tgaagattaa. It is sometimes possible for the material contained within the vial of "LZTFL1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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