ITK cdna clone
ITK cDNA Clone
Gene Names
ITK; EMT; LYK; LPFS1; PSCTK2
Synonyms
ITK; ITK cDNA Clone; ITK cdna clone
Sequence
ATGAACAACTTTATCCTCCTGGAAGAACAGCTCATCAAGAAATCCCAACAAAAGAGAAGAACTTCTCCCTCGAACTTTAAAGTCCGCTTCTTTGTGTTAACCAAAGCCAGCCTGGCATACTTTGAAGATCGTCATGGGAAGAAGCGCACGCTGAAGGGGTCCATTGAGCTCTCCCGAATCAAATGTGTTGAGATTGTGAAAAGTGACATCAGCATCCCATGCCACTATAAATACCCGTTTCAGGTGGTGCATGACAACTACCTCCTATATGTGTTTGCTCCAGATCGTGAGAGCCGGCAGCGCTGGGTGCTGGCCCTTAAAGAAGAAACGAGGAATAATAACAGTTTGGTGCCTAAATATCATCCTAATTTCTGGATGGATGGGAAGTGGAGGTGCTGTTCTCAGCTGGAGAAGCTTGCAACAGGCTGTGCCCAATATGATCCAACCAAGAATGCTTCAAAGAAGCCTCTTCCTCCTACTCCTGAAGACAACAGGCGACCACTTTGGGAACCTGAAGAAACTGTGGTCATTGCCTTATATGACTACCAAACCAATGATCCTCAGGAACTCGCACTGCGGCGCAACGAAGAGTACTGCCTGCTGGACAGTTCTGAGATTCACTGGTGGAGAGTCCAGGACAGGAATGGGCATGAAGGATATGTACCAAGCAGTTATCTGGTGGAAAAATCTCCAAATAATCTGGAAACCTATGAGTGGTACAATAAGAGTATCAGCCGAGACAAAGCTGAAAAACTTCTTTTGGACACAGGCAAAGAAGGAGCCTTCATGGTAAGGGATTCCAGGACTGCAGGAACATACACCGTGTCTGTTTTCACCAAGGCTGTTGTAAGTGAGAACAATCCCTGTATAAAGCATTATCACATCAAGGAAACAAATGACAATCCTAAGCGATACTATGTGGCTGAAAAGTATGTGTTCGATTCCATCCCTCTTCTCATCAACTATCACCAACATAATGGAGGAGGCCTGGTGACTCGACTCCGGTATCCAGTTTGTTTTGGGAGGCAGAAAGCCCCAGTTACAGCAGGGCTGAGATACGGGAAATGGGTGATCGACCCCTCAGAGCTCACTTTTGTGCAAGAGATTGGCAGTGGGCAATTTGGGTTGGTGCATCTGGGCTACTGGCTCAACAAGGACAAGGTGGCTATCAAAACCATTCGGGAAGGGGCTATGTCAGAAGAGGACTTCATAGAGGAGGCTGAAGTAATGATGAAACTCTCTCATCCCAAACTGGTGCAGCTGTATGGGGTGTGCCTGGAGCAGGCCCCCATCTGCCTGGTGTTTGAGTTCATGGAGCACGGCTGCCTGTCAGATTATCTACGCACCCAGCGGGGACTTTTTGCTGCAGAGACCCTGCTGGGCATGTGTCTGGATGTGTGTGAGGGCATGGCCTACCTGGAAGAGGCATGTGTCATCCACAGAGACTTGGCTGCCAGAAATTGTTTGGTGGGAGAAAACCAAGTCATCAAGGTGTCTGACTTTGGGATGACAAGGTTCGTTCTGGATGATCAGTACACCAGTTCCACAGGCACCAAATTCCCGGTGAAGTGGGCATCCCCAGAGGTTTTCTCTTTCAGTCGCTATAGCAGCAAGTCCGATGTGTGGTCATTTGGTGTGCTGATGTGGGAAGTTTTCAGTGAAGGCAAAATCCCGTATGAAAACCGAAGCAACTCAGAGGTGGTGGAAGACATCAGTACCGGATTTCGGTTGTACAAGCCCCGGCTGGCCTCCACACACGTCTACCAGATTATGAATCACTGCTGGAAAGAGAGACCAGAAGATCGGCCAGCCTTCTCCAGACTGCTGCGTCAACTGGCTGAAATTGCAGAATCAGGACTTTAG
Sequence Length
1863
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
71,831 Da
NCBI Official Full Name
Homo sapiens IL2-inducible T-cell kinase, mRNA
NCBI Official Synonym Full Names
IL2 inducible T-cell kinase
NCBI Official Symbol
ITK
NCBI Official Synonym Symbols
EMT; LYK; LPFS1; PSCTK2
NCBI Protein Information
tyrosine-protein kinase ITK/TSK
UniProt Protein Name
Tyrosine-protein kinase ITK/TSK
Protein Family
UniProt Gene Name
ITK
UniProt Synonym Gene Names
EMT; LYK; IL-2-inducible T-cell kinase
UniProt Entry Name
ITK_HUMAN
NCBI Description
This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
Uniprot Description
ITK: an intracellular tyrosine kinase of the Tec family expressed in T-cells. The protein contains both SH2 and SH3 domains and plays a role in T-cell proliferation and differentiation. Itk-deficient murine T cells display defects in TCR/CD3-induced actin polymerization.
Protein type: EC 2.7.10.2; Kinase, protein; Protein kinase, TK; Protein kinase, tyrosine (non-receptor); TK group; Tec family
Chromosomal Location of Human Ortholog: 5q31-q32
Cellular Component: cytosol; extrinsic to internal side of plasma membrane
Molecular Function: non-membrane spanning protein tyrosine kinase activity; protein binding; receptor binding
Biological Process: adaptive immune response; cellular defense response; cytokine production; innate immune response; NK T cell differentiation; phospholipase C activation; regulation of cell proliferation; signal transduction; T cell activation; T cell receptor signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway
Disease: Lymphoproliferative Syndrome 1
Research Articles on ITK
Similar Products
Product Notes
The ITK itk (Catalog #AAA1278707) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGAACAACT TTATCCTCCT GGAAGAACAG CTCATCAAGA AATCCCAACA AAAGAGAAGA ACTTCTCCCT CGAACTTTAA AGTCCGCTTC TTTGTGTTAA CCAAAGCCAG CCTGGCATAC TTTGAAGATC GTCATGGGAA GAAGCGCACG CTGAAGGGGT CCATTGAGCT CTCCCGAATC AAATGTGTTG AGATTGTGAA AAGTGACATC AGCATCCCAT GCCACTATAA ATACCCGTTT CAGGTGGTGC ATGACAACTA CCTCCTATAT GTGTTTGCTC CAGATCGTGA GAGCCGGCAG CGCTGGGTGC TGGCCCTTAA AGAAGAAACG AGGAATAATA ACAGTTTGGT GCCTAAATAT CATCCTAATT TCTGGATGGA TGGGAAGTGG AGGTGCTGTT CTCAGCTGGA GAAGCTTGCA ACAGGCTGTG CCCAATATGA TCCAACCAAG AATGCTTCAA AGAAGCCTCT TCCTCCTACT CCTGAAGACA ACAGGCGACC ACTTTGGGAA CCTGAAGAAA CTGTGGTCAT TGCCTTATAT GACTACCAAA CCAATGATCC TCAGGAACTC GCACTGCGGC GCAACGAAGA GTACTGCCTG CTGGACAGTT CTGAGATTCA CTGGTGGAGA GTCCAGGACA GGAATGGGCA TGAAGGATAT GTACCAAGCA GTTATCTGGT GGAAAAATCT CCAAATAATC TGGAAACCTA TGAGTGGTAC AATAAGAGTA TCAGCCGAGA CAAAGCTGAA AAACTTCTTT TGGACACAGG CAAAGAAGGA GCCTTCATGG TAAGGGATTC CAGGACTGCA GGAACATACA CCGTGTCTGT TTTCACCAAG GCTGTTGTAA GTGAGAACAA TCCCTGTATA AAGCATTATC ACATCAAGGA AACAAATGAC AATCCTAAGC GATACTATGT GGCTGAAAAG TATGTGTTCG ATTCCATCCC TCTTCTCATC AACTATCACC AACATAATGG AGGAGGCCTG GTGACTCGAC TCCGGTATCC AGTTTGTTTT GGGAGGCAGA AAGCCCCAGT TACAGCAGGG CTGAGATACG GGAAATGGGT GATCGACCCC TCAGAGCTCA CTTTTGTGCA AGAGATTGGC AGTGGGCAAT TTGGGTTGGT GCATCTGGGC TACTGGCTCA ACAAGGACAA GGTGGCTATC AAAACCATTC GGGAAGGGGC TATGTCAGAA GAGGACTTCA TAGAGGAGGC TGAAGTAATG ATGAAACTCT CTCATCCCAA ACTGGTGCAG CTGTATGGGG TGTGCCTGGA GCAGGCCCCC ATCTGCCTGG TGTTTGAGTT CATGGAGCAC GGCTGCCTGT CAGATTATCT ACGCACCCAG CGGGGACTTT TTGCTGCAGA GACCCTGCTG GGCATGTGTC TGGATGTGTG TGAGGGCATG GCCTACCTGG AAGAGGCATG TGTCATCCAC AGAGACTTGG CTGCCAGAAA TTGTTTGGTG GGAGAAAACC AAGTCATCAA GGTGTCTGAC TTTGGGATGA CAAGGTTCGT TCTGGATGAT CAGTACACCA GTTCCACAGG CACCAAATTC CCGGTGAAGT GGGCATCCCC AGAGGTTTTC TCTTTCAGTC GCTATAGCAG CAAGTCCGAT GTGTGGTCAT TTGGTGTGCT GATGTGGGAA GTTTTCAGTG AAGGCAAAAT CCCGTATGAA AACCGAAGCA ACTCAGAGGT GGTGGAAGAC ATCAGTACCG GATTTCGGTT GTACAAGCCC CGGCTGGCCT CCACACACGT CTACCAGATT ATGAATCACT GCTGGAAAGA GAGACCAGAA GATCGGCCAG CCTTCTCCAG ACTGCTGCGT CAACTGGCTG AAATTGCAGA ATCAGGACTT TAG. It is sometimes possible for the material contained within the vial of "ITK, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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