IL4I1 cdna clone
IL4I1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Uniprot Description
IL4I1: Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation. Belongs to the flavin monoamine oxidase family. FIG1 subfamily. 2 isoforms of the human protein are produced by alternative promoter.
Protein type: EC 1.4.3.2; Secreted; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - cysteine and methionine; Amino Acid Metabolism - phenylalanine; Oxidoreductase; Amino Acid Metabolism - phenylalanine, tyrosine and tryptophan biosynthesis; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Secreted, signal peptide; Amino Acid Metabolism - alanine, aspartate and glutamate; Amino Acid Metabolism - tryptophan
Chromosomal Location of Human Ortholog: 19q13.3-q13.4
Cellular Component: lysosome; extracellular region
Molecular Function: L-amino-acid oxidase activity
Research Articles on IL4I1
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Product Notes
The IL4I1 il4i1 (Catalog #AAA1275408) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGCCCAACG ATGACTTCTG TCCTGGGCTA ACCATAAAGG CCATGGGTGC TGAGAGAGCC CCCCAGAGGC AGCCATGCAC CCTGCACCTC CTCGTCCTCG TCCCCATCCT CCTCAGCCTG GTGGCCTCCC AGGACTGGAA GGCTGAACGC AGCCAAGACC CCTTCGAGAA ATGCATGCAG GATCCTGACT ATGAGCAGCT GCTCAAGGTG GTGACCTGGG GGCTCAATCG GACCCTGAAG CCCCAGAGGG TGATTGTGGT TGGCGCTGGT GTGGCCGGGC TGGTGGCCGC CAAGGTGCTC AGCGATGCTG GACACAAGGT CACCATCCTG GAGGCAGATA ACAGGATCGG GGGCCGCATC TTCACCTACC GGGACCAGAA CATGGGCTGG ATTGGGGAGC TGGGAGCCAT GCGCATGCCC AGCTCTCACA GGATCCTCCA CAAGCTCTGC CAGGGCCTGG GGCTCAACCT GACCAAGTTC ACCCAGTACG ACAAGAACAC GTGGACGGAG GTGCACGAAG TGAAGCTGCG CAACTATGTG GTGGAGAAGG TGCCCGAGAA GCTGGGCTAC GCCTTGCGTC CCCAGGAAAA GGGCCACTCG CCCGAAGACA TCTACCAGAT GGCTCTCAAC CAGGCCCTCA AAGACCTCAA GGCACTGGGC TGCAGAAAGG CGATGAAGAA GTTTGAAAGG CACACGCTCT TGGAATATCT TCTCGGGGAG GGGAACCTGA GCCGGCCGGC CGTGCAGCTT CTGGGAGACG TGATGTCCGA GGATGGCTTC TTCTATCTCA GCTTCGCCGA GGCCCTCCGG GCCCACAGCT GCCTCAGCGA CAGACTCCAG TACAGCCGCA TCGTGGGTGG CTGGGACCTG CTGCCGCGCG CGCTGCTGAG CTCGCTGTCC GGGCTTGTGC TGTTGAACGC GCCCGTGGTG GCGATGACCC AGGGACCGCA CGATGTGCAC GTGCAGATCG AGACCTCTCC CCCGGCGCGG AATCTGAAGG TGCTGAAGGC CGACGTGGTG CTGCTGACGG CGAGCGGACC GGCGGTGAAG CGCATCACCT TCTCGCCGCC GCTGCCCCGC CACATGCAGG AGGCGCTGCG GAGGCTGCAC TACGTGCCGG CCACCAAGGT GTTCCTAAGC TTCCGCAGGC CCTTCTGGCG CGAGGAGCAC ATTGAAGGCG GCCACTCAAA CACCGATCGC CCGTCGCGCA TGATTTTCTA CCCGCCGCCG CGCGAGGGCG CGCTGCTGCT GGCCTCGTAC ACGTGGTCGG ACGCGGCGGC AGCGTTCGCC GGCTTGAGCC GGGAAGAGGC GTTGCGCTTG GCGCTCGACG ACGTGGCGGC ATTGCACGGG CCTGTCGTGC GCCAGCTCTG GGACGGCACC GGCGTCGTCA AGCGTTGGGC GGAGGACCAG CACAGCCAGG GTGGCTTTGT GGTACAGCCG CCGGCGCTCT GGCAAACCGA AAAGGATGAC TGGACGGTCC CTTATGGCCG CATCTACTTT GCCGGCGAGC ACACCGCCTA CCCGCACGGC TGGGTGGAGA CGGCGGTCAA GTCGGCGCTG CGCGCCGCCA TCAAGATCAA CAGCCGGAAG GGGCCTGCAT CGGACACGGC CAGCCCCGAG GGGCACGCAT CTGACATGGA GGGGCAGGGG CATGTGCATG GGGTGGCCAG CAGCCCCTCG CATGACCTGG CAAAGGAAGA AGGCAGCCAC CCTCCAGTCC AAGGCCAGTT ATCTCTCCAA AACACGACCC ACACGAGGAC CTCGCATTAA. It is sometimes possible for the material contained within the vial of "IL4I1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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