Vector Map
HSP90AA1 cdna clone
HSP90AA1 cDNA Clone
Vector Map
Vector Map
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Uniprot Description
HSP90A: a molecular chaperone of the heat shock protein 90 family. Has ATPase activity. Known to interact with a wide variety of proteins including steroid hormone receptors, neuropeptide Y, FKBP51/54, and FKBP52. G protein-coupled receptor kinases are stabilized by interacting with HSP 90. Hsp70 and Hsp90 promote tau solubility and tau binding to microtubules, reducing insoluble tau phosphorylation of tau.
Protein type: Chaperone; Heat shock protein
Chromosomal Location of Human Ortholog: 14q32.33
Cellular Component: nucleoplasm; membrane; mitochondrion; cytoplasm; extracellular region; plasma membrane; melanosome; nucleus; cytosol
Molecular Function: identical protein binding; protein binding; protein homodimerization activity; TPR domain binding; nitric-oxide synthase regulator activity; unfolded protein binding; ATPase activity; nucleotide binding; ATP binding
Biological Process: axon guidance; receptor-mediated endocytosis; positive regulation of nitric oxide biosynthetic process; organelle organization and biogenesis; signal transduction; protein import into mitochondrial outer membrane; nitric oxide metabolic process; response to unfolded protein; mitochondrial transport; innate immune response; protein refolding; mitotic cell cycle; regulation of nitric-oxide synthase activity; vascular endothelial growth factor receptor signaling pathway; chaperone-mediated protein complex assembly; G2/M transition of mitotic cell cycle
Research Articles on HSP90AA1
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Product Notes
The HSP90AA1 hsp90aa1 (Catalog #AAA1271514) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGCCTGAGG AAACCCAGAC CCAAGACCAA CCGATGGAGG AGGAGGAGGT TGAGACGTTC GCCTTTCAGG CAGAAATTGC CCAGTTGATG TCATTGATCA TCAATACTTT CTACTCGAAC AAAGAGATCT TTCTGAGAGA GCTCATTTCA AATTCATCAG ATGCATTGGA CAAAATCCGG TATGAAAGCT TGACAGATCC CAGTAAATTA GACTCTGGGA AAGAGCTGCA TATTAACCTT ATACCGAACA AACAAGATCG AACTCTCACT ATTGTGGATA CTGGAATTGG AATGACCAAG GCTGACTTGA TCAATAACCT TGGTACTATC GCCAAGTCTG GGACCAAAGC GTTCATGGAA GCTTTGCAGG CTGGTGCAGA TATCTCTATG ATTGGCCAGT TCGGTGTTGG TTTTTATTCT GCTTATTTGG TTGCTGAGAA AGTAACTGTG ATCACCAAAC ATAACGATGA TGAGCAGTAC GCTTGGGAGT CCTCAGCAGG GGGATCATTC ACAGTGAGGA CAGACACAGG TGAACCTATG GGTCGTGGAA CAAAAGTTAT CCTACACCTG AAAGAAGACC AAACTGAGTA CTTGGAGGAA CGAAGAATAA AGGAGATTGT GAAGAAACAT TCTCAGTTTA TTGGATATCC CATTACTCTT TTTGTGGAGA AGGAACGTGA TAAAGAAGTA AGCGATGATG AGGCTGAAGA AAAGGAAGAC AAAGAAGAAG AAAAAGAAAA AGAAGAGAAA GAGTCGGAAG ACAAACCTGA AATTGAAGAT GTTGGTTCTG ATGAGGAAGA AGAAAAGAAG GATGGTGACA AGAAGAAGAA GAAGAAGATT AAGGAAAAGT ACATCGATCA AGAAGAGCTC AACAAAACAA AGCCCATCTG GACCAGAAAT CCCGACGATA TTACTAATGA GGAGTACGGA GAATTCTATA AGAGCTTGAC CAATGACTGG GAAGATCACT TGGCAGTGAA GCATTTTTCA GTTGAAGGAC AGTTGGAATT CAGAGCCCTT CTATTTGTCC CACGACGTGC TCCTTTTGAT CTGTTTGAAA ACAGAAAGAA AAAGAACAAT ATCAAATTGT ATGTACGCAG AGTTTTCATC ATGGATAACT GTGAGGAGCT AATCCCTGAA TATCTGAACT TCATTAGAGG GGTGGTAGAC TCGGAGGATC TCCCTCTAAA CATATCCCGT GAGATGTTGC AACAAAGCAA AATTTTGAAA GTTATCAGGA AGAATTTGGT CAAAAAATGC TTAGAACTCT TTACTGAACT GGCGGAAGAT AAAGAGAACT ACAAGAAATT CTATGAGCAG TTCTCTAAAA ACATAAAGCT TGGAATACAC GAAGACTCTC AAAATCGGAA GAAGCTTTCA GAGCTGTTAA GGTACTACAC ATCTGCCTCT GGTGATGAGA TGGTTTCTCT CAAGGACTAC TGCACCAGAA TGAAGGAGAA CCAGAAACAT ATCTATTATA TCACAGGTGA GACCAAGGAC CAGGTAGCTA ACTCAGCCTT TGTGGAACGT CTTCGGAAAC ATGGCTTAGA AGTGATCTAT ATGATTGAGC CCATTGATGA GTACTGTGTC CAACAGCTGA AGGAATTTGA GGGGAAGACT TTAGTGTCAG TCACCAAAGA AGGCCTGGAA CTTCCAGAGG ATGAAGAAGA GAAAAAGAAG CAGGAAGAGA AAAAAACAAA GTTTGAGAAC CTCTGCAAAA TCATGAAAGA CATATTGGAG AAAAAAGTTG AAAAGGTGGT TGTGTCAAAC CGATTGGTGA CATCTCCATG CTGTATTGTC ACAAGCACAT ATGGCTGGAC AGCAAACATG GAGAGAATCA TGAAAGCTCA AGCCCTAAGA GACAACTCAA CAATGGGTTA CATGGCAGCA AAGAAACACC TGGAGATAAA CCCTGACCAT TCCATTATTG AGACCTTAAG GCAAAAGGCA GAGGCTGATA AGAACGACAA GTCTGTGAAG GATCTGGTCA TCTTGCTTTA TGAAACTGCG CTCCTGTCTT CTGGCTTCAG TCTGGAAGAT CCCCAGACAC ATGCTAACAG GATCTACAGG ATGATCAAAC TTGGTCTGGG TATTGATGAA GATGACCCTA CTGCTGATGA TACCAGTGCT GCTGTAACTG AAGAAATGCC ACCCCTTGAA GGAGATGACG ACACATCACG CATGGAAGAA GTAGACTAA. It is sometimes possible for the material contained within the vial of "HSP90AA1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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