HMMR cdna clone
HMMR cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Dec 2008]
Uniprot Description
HMMR: Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular- regulated kinase (ERK) activity. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, misc.
Chromosomal Location of Human Ortholog: 5q34
Cellular Component: cytosol; membrane; plasma membrane
Molecular Function: hyaluronic acid binding; protein binding
Biological Process: G2/M transition of mitotic cell cycle; hyaluronan catabolic process
Disease: Breast Cancer
Research Articles on HMMR
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Product Notes
The HMMR hmmr (Catalog #AAA1266506) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGTCCTTTC CTAAGGCGCC CTTGAAACGA TTCAATGACC CTTCTGGTTG TGCACCATCT CCAGGTGCTT ATGATGTTAA AACTTTAGAA GTATTGAAAG GACCAGTATC CTTTCAGAAA TCACAAAGAT TTAAACAACA AAAAGAATCT AAACAAAATC TTAATGTTGA CAAAGATACT ACCTTGCCTG CTTCAGCTAG AAAAGTTAAG TCTTCGGAAT CAAAGAAGGA ATCTCAAAAG AATGATAAAG ATTTGAAGAT ATTAGAGAAA GAGATTTGTG TTCTTCTACA GGAACGTGGT GCCCAGGACA GGCGGATCCA GGATCTGGAA ACTGAGTTGG AAAAGATGGA AGCAAGGCTA AATGCTGCAC TAAGGGAAAA AACATCTCTC TCTGCAAATA ATGCTACACT GGAAAAACAA CTTATTGAAT TGACCAGGAC TAATGAACTA CTAAAATCTA AGTTTTCTGA AAATGGTAAC CAGAAGAATT TGAGAATTCT AAGCTTGGAG TTGATGAAAC TTAGAAACAA AAGAGAAACA AAGATGAGGG GTATGATGGC TAAGCAAGAA GGCATGGAGA TGAAGCTGCA GGTCACCCAA AGGAGTCTCG AAGAGTCTCA AGGGAAAATA GCCCAACTGG AGGGAAAACT TGTTTCAATA GAGAAAGAAA AGATTGATGA AAAATCTGAA ACAGAAAAAC TCTTGGAATA CATCGAAGAA ATTAGTTGTG CTTCAGATCA AGTGGAAAAA TACAAGCTAG ATATTGCCCA GTTAGAAGAA AATTTGAAAG AGAAGAATGA TGAAATTTTA AGCCTTAAGC AGTCTCTTGA GGAGAATATT GTTATATTAT CTAAACAAGT AGAAGATCTA AATGTGAAAT GTCAGCTGCT TGAAAAAGAA AAAGAAGACC ATGTCAACAG GAATAGAGAA CACAACGAAA ATCTAAATGC AGAGATGCAA AACTTAAAAC AGAAGTTTAT TCTTGAACAA CAGGAACGTG AAAAGCTTCA ACAAAAAGAA TTACAAATTG ATTCACTTCT GCAACAAGAG AAAGAATTAT CTTCGAGTCT TCATCAGAAG CTCTGTTCTT TTCAAGAGGA AATGGCTAAA GAGAAGAATC TGTTTGAGGA AGAATTAAAG CAAACACTGG ATGAGCTTGA TAAATTACAG CAAAAGGAGG AACAAGCTGA AAGGCTGGTC AAGCAATTGG AAGAGGAAGC AAAATCTAGA GCTGAAGAAT TAAAACTCCT AGAAGAAAAG CTGAAAGGGA AGGAGGCTGA ACTGGAGAAA AGTAGTGCTG CTCATACCCA GGCCACCCTG CTTTTGCAGG AAAAGTATGA CAGTATGGTG CAAAGCCTTG AAGATGTTAC TGCTCAATTT GAAAGCTATA AAGCGTTAAC AGCCAGTGAG ATAGAAGATC TTAAGCTGGA GAACTCATCA TTACAGGAAA AAGTGGCCAA GGCTGGGAAA AATGCAGAGG ATGTTCAGCA TCAGATTTTG GCAACTGAGA GCTCAAATCA AGAATATGTA AGGATGCTTC TAGATCTGCA GACCAAGTCA GCACTAAAGG AAACAGAAAT TAAAGAAATC ACAGTTTCTT TTCTTCAAAA AATAACTGAT TTGCAGAACC AACTCAAGCA ACAGGAGGAA GACTTTAGAA AACAGCTGGA AGATGAAGAA GGAAGAAAAG CTGAAAAAGA AAATACAACA GCAGAATTAA CTGAAGAAAT TAACAAGTGG CGTCTCCTCT ATGAAGAACT ATATAATAAA ACAAAACCTT TTCAGCTACA ACTAGATGCT TTTGAAGTAG AAAAACAGGC ATTGTTGAAT GAACATGGTG CAGCTCAGGA ACAGCTAAAT AAAATAAGAG ATTCATATGC TAAATTATTG GGTCATCAGA ATTTGAAACA AAAAATCAAG CATGTTGTGA AGTTGAAAGA TGAAAATAGC CAACTCAAAT CGGAAGTATC AAAACTCCGC TGTCAGCTTG CTAAAAAAAA ACAAAGTGAG ACAAAACTTC AAGAGGAATT GAATAAAGTT CTAGGTATCA AACACTTTGA TCCTTCAAAG GCTTTTCATC ATGAAAGTAA AGAAAATTTT GCCCTGAAGA CCCCATTAAA AGAAGGCAAT ACAAACTGTT ACCGAGCTCC TATGGAGTGT CAAGAATCAT GGAAGTAA. It is sometimes possible for the material contained within the vial of "HMMR, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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