HEBP1 cdna clone

HEBP1

Cat. Num. AAA200857

• Gene Names: HEBP1; HBP; HEBP
• Synonyms: HEBP1; HBP; HEBP; HEBP1 cdna clone

• Form/Format: Lyophilized
• Sequence: Nucleotide Sequence: ATGTTGGGCATGATCAAGAACTCGCTGTTCGGAAGCGTAGAGACGTGGCCTTGGCAGGTCCTAAGCAAAGGGGACAAGGAAGAAGTTGCCTATGAAGAAAGGGCCTGTGAAGGCGGCAAATTTGCCACAGTAGAAGTGACAGATAAGCCTGTGGATGAGGCTCTACGGGAAGCAATGCCCAAGGTCGCAAAGTATGCGGGGGGCACCAATGACAAGGGAATTGGGATGGGGATGACAGTCCCTATTTCCTTTGCTGTGTTCCCCAATGAAGATGGCTCTCTGCAGAAGAAATTAAAAGTCTGGTTCCGGATTCCAAACCAATTTCAAAGCGACCCACCAGCTCCCAGTGACAAAAGCGTTAAGATTGAGGAACGGGAAGGCATCACTGTCTATTCCATGCAGTTTGGTGGTTATGCCAAGGAAGCAGACTACGTAGCACAAGCCACCCGTCTGCGTGCTGCCCTGGAGGGCACAGCCACCTACCGGGGGGACATCTACTTCTGCACGGGTTATGACCCTCCCATGAAGCCCTACGGACGGCGCAATGAGATCTGGCTGTTGAAGACATGA; ; Translation Sequence: MLGMIKNSLF GSVETWPWQV LSKGDKEEVA YEERACEGGK FATVEVTDKP VDEALREAMP KVAKYAGGTN DKGIGMGMTV PISFAVFPNE DGSLQKKLKV WFRIPNQFQS DPPAPSDKSV KIEEREGITV YSMQFGGYAK EADYVAQATR LRAALEGTAT YRGDIYFCTG YDPPMKPYGR RNEIWLLKT
• Sequence Length: 189

• Species: Human
• Chromosome Location: 12p13.1
• OMIM Reference Number: 605826
• cDNA Size: 570bp
• Vector Description: This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
• Vector: (puc19-derived cloning vector)
• Preparation Before Usage: 1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.
• Preparation and Storage: Store the plasmid at -20 degree C.

Related Product Information for HEBP1 cdna clone

HEBP1 is an intracellular tetrapyrrole-binding protein. It includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells.

Product Categories/Family for HEBP1 cdna clone

Metabolism

NCBI and Uniprot Product Information

• NCBI GI #: 20336761
• NCBI GeneID: 50865
• NCBI Accession #: NP_057071.2
• NCBI GenBank Nucleotide #: NM_015987.4
• UniProt Accession #: Q9NRV9
• NCBI Official Full Name: heme-binding protein 1
• NCBI Official Synonym Full Names: heme binding protein 1
• NCBI Official Symbol: HEBP1
• NCBI Official Synonym Symbols: HBP; HEBP
• NCBI Protein Information: heme-binding protein 1
• UniProt Protein Name: Heme-binding protein 1
• Protein Family: Heme-binding protein
• UniProt Gene Name: HEBP1
• UniProt Synonym Gene Names: HBP
• UniProt Entry Name: HEBP1_HUMAN

NCBI Description

The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells. [provided by RefSeq, Jul 2008]

Uniprot Description

HEBP1: May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N- methylprotoporphyrin with similar affinities. Belongs to the HEBP family.

Chromosomal Location of Human Ortholog: 12p13.1

Cellular Component: mitochondrion; extracellular region; cytosol

Molecular Function: heme binding

Biological Process: circadian rhythm