GRHL3 cdna clone
GRHL3 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the grainyhead family of transcription factors. The encoded protein may function as a transcription factor during development, and has been shown to stimulate migration of endothelial cells. Multiple transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Aug 2010]
Uniprot Description
GRHL3: May function as a transcription factor. Belongs to the grh/CP2 family. Grainyhead subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 1p36.11
Cellular Component: cytoplasm; nucleoplasm; nucleus
Molecular Function: chromatin DNA binding; protein binding; sequence-specific DNA binding
Biological Process: epidermis development; neural tube closure; positive regulation of transcription from RNA polymerase II promoter; regulation of actin cytoskeleton organization and biogenesis
Disease: Van Der Woude Syndrome 2
Research Articles on GRHL3
Similar Products
Product Notes
The GRHL3 grhl3 (Catalog #AAA1276958) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgagagtca atggagatga tgacagtgtt gcggccttga gcttcctcta tgattactac atgggtccca aggagaagcg gatattgtcc tccagcactg ggggcaggaa tgaccaagga aagaggtact accatggcat ggaatatgag acggacctca ctccccttga aagccccaca cacctcatga aattcctgac agagaacgtg tctggaaccc cagagtaccc agatttgctc aagaagaata acctgatgag cttggagggg gccttgccca cccctggcaa ggcagctccc ctccctgcag gccccagcaa gctggaggcc ggctctgtgg acagctacct gttacccacc actgatatgt atgataatgg ctccctcaac tccttgtttg agagcattca tggggtgccg cccacacagc gctggcagcc agacagcacc ttcaaagatg acccacagga gtcgatgctc ttcccagata tcctgaaaac ctccccggaa cccccatgtc cagaggacta ccccagcctc aaaagtgact ttgaatacac cctgggctcc cccaaagcca tccacatcaa gtcaggcgag tcacccatgg cctacctcaa caaaggccag ttctaccccg tcaccctgcg gaccccagca ggtggcaaag gccttgcctt gtcctccaac aaagtcaaga gtgtggtgat ggttgtcttc gacaatgaga aggtcccagt agagcagctg cgcttctgga agcactggca ttcccggcaa cccactgcca agcagcgggt cattgacgtg gctgactgca aagaaaactt caacactgtg gagcacattg aggaggtggc ctataatgca ctgtcctttg tgtggaacgt gaatgaagag gccaaggtgt tcatcggcgt aaactgtctg agcacagact tttcctcaca aaagggggtg aagggtgtcc ccctgaacct gcagattgac acctatgact gtggcttggg cactgagcgc ctggtacacc gtgctgtctg ccagatcaag atcttctgtg acaagggagc tgagaggaag atgcgcgatg acgagcggaa gcagttccgg aggaaggtca agtgccctga ctccagcaac agtggcgtca agggctgcct gctgtcgggc ttcaggggca atgagacgac ctaccttcgg ccagagactg acctggagac gccacccgtg ctgttcatcc ccaatgtgca cttctccagc ctgcagcgct ctggaggggc agccccctcg gcaggaccca gcagctccaa caggctgcct ctgaagcgta cctgctcgcc cttcactgag gagtttgagc ctctgccctc caagcaggcc aaggaaggcg accttcagag agttctgctg tatgtgcgga gggagactga ggaggtgttt gacgcgctca tgttgaagac cccagacctg aaggggctga ggaatgcgat ctctgagaag tatgggttcc ctgaagagaa catttacaaa gtctacaaga aatgcaagcg aggaatctta gtcaacatgg acaacaacat cattcagcat tacagcaacc acgtcgcctt cctgctggac atgggggagc tggacggcaa aattcagatc atccttaagg agctgtaa. It is sometimes possible for the material contained within the vial of "GRHL3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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