FSBP cdna clone
FSBP
Synonyms
FSBP; FSBP cdna clone
Form/Format
Lyophilized
Sequence
Nucleotide Sequence: ATGGTAGGAAAGGCTAGATCTTCCAATTTTACCTTATCCGAAAAGCTTGATTTGCTAAAGCTTGTGAAGCCATATGTGAAAATTCTCGAAGAACACACTAATAAACATTCAGTAATAGTAGAAAAGAATAGATGTTGGGATATCATAGCAGTTAACTATAATGCAATTGGAGTAGACCGCCCTCCTCGAACAGCACAGGGCCTACGCACCCTTTATAAAAGGCTCAAAGAATATGCCAAACAGGAGCTATTGCAGCAAAAAGAGACCCAATCAGATTTTAAAAGCAATATTTCTGAGCCAACCAAGAAAGTTATGGAGATGATTCCCCAGATTTCCAGTTTTTGCCTGGTAAGAGACAGGAACCACATACAAAGTGCAAACTTGGATGAGGAGGCACAGGCTGGTACCAGTTCACTACAGGTAATGTTGGATCACCATCCTGTTGCTATTACAGTGGAGGTGAAGCAAGAAGAAGACATTAAACCACCTCCTCCACTGGTTTTAAATTCTCAACAGAGTGATACTTTAGAGCAAAGAGAAGAACATGAATTAGTACATGTTATGGAAAGATCCTTGTCGCCTTCACTTTCCTCTGTTGATATGAGAATGACATCGTCTCCATCTTCTATTCCAAGGAGAGATGATTTTTTTCGGCATGAGAGTGGTGAACACTTTAGGTCACTATTAGGGTATGATCCTCAGATCCTGCAAATGTTGAAAGAGGAGCATCAGATAATTTTAGAAAATCAAAAAAATTTTGGATTGTATGTTCAGGAGAAGAGGGATGGATTGAAAAGAAGGCAGCAGCTAGAGGAAGAGCTACTAAGAGCAAAAATTGAAGTGGAGAAGCTGAAAGCAATTCGCTTACGGCATGATCTACCTGAATATAACAGTCTCTAA
Translation Sequence: MVGKARSSNF TLSEKLDLLK LVKPYVKILE EHTNKHSVIV EKNRCWDIIA VNYNAIGVDRPPRTAQGLRT LYKRLKEYAK QELLQQKETQ SDFKSNISEP TKKVMEMIPQ ISSFCLVRDRNHIQSANLDE EAQAGTSSLQ VMLDHHPVAI TVEVKQEEDI KPPPPLVLNS QQSDTLEQREEHELVHVMER SLSPSLSSVD MRMTSSPSSI PRRDDFFRHE SGEHFRSLLG YDPQILQMLKEEHQIILENQ KNFGLYVQEK RDGLKRRQQL EEELLRAKIE VEKLKAIRLR HDLPEYNSL
Translation Sequence: MVGKARSSNF TLSEKLDLLK LVKPYVKILE EHTNKHSVIV EKNRCWDIIA VNYNAIGVDRPPRTAQGLRT LYKRLKEYAK QELLQQKETQ SDFKSNISEP TKKVMEMIPQ ISSFCLVRDRNHIQSANLDE EAQAGTSSLQ VMLDHHPVAI TVEVKQEEDI KPPPPLVLNS QQSDTLEQREEHELVHVMER SLSPSLSSVD MRMTSSPSSI PRRDDFFRHE SGEHFRSLLG YDPQILQMLKEEHQIILENQ KNFGLYVQEK RDGLKRRQQL EEELLRAKIE VEKLKAIRLR HDLPEYNSL
Sequence Length
299
Species
Human
Chromosome Location
8q
OMIM Reference Number
616306
cDNA Size
900bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
Vector
(puc19-derived cloning vector)
Preparation Before Usage
1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.
Preparation and Storage
Store the plasmid at -20 degree C.
Related Product Information for FSBP cdna clone
Fibrinogen silencer-binding protein, also known as FSBP, is interacts with X11alpha. X11alpha/FSBP complex signals to the nucleus to repress glycogen synthase kinase-3beta promoter activity. X11alpha is a neuronal adaptor protein that interacts with the amyloid precursor protein (APP) through a centrally located phosphotyrosine binding domain to inhibit the production of Abeta peptide that is deposited in Alzheimer's disease brains.
Product Categories/Family for FSBP cdna clone
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
fibrinogen silencer-binding protein
UniProt Protein Name
Fibrinogen silencer-binding protein
Protein Family
UniProt Gene Name
FSBP
UniProt Entry Name
FSBP_HUMAN
Uniprot Description
FSBP: Transcriptional repressor that down-regulates the expression of the fibrinogen gamma chain. Represses transcription of GSK3B gene promoter via its interaction with APBA1. Interacts with APBA1 (via PDZ 1 and 2 domains). 2 isoforms of the human protein are produced by alternative splicing
Chromosomal Location of Human Ortholog: 8q22.1
Cellular Component: nucleus
Molecular Function: DNA helicase activity; DNA binding; DNA translocase activity; RNA helicase activity; ATP binding
Biological Process: mitotic recombination; meiotic recombination; DNA duplex unwinding; double-strand break repair via homologous recombination
Similar Products
Product Notes
The FSBP fsbp (Catalog #AAA201009) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Nucleotide Sequence: ATGGTAGGAA AGGCTAGATC TTCCAATTTT ACCTTATCCG AAAAGCTTGA TTTGCTAAAG CTTGTGAAGC CATATGTGAA AATTCTCGAA GAACACACTA ATAAACATTC AGTAATAGTA GAAAAGAATA GATGTTGGGA TATCATAGCA GTTAACTATA ATGCAATTGG AGTAGACCGC CCTCCTCGAA CAGCACAGGG CCTACGCACC CTTTATAAAA GGCTCAAAGA ATATGCCAAA CAGGAGCTAT TGCAGCAAAA AGAGACCCAA TCAGATTTTA AAAGCAATAT TTCTGAGCCA ACCAAGAAAG TTATGGAGAT GATTCCCCAG ATTTCCAGTT TTTGCCTGGT AAGAGACAGG AACCACATAC AAAGTGCAAA CTTGGATGAG GAGGCACAGG CTGGTACCAG TTCACTACAG GTAATGTTGG ATCACCATCC TGTTGCTATT ACAGTGGAGG TGAAGCAAGA AGAAGACATT AAACCACCTC CTCCACTGGT TTTAAATTCT CAACAGAGTG ATACTTTAGA GCAAAGAGAA GAACATGAAT TAGTACATGT TATGGAAAGA TCCTTGTCGC CTTCACTTTC CTCTGTTGAT ATGAGAATGA CATCGTCTCC ATCTTCTATT CCAAGGAGAG ATGATTTTTT TCGGCATGAG AGTGGTGAAC ACTTTAGGTC ACTATTAGGG TATGATCCTC AGATCCTGCA AATGTTGAAA GAGGAGCATC AGATAATTTT AGAAAATCAA AAAAATTTTG GATTGTATGT TCAGGAGAAG AGGGATGGAT TGAAAAGAAG GCAGCAGCTA GAGGAAGAGC TACTAAGAGC AAAAATTGAA GTGGAGAAGC TGAAAGCAAT TCGCTTACGG CATGATCTAC CTGAATATAA CAGTCTCTAA Tr anslation Sequence: MVGKARSSNF TLSEKLDLLK LVKPYVKILE EHTNKHSVIV EKNRCWDIIA VNYNAIGVDR PPRTAQGLRT LYKRLKEYAK QELLQQKETQ SDFKSNISEP TKKVMEMIPQ ISSFCLVRDR NHIQSANLDE EAQAGTSSLQ VMLDHHPVAI TVEVKQEEDI KPPPPLVLNS QQSDTLEQRE EHELVHVMER SLSPSLSSVD MRMTSSPSSI PRRDDFFRHE SGEHFRSLLG YDPQILQMLK EEHQIILENQ KNFGLYVQEK RDGLKRRQQL EEELLRAKIE VEKLKAIRLR HDLPEYNSL. It is sometimes possible for the material contained within the vial of "FSBP, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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