FGFRL1 cdna clone
FGFRL1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
FGFRL1: Has a negative effect on cell proliferation.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 4p16
Cellular Component: Golgi apparatus; plasma membrane; transport vesicle
Molecular Function: fibroblast growth factor receptor activity; heparin binding
Biological Process: fibroblast growth factor receptor signaling pathway; protein heterooligomerization; protein homooligomerization
Disease: Wolf-hirschhorn Syndrome
Research Articles on FGFRL1
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Product Notes
The FGFRL1 fgfrl1 (Catalog #AAA1265766) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgacgccga gccccctgtt gctgctcctg ctgccgccgc tgctgctggg ggccttcccg ccggccgccg ccgcccgagg ccccccaaag atggcggaca aggtggtccc acggcaggtg gcccggctgg gccgcactgt gcggctgcag tgcccagtgg agggggaccc gccgccgctg accatgtgga ccaaggatgg ccgcaccatc cacagcggct ggagccgctt ccgcgtgctg ccgcaggggc tgaaggtgaa gcaggtggag cgggaggatg ccggcgtgta cgtgtgcaag gccaccaacg gcttcggcag cctgagcgtc aactacaccc tcgtcgtgct ggatgacatt agcccaggga aggagagcct ggggcccgac agctcctctg ggggtcaaga ggaccccgcc agccagcagt gggcacgacc gcgcttcaca cagccctcca agatgaggcg ccgggtgatc gcacggcccg tgggtagctc cgtgcggctc aagtgcgtgg ccagcgggca ccctcggccc gacatcacgt ggatgaagga cgaccaggcc ttgacgcgcc cagaggccgc tgagcccagg aagaagaagt ggacactgag cctgaagaac ctgcggccgg aggacagcgg caaatacacc tgccgcgtgt cgaaccgcgc gggcgccatc aacgccacct acaaggtgga tgtgatccag cggacccgtt ccaagcccgt gctcacaggc acgcaccccg tgaacacgac ggtggacttc ggggggacca cgtccttcca gtgcaaggtg cgcagcgacg tgaagccggt gatccagtgg ctgaagcgcg tggagtacgg cgccgagggc cgccacaact ccaccatcga tgtgggcggc cagaagtttg tggtgctgcc cacgggtgac gtgtggtcgc ggcccgacgg ctcctacctc aataagctgc tcatcacccg tgcccgccag gacgatgcgg gcatgtacat ctgccttggc gccaacacca tgggctacag cttccgcagc gccttcctca ccgtgctgcc agacccaaaa ccgccagggc cacctgtggc ctcctcgtcc tcggccacta gcctgccgtg gcccgtggtc atcggcatcc cagccggcgc tgtcttcatc ctgggcaccc tgctcctgtg gctttgccag gcccagaaga agccgtgcac ccccgcgcct gcccctcccc tgcctgggca ccgcccgccg gggacggccc gcgaccgcag cggagacaag gaccttccct cgttggccgc cctcagcgct ggccctggtg tggggctgtg tgaggagcat gggtctccgg cagcccccca gcacttactg ggcccaggcc cagttgctgg ccctaagttg taccccaaac tctacacaga catccacaca cacacacaca cacactctca cacacactca cacgtggagg gcaaggtcca ccagcacatc cactatcagt gctag. It is sometimes possible for the material contained within the vial of "FGFRL1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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