FBXW2 cdna clone
FBXW2 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats. [provided by RefSeq, Jul 2008]
Uniprot Description
FBXW2: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 9q34
Molecular Function: protein binding; ubiquitin-protein ligase activity
Biological Process: protein modification process; proteolysis
Research Articles on FBXW2
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Product Notes
The FBXW2 fbxw2 (Catalog #AAA1276586) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggagagaa aggactttga gacatggctt gataacattt ctgttacatt tctttctctg acggacttgc agaaaaatga aactctggat cacctgatta gtctgagtgg ggcagtccag ctcaggcatc tctccaataa cctagagact ctcctcaagc gggacttcct caaactcctt cccctggagc tcagttttta tttgttaaaa tggctcgatc ctcagacttt actcacatgc tgcctcgtct ctaaacagtg gaataaggtg ataagtgcct gtacagaggt gtggcagact gcatgtaaaa atttgggctg gcagatagat gattctgttc aggacgcttt gcactggaag aaggtttatt tgaaggctat tttgagaatg aagcaactgg aggaccatga agcctttgaa acctcgtcat taattggaca cagtgccaga gtgtatgcac tttactacaa agatggactt ctctgtacag ggtcagatga cttgtctgca aagctgtggg atgtgagcac agggcagtgc gtttatggca tccagaccca cacttgtgca gcggtgaagt ttgatgaaca gaagcttgtg acaggctcct ttgacaacac tgtggcttgc tgggaatgga gttccggagc caggacccag cactttcggg ggcacacggg ggcggtattt agcgtggact acaatgatga actggatatc ttggtgagcg gctctgcaga cttcactgtg aaagtatggg ctttatctgc tgggacatgc ctgaacacac tcaccgggca cacggaatgg gtcaccaagg tagttttgca gaagtgcaaa gtcaagtctc tcttgcacag tcctggagac tacatcctct taagtgcaga caaatatgag attaagattt ggccaattgg gagagaaatc aactgtaagt gcttaaagac attgtctgtc tctgaggata gaagtatctg cctgcagcca agacttcatt ttgatggcaa atacattgtc tgtagttcag cacttggtct ctaccagtgg gactttgcca gttatgatat tctcagggtc atcaagactc ctgagatagc aaacttggcc ttgcttggct ttggagatat ctttgccctg ctgtttgaca accgctacct gtacatcatg gacttgcgga cagagagcct gattagtcgc tggcctctgc cagagtacag gaaatcaaag agaggctcaa gcttcctggc aggcgaagca tcctggctga atggactgga tgggcacaat gacacgggct tggtctttgc caccagcatg cctgaccaca gtattcacct ggtgttgtgg aaggagcacg gctga. It is sometimes possible for the material contained within the vial of "FBXW2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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