FBXO38 cdna clone
FBXO38 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a large protein that contains an F-box domain and may participate in protein ubiquitination. The encoded protein is a transcriptional co-activator of Krueppel-like factor 7 (Klf7). A heterozygous mutation in this gene was found in individuals with autosomal dominant distal hereditary motor neuronopathy type IID. There is a pseudogene for this gene on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Uniprot Description
FBX38: Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. May coactivate KLF7, but does not seem to promote KLF7 ubiquitination. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 5q32
Disease: Neuronopathy, Distal Hereditary Motor, Type Iid
Research Articles on FBXO38
Similar Products
Product Notes
The FBXO38 fbxo38 (Catalog #AAA1267754) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggggccac gaaagaaaag tgtgaaaaca tgtatcatga ataatgaaat tccagaagaa atgacagcag atgaaacaaa ggactatatg aatcaacttt cacatgaagt actttgccat atttttaggt acctccctct gcaggatatc atgtgtatgg aatgtctttc ccggaagcta aaggaagcag tgaccctata tctgcgagtt gtgagagttg tagatctctg tgcagggcgg tggtgggaat acatgccaag tggctttaca gatgccagtt ttctaacact attaaagaag atgccagatg ttgaacagct atatggcctt caccctcgat accttgagag gcgaagagta aggggccatg aggcttttag cattccagga gtcctagaag ctttgcagtc atgcccaaac ttagtgggtg tggaaacttc tcatttggag ttggtagaat ccatttggac atatatgccc catgttcata ttttggggaa atttcgtaat cgtaatggag cttttccaat tcctcctgaa aataaactga aaattcctat aggagccaaa attcaaactt tacatttagt tggggtgaat gttcctgaaa ttccttgtat cccaatgcta aggcaccttt atatgaagtg ggtaagactc actaaaccac agccatttaa agacttcctt tgtatcagct taagaacttt cgtcatgagg aactgtgcag gacccacaaa ttccttgaaa tatgtccctt tagtaacagg cttagcctct gcccgaaact tggaacactt agaaatggtt cgagttcctt tccttggagg tcttatccaa catgttgttg aagacagttg gagatcaggt ggttttagaa atttgcacac tattgttctg ggagcttgca aaaatgctct tgaagtagat cttggttacc tcatcattac tgctgcccgt aggttacatg aagttcggat ccagccttcc ctaaccaaag atggtgtctt ttctgcccta aagatggcag agttggagtt tccccagttt gaaacccttc atctaggata tgtagatgag tttttgctac agagcagaat ggctaatgcg gatctggtga agtatggttt ggctgatgtg gtagaaaatc ctggtatcat cactgatata gggatgaaag cagtcaatga agttttttcc tgtatcaaat atctggcaat ttacaattgc cctcatctac acaacccata caattggatc tcagaccact caagatggac tcgattggtt gatatcaacc tagtacggtg ccatgctttg aagctggact cttttggcca gtttattgaa ttattaccca gcctagagtt tatttcactg gatcagatgt ttcgtgaacc acccaagggt tgtgctcgag ttggtctgag tgcaggcgca ggaattggtg tttcatcagc tcttgttagc aaccagaact ccaacaatga cgaaaataat gcccagaata acaatgccaa catccacgac aacaatcacc atcatccaga tgactcagac gaggagaatg actttcggca agatctgcag ccaggagagc agcagtttgc agctgacgca ttaaatgaga tggaagacat cgtccaagaa gatggagagg tggtggccga gagtggaaat aatactccag ctcacagcca ggcaattatt cctgtggatg ttgatgagga acaagcagga cccagtggtc ttcagcgtgt agtaaaacca acctcaatta ctgttcatga ttcagagagt gatgatgaag aagatagtct agaactccaa gaagtctgga ttcctaagaa cggtactcgg cgttactctg aacgtgaaga aaaaactgga gagtcagtgc agtccagaga attgtcagta agtggaaaag gcaagactcc acttcgaaag aggtacaact cccatcagat gggccagtcg aagcagtttc ccctcgagga aagcagctgt gagaaaggct gtcaggtcac cagtgagcag atcaaagccg atatgaaagc agctagggat attcctgaaa agaaaaaaaa caaggatgtt tatcccagct gcagcagcac caccgccagc acagtgggaa actccagctc acacaacact gcttctcaaa gccccgactt tgtaaggacg gtgaacagcg gcggctcttc cgagcctagc cctacagaag tggatgtgtc caggcagtgt gcctgctccc ccggtgggtc agaggactct gaggccatgg aggagggaga tgcagagagt tctgtctgcc ccagatgctg ctgtcacagg ccccaggaat cccaaaggag aactagcagg tgttctgatg aggaacgtcc ttcaaccagc cgagcctgtg ttgtgaatgg cccggatgaa gtagccaaaa caaagccacg tcacgccatg aaacggaagc ggacagcaga taaatccact agtacaagtg atcctgtgat cgaggatgac catgtgcagg ttcttgtatt aaaatccaag aatcttgttg gagtcactat gaccaattgt ggaatcacag atctagtgct aaaagactgt ccaaagatga tgttcatcca tgctaccagg tgcagggtac taaaacattt aaaggtagaa aatgcaccaa ttgtaaaccg atttgactat gcacagtgca agaaactgaa catggatcag gtactagacc agatactaag aatgccaccc gagagaaacc gcatcatata cctacgccca atgcagcagg tggacactct aactttggag cagaagctat ttagtggtcc ctacccctat cacatctgta ttatccatga attcagtaac cctcccaatg tccggaataa ggtgcgcatt cgcagctgga tggacactat agcaaacatc aatcaagagc tcattaaata tgaattcttc cctgaagcca ctcgaagtga agaagactta aagaaatacc ccaagtaccc ctgggggaga gaaatctata ctttagaagg tgttgtggat ggagctccat attccatgat ttctgacttc ccttggctga ggtcattacg agctgcagag cccaacagct tcgctcgata cgactttgaa gacgatgaag aaagcactat ctatgctcct agaaggaaag gacagctgtc tgcagacatc tgtatggaaa caataggaga ggaaatttca gagatgcgtc agatgaagaa gggtgtattt cagcgagtag tggcaatttt tatccactat tgtgatgtca atggagagcc agttgaagat gactacattt aa. It is sometimes possible for the material contained within the vial of "FBXO38, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.