EPHB6 cdna clone
EPHB6 cDNA Clone
Gene Names
EPHB6; HEP
Synonyms
EPHB6; EPHB6 cDNA Clone; EPHB6 cdna clone
Sequence
ATGGTAGCTGTCGGGGGCTGCCGCTGCCAGCCTGGATACCAACCAGCACGAGGAGACAAGGCCTGCCAAGCCTGCCCACGGGGGCTCTATAAGTCTTCTGCTGGGAATGCTCCCTGCTCACCATGCCCTGCCCGCAGTCACGCTCCCAACCCAGCAGCCCCCGTTTGCCCCTGCCTGGAGGGCTTCTACCGGGCCAGTTCCGACCCACCAGAGGCCCCCTGCACTGGTCCTCCATCGGCTCCCCAGGAGCTTTGGTTTGAGGTGCAAGGCTCAGCACTCATGCTACACTGGCGCCTGCCTCGGGAGCTGGGGGGTCGAGGGGACCTGCTCTTCAATGTCGTGTGCAAGGAGTGTGAAGGCCGCCAGGAACCTGCCAGCGGTGGTGGGGGCACTTGTCACCGCTGCAGGGATGAGGTCCACTTCGACCCTCGCCAGAGAGGCCTGACTGAGAGCCGAGTGTTAGTGGGGGGACTCCGGGCACACGTACCCTACATCTTAGAGGTGCAGGCTGTTAATGGGGTGTCTGAGCTCAGCCCTGACCCTCCTCAGGCTGCAGCCATCAATGTCAGCACCAGCCATGAAGTGCCCTCTGCTGTCCCTGTGGTGCACCAGGTGAGCCGGGCATCCAACAGCATCACGGTGTCCTGGCCGCAGCCCGACCAGACCAATGGGAACATCCTGGACTATCAGCTCCGCTACTATGACCAGGCAGAAGACGAATCCCACTCCTTCACCCTGACCAGCGAGACCAACACTGCCACCGTGACACAGCTGAGCCCTGGCCACATCTATGGTTTCCAGGTGCGGGCCCGGACTGCTGCCGGCCACGGCCCCTACGGGGGCAAAGTCTATTTCCAGACACTTCCTCAAGGGGAGCTGTCTTCCCAGCTTCCGGAAAGACTCTCCTTGGTGATCGGCTCCATCCTGGGGGCTTTGGCCTTCCTCCTGCTGGCAGCCATCACCGTGCTGGCGGTCGTCTTCCAGCGGAAGCGGCGTGGGACTGGCTACACGGAGCAGCTGCAGCAATACAGCAGCCCAGGACTCGGGGTGAAGTATTACATCGACCCCTCCACCTACGAGGACCCCTGTCAGGCCATCCGAGAACTTGCCCGGGAAGTCGATCCTGCTTATATCAAGATTGAGGAGGTCATTGGGACAGGCTCTTTTGGAGAAGTGCGCCAGGGCCGCCTGCAGCCACGGGGACGGAGGGAGCAGACTGTGGCCATCCAGGCCCTGTGGGCCGGGGGCGCCGAAAGCCTGCAGATGACCTTCCTGGGCCGGGCCGCAGTGCTGGGTCAGTTCCAGCACCCCAACATCCTGCGGCTGGAGGGCGTGGTCACCAAGAGCCGACCCCTCATGGTGCTGACGGAGTTCATGGAGCTTGGCCCCCTGGACAGCTTCCTCAGGCAGCGGGAGGGCCAGTTCAGCAGCCTGCAGCTGGTGGCCATGCAGCGGGGAGTGGCTGCTGCCATGCAGTACCTGTCCAGCTTTGCCTTCGTCCATCGCTCGCTGTCTGCCCACAGCGTGCTGGTGAATAGCCACTTGGTGTGCAAGGTGGCCCGTCTTGGCCACAGTCCTCAGGGCCCAAGTTGTTTGCTTCGCTGGGCAGCCCCAGAGGTCATTGCACATGGAAAGCATACAACATCCAGTGATGTCTGGAGCTTTGGGATACTCATGTGGGAAGTGATGAGTTATGGAGAACGGCCTTACTGGGACATGAGTGAGCAGGAGGTACTAAATGCAATAGAGCAGGAGTTCCGGCTGCCCCCGCCTCCAGGCTGTCCTCCTGGATTACATCTACTTATGTTGGACACTTGGCAGAAGGACCGTGCCCGGCGGCCTCATTTTGACCAGCTGGTGGCTGCATTTGACAAGATGATCCGCAAGCCAGATACCCTGCAGGCTGGCGGGGACCCAGGGGAAAGGCCTTCCCAGGCCCTTCTGACCCCTGTGGCCCTGGACTTTCCTTGTCTGGACTCACCCCAGGCCTGGCTTTCAGCCATTGGACTGGAGTGCTACCAGGACAACTTCTCCAAGTTTGGCCTCTGTACCTTCAGTGATGTGGCTCAGCTCAGCCTAGAAGACCTGCCTGCCCTGGGCATCACCCTGGCTGGCCACCAGAAGAAGCTGCTGCACCACATCCAGCTCCTTCAGCAACACCTGAGGCAGCAGGGCTCAGTGGAGGTCTGA
Sequence Length
2190
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
57,498 Da
NCBI Official Full Name
Homo sapiens EPH receptor B6, mRNA
NCBI Official Synonym Full Names
EPH receptor B6
NCBI Official Symbol
EPHB6
NCBI Official Synonym Symbols
HEP
NCBI Protein Information
ephrin type-B receptor 6
UniProt Protein Name
Ephrin type-B receptor 6
Protein Family
UniProt Gene Name
EPHB6
UniProt Entry Name
EPHB6_HUMAN
NCBI Description
This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Uniprot Description
EphB6: Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T-cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2. Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Protein kinase, tyrosine (receptor); Membrane protein, integral; Protein kinase, TK; Kinase, protein; EC 2.7.10.1; TK group; Eph family
Chromosomal Location of Human Ortholog: 7q33-q35
Cellular Component: cytosol; extracellular region; plasma membrane
Molecular Function: receptor activity
Biological Process: ephrin receptor signaling pathway
Research Articles on EPHB6
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Product Notes
The EPHB6 ephb6 (Catalog #AAA1278484) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGTAGCTG TCGGGGGCTG CCGCTGCCAG CCTGGATACC AACCAGCACG AGGAGACAAG GCCTGCCAAG CCTGCCCACG GGGGCTCTAT AAGTCTTCTG CTGGGAATGC TCCCTGCTCA CCATGCCCTG CCCGCAGTCA CGCTCCCAAC CCAGCAGCCC CCGTTTGCCC CTGCCTGGAG GGCTTCTACC GGGCCAGTTC CGACCCACCA GAGGCCCCCT GCACTGGTCC TCCATCGGCT CCCCAGGAGC TTTGGTTTGA GGTGCAAGGC TCAGCACTCA TGCTACACTG GCGCCTGCCT CGGGAGCTGG GGGGTCGAGG GGACCTGCTC TTCAATGTCG TGTGCAAGGA GTGTGAAGGC CGCCAGGAAC CTGCCAGCGG TGGTGGGGGC ACTTGTCACC GCTGCAGGGA TGAGGTCCAC TTCGACCCTC GCCAGAGAGG CCTGACTGAG AGCCGAGTGT TAGTGGGGGG ACTCCGGGCA CACGTACCCT ACATCTTAGA GGTGCAGGCT GTTAATGGGG TGTCTGAGCT CAGCCCTGAC CCTCCTCAGG CTGCAGCCAT CAATGTCAGC ACCAGCCATG AAGTGCCCTC TGCTGTCCCT GTGGTGCACC AGGTGAGCCG GGCATCCAAC AGCATCACGG TGTCCTGGCC GCAGCCCGAC CAGACCAATG GGAACATCCT GGACTATCAG CTCCGCTACT ATGACCAGGC AGAAGACGAA TCCCACTCCT TCACCCTGAC CAGCGAGACC AACACTGCCA CCGTGACACA GCTGAGCCCT GGCCACATCT ATGGTTTCCA GGTGCGGGCC CGGACTGCTG CCGGCCACGG CCCCTACGGG GGCAAAGTCT ATTTCCAGAC ACTTCCTCAA GGGGAGCTGT CTTCCCAGCT TCCGGAAAGA CTCTCCTTGG TGATCGGCTC CATCCTGGGG GCTTTGGCCT TCCTCCTGCT GGCAGCCATC ACCGTGCTGG CGGTCGTCTT CCAGCGGAAG CGGCGTGGGA CTGGCTACAC GGAGCAGCTG CAGCAATACA GCAGCCCAGG ACTCGGGGTG AAGTATTACA TCGACCCCTC CACCTACGAG GACCCCTGTC AGGCCATCCG AGAACTTGCC CGGGAAGTCG ATCCTGCTTA TATCAAGATT GAGGAGGTCA TTGGGACAGG CTCTTTTGGA GAAGTGCGCC AGGGCCGCCT GCAGCCACGG GGACGGAGGG AGCAGACTGT GGCCATCCAG GCCCTGTGGG CCGGGGGCGC CGAAAGCCTG CAGATGACCT TCCTGGGCCG GGCCGCAGTG CTGGGTCAGT TCCAGCACCC CAACATCCTG CGGCTGGAGG GCGTGGTCAC CAAGAGCCGA CCCCTCATGG TGCTGACGGA GTTCATGGAG CTTGGCCCCC TGGACAGCTT CCTCAGGCAG CGGGAGGGCC AGTTCAGCAG CCTGCAGCTG GTGGCCATGC AGCGGGGAGT GGCTGCTGCC ATGCAGTACC TGTCCAGCTT TGCCTTCGTC CATCGCTCGC TGTCTGCCCA CAGCGTGCTG GTGAATAGCC ACTTGGTGTG CAAGGTGGCC CGTCTTGGCC ACAGTCCTCA GGGCCCAAGT TGTTTGCTTC GCTGGGCAGC CCCAGAGGTC ATTGCACATG GAAAGCATAC AACATCCAGT GATGTCTGGA GCTTTGGGAT ACTCATGTGG GAAGTGATGA GTTATGGAGA ACGGCCTTAC TGGGACATGA GTGAGCAGGA GGTACTAAAT GCAATAGAGC AGGAGTTCCG GCTGCCCCCG CCTCCAGGCT GTCCTCCTGG ATTACATCTA CTTATGTTGG ACACTTGGCA GAAGGACCGT GCCCGGCGGC CTCATTTTGA CCAGCTGGTG GCTGCATTTG ACAAGATGAT CCGCAAGCCA GATACCCTGC AGGCTGGCGG GGACCCAGGG GAAAGGCCTT CCCAGGCCCT TCTGACCCCT GTGGCCCTGG ACTTTCCTTG TCTGGACTCA CCCCAGGCCT GGCTTTCAGC CATTGGACTG GAGTGCTACC AGGACAACTT CTCCAAGTTT GGCCTCTGTA CCTTCAGTGA TGTGGCTCAG CTCAGCCTAG AAGACCTGCC TGCCCTGGGC ATCACCCTGG CTGGCCACCA GAAGAAGCTG CTGCACCACA TCCAGCTCCT TCAGCAACAC CTGAGGCAGC AGGGCTCAGT GGAGGTCTGA. It is sometimes possible for the material contained within the vial of "EPHB6, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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