EIF4E2 cdna clone
EIF4E2 cDNA Clone
NCBI and Uniprot Product Information
Uniprot Description
EIF4E2: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least eIF4A, eIF4E and eIF4G. eIF4E is also known to interact with other partners. EIF4E2 interacts with EIF4EBP1, EIF4EBP2 and EIF4EBP3 but not with eIF4G. Belongs to the eukaryotic initiation factor 4E family.
Protein type: Translation; Translation initiation
Chromosomal Location of Human Ortholog: 2q37.1
Cellular Component: cytosol; mRNA cap complex
Molecular Function: protein binding; RNA cap binding; translation factor activity, nucleic acid binding; ubiquitin protein ligase binding
Biological Process: negative regulation of translation
Research Articles on EIF4E2
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Product Notes
The EIF4E2 eif4e2 (Catalog #AAA1275067) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaacaaca agttcgacgc tttgaaagat gatgacagtg gggaccatga tcagaatgaa gaaaacagca cacagaaaga tggtgagaag gaaaaaacgg aacgagacaa gaatcagagc agtagcaaga gaaaggctgt tgtccctgga ccggcagagc atcccctgca gtacaactac actttttggt actccaggag aacccccggc cgtcccacga gctcacagag ctatgaacag aatatcaaac agattggcac ctttgcctct gtggagcagt tctggaggtt ttatagccac atggtacgtc ctggggacct gacaggccac agtgacttcc atctcttcaa agaaggaatt aaacccatgt gggaggatga tgcaaataaa aatggtggca agtggattat tcggctgcgg aagggcttgg cctcccgttg ctgggagaat ctcattttgg ccatgctggg ggaacagttc atggttgggg aggagatctg tggggctgtg gtgtctgtcc gctttcagga agacattatt tcaatatgga ataagactgc cagtgaccaa gcaaccacag cccgaatccg ggacacactt cggcgagtgc ttaacctacc tcccaacacc attatggaat acaaaactca caccgacagc atcaaaatgc caggcaggct gggcccccaa aggctccttt tttcaaaacc tctggaagcc gcggttgaat gtgccatgac cctctccctc tctggatggc accatcattg a. It is sometimes possible for the material contained within the vial of "EIF4E2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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