EEF2 cdna clone
EEF2 cDNA Clone
Gene Names
EEF2; EF2; EF-2; EEF-2; SCA26
Synonyms
EEF2; EEF2 cDNA Clone; EEF2 cdna clone
Sequence
atggtgaacttcacggtagaccagatccgcgccatcatggacaagaaggccaacatccgcaacatgtctgtcatcgcccacgtggaccatggcaagtccacgctgacagactccctggtgtgcaaggcgggcatcatcgcctcggcccgggccggggagacacgcttcactgatacccggaaggacgagcaggagcgttgcatcaccatcaagtcaactgccatctccctcttctacgagctctcggagaatgacttgaacttcatcaagcagagcaaggacggtgccggcttcctcatcaacctcattgactcccccgggcatgtcgacttctcctcggaggtgactgctgccctccgagtcaccgatggcgcattggtggtggtggactgcgtgtcaggcgtgtgcgtgcagacggagacagtgctgcggcaggccattgccgagcgcatcaagcctgtgctgatgatgaacaagatggaccgcgccctgctggagctgcagctggagcccgaggagctctaccagactttccagcgcatcgtggagaacgtgaacgtcatcatctccacctacggcgagggcgagagcggccccatgggcaacatcatgatcgatcctgtcctcggtaccgtgggctttgggtctggcctccacgggtgggccttcaccctgaagcagtttgccgagatgtatgtggccaagttcgccgccaagggggagggccagttggggcctgccgagcgggccaagaaagtagaggacatgatgaagaagctgtggggtgacaggtactttgacccagccaacggcaagttcagcaagtcagccaccagccccgaagggaagaagctgccacgcaccttctgccagctgatcctggaccccatcttcaaggtgtttgatgcgatcatgaatttcaagaaagaggagacagcaaaactgatagagaaactggacatcaaactggacagcgaggacaaggacaaagaaggcaaacccctgctgaaggctgtgatgcgccgctggctgcctgccggagacgccttgttgcagatgatcaccatccacctgccctcccctgtgacggcccagaagtaccgctgcgagctcctgtacgaggggcccccggacgacgaggctgccatgggcattaaaagctgtgaccccaaaggccctcttatgatgtatatttccaaaatggtgccaacctccgacaaaggtcggttctacgcctttggacgagtcttctcggggctggtctccactggcctgaaggtcaggatcatggggcccaactatacccctgggaagaaggaggacctctacctgaagccaatccagagaacaatcttgatgatgggccgctacgtggagcccatcgaggatgtgccttgtgggaacattgtgggcctcgtgggcgtggaccagttcctggtgaagacgggcaccatcaccaccttcgagcacgcgcacaacatgcgggtgatgaagttcagcgtcagccctgttgtcagagtggccgtggaggccaagaacccggctgacctgcccaagctggtggaggggctgaagcggctggccaagtccgaccccatggtgcagtgcatcatcgaggagtcgggagagcacatcatcgcgggcgccggcgagctgcacctggagatctgcctgaaggacctggaggaggaccacgcctgcatccccatcaagaaatctgacccggtcgtctcgtaccgcgagacggtcagtgaagagtcgaacgtgctctgcctctccaagtcccccaacaagcacaaccggctgtacatgaaggcgcggcccttccccgacggcctggccgaggacatcgataaaggcgaggtgtccgcccgtcaggagctcaagcagcgggcgcgctacctggccgagaagtacgagtgggacgtggctgaggcccgcaagatctggtgctttgggcccgacggcaccggccccaacatcctcaccgacatcaccaagggtgtgcagtacctcaacgagatcaaggacagtgtggtggccggcttccagtgggccaccaaggagggcgcactgtgtgaggagaacatgcggggtgtgcgcttcgacgtccacgacgtcaccctgcacgccgacgccatccaccgcggagggggccagatcatccccacagcacggcgctgcctctacgccagtgtgctgaccgcccagccacgcctcatggagcccatctaccttgtggagatccagtgtccagagcaggtggtcggtggcatctacggggttttgaacaggaagcggggccacgtgttcgaggagtcccaggtggccggcacccccatgtttgtggtcaaggcctatctgcccgtcaacgagtcctttggcttcaccgctgacctgaggtccaacacgggcggccaggcgttcccccagtgtgtgtttgaccactggcagatcctgcccggagaccccttcgacaacagcagccgccccagccaggtggtggcggagacccgcaagcgcaagggcctgaaagaaggcatccctgccctggacaacttcctggacaaattgtag
Sequence Length
2577
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
95,338 Da
NCBI Official Full Name
Homo sapiens eukaryotic translation elongation factor 2, mRNA
NCBI Official Synonym Full Names
eukaryotic translation elongation factor 2
NCBI Official Symbol
EEF2
NCBI Official Synonym Symbols
EF2; EF-2; EEF-2; SCA26
NCBI Protein Information
elongation factor 2
UniProt Protein Name
Elongation factor 2
Protein Family
UniProt Gene Name
EEF2
UniProt Synonym Gene Names
EF2; EF-2
UniProt Entry Name
EF2_HUMAN
NCBI Description
This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008]
Uniprot Description
EEF2: a member of the GTP-binding translation elongation factor family. An essential factor for protein synthesis. Promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by eEF2 kinase phosphorylation. eEF2 kinase is normally dependent on Ca2+ ions and calmodulin. eEF2 kinase can also be activated by PKA in response to elevated cAMP levels, which are generally increased in stress- or starvation-related conditions. A variety of treatments known to raise intracellular Ca2+ or cAMP levels have been shown to result in increased phosphorylation of eEF2, and thus to inhibit peptide-chain elongation.
Protein type: Translation; Translation elongation
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: cell-cell adherens junction; cytoplasm; cytosol; extracellular matrix; membrane; nucleus; plasma membrane; ribonucleoprotein complex
Molecular Function: GTPase activity; protein binding; protein kinase binding
Biological Process: peptidyl-diphthamide biosynthetic process from peptidyl-histidine; positive regulation of translation; translational elongation
Disease: Spinocerebellar Ataxia 26
Research Articles on EEF2
Similar Products
Product Notes
The EEF2 eef2 (Catalog #AAA1274810) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggtgaact tcacggtaga ccagatccgc gccatcatgg acaagaaggc caacatccgc aacatgtctg tcatcgccca cgtggaccat ggcaagtcca cgctgacaga ctccctggtg tgcaaggcgg gcatcatcgc ctcggcccgg gccggggaga cacgcttcac tgatacccgg aaggacgagc aggagcgttg catcaccatc aagtcaactg ccatctccct cttctacgag ctctcggaga atgacttgaa cttcatcaag cagagcaagg acggtgccgg cttcctcatc aacctcattg actcccccgg gcatgtcgac ttctcctcgg aggtgactgc tgccctccga gtcaccgatg gcgcattggt ggtggtggac tgcgtgtcag gcgtgtgcgt gcagacggag acagtgctgc ggcaggccat tgccgagcgc atcaagcctg tgctgatgat gaacaagatg gaccgcgccc tgctggagct gcagctggag cccgaggagc tctaccagac tttccagcgc atcgtggaga acgtgaacgt catcatctcc acctacggcg agggcgagag cggccccatg ggcaacatca tgatcgatcc tgtcctcggt accgtgggct ttgggtctgg cctccacggg tgggccttca ccctgaagca gtttgccgag atgtatgtgg ccaagttcgc cgccaagggg gagggccagt tggggcctgc cgagcgggcc aagaaagtag aggacatgat gaagaagctg tggggtgaca ggtactttga cccagccaac ggcaagttca gcaagtcagc caccagcccc gaagggaaga agctgccacg caccttctgc cagctgatcc tggaccccat cttcaaggtg tttgatgcga tcatgaattt caagaaagag gagacagcaa aactgataga gaaactggac atcaaactgg acagcgagga caaggacaaa gaaggcaaac ccctgctgaa ggctgtgatg cgccgctggc tgcctgccgg agacgccttg ttgcagatga tcaccatcca cctgccctcc cctgtgacgg cccagaagta ccgctgcgag ctcctgtacg aggggccccc ggacgacgag gctgccatgg gcattaaaag ctgtgacccc aaaggccctc ttatgatgta tatttccaaa atggtgccaa cctccgacaa aggtcggttc tacgcctttg gacgagtctt ctcggggctg gtctccactg gcctgaaggt caggatcatg gggcccaact atacccctgg gaagaaggag gacctctacc tgaagccaat ccagagaaca atcttgatga tgggccgcta cgtggagccc atcgaggatg tgccttgtgg gaacattgtg ggcctcgtgg gcgtggacca gttcctggtg aagacgggca ccatcaccac cttcgagcac gcgcacaaca tgcgggtgat gaagttcagc gtcagccctg ttgtcagagt ggccgtggag gccaagaacc cggctgacct gcccaagctg gtggaggggc tgaagcggct ggccaagtcc gaccccatgg tgcagtgcat catcgaggag tcgggagagc acatcatcgc gggcgccggc gagctgcacc tggagatctg cctgaaggac ctggaggagg accacgcctg catccccatc aagaaatctg acccggtcgt ctcgtaccgc gagacggtca gtgaagagtc gaacgtgctc tgcctctcca agtcccccaa caagcacaac cggctgtaca tgaaggcgcg gcccttcccc gacggcctgg ccgaggacat cgataaaggc gaggtgtccg cccgtcagga gctcaagcag cgggcgcgct acctggccga gaagtacgag tgggacgtgg ctgaggcccg caagatctgg tgctttgggc ccgacggcac cggccccaac atcctcaccg acatcaccaa gggtgtgcag tacctcaacg agatcaagga cagtgtggtg gccggcttcc agtgggccac caaggagggc gcactgtgtg aggagaacat gcggggtgtg cgcttcgacg tccacgacgt caccctgcac gccgacgcca tccaccgcgg agggggccag atcatcccca cagcacggcg ctgcctctac gccagtgtgc tgaccgccca gccacgcctc atggagccca tctaccttgt ggagatccag tgtccagagc aggtggtcgg tggcatctac ggggttttga acaggaagcg gggccacgtg ttcgaggagt cccaggtggc cggcaccccc atgtttgtgg tcaaggccta tctgcccgtc aacgagtcct ttggcttcac cgctgacctg aggtccaaca cgggcggcca ggcgttcccc cagtgtgtgt ttgaccactg gcagatcctg cccggagacc ccttcgacaa cagcagccgc cccagccagg tggtggcgga gacccgcaag cgcaagggcc tgaaagaagg catccctgcc ctggacaact tcctggacaa attgtag. It is sometimes possible for the material contained within the vial of "EEF2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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