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DNAJC24 cdna clone

DNAJC24

Gene Names
DNAJC24; DPH4; JJJ3; ZCSL3
Synonyms
DNAJC24; DPH4; JJJ3; ZCSL3; DNAJC24 cdna clone
Ordering
For Research Use Only!
Form/Format
Lyophilized
Sequence
Nucleotide Sequence: ATGATGGCGGTTGAGCAGATGCCAAAAAAGGATTGGTACAGCATCCTGGGAGCAGACCCATCTGCAAATATATCAGACCTAAAACAAAAATATCAAAAACTCATATTAATGTATCATCCAGATAAACAAAGTACAGATGTACCAGCAGGAACAGTGGAGGAATGTGTACAGAAGTTCATCGAAATTGATCAAGCATGGAAAATTCTAGGAAATGAAGAGACAAAAAGAGAGTATGACCTGCAGCGGTGTGAAGATGATCTAAGAAATGTAGGACCAGTAGATGCTCAAGTATATCTTGAAGAAATGTCTTGGAATGAAGGTGATCACTCTTTTTATCTGAGTTGCAGATGTGGTGGAAAATACAGTGTTTCCAAGGATGAAGCGGAAGAAGTTAGCCTGATTTCTTGTGATACATGTTCACTAATTATAGAACTCCTTCATTATAACTAA

Translation Sequence: MMAVEQMPKK DWYSILGADP SANISDLKQK YQKLILMYHP DKQSTDVPAG TVEECVQKFIEIDQAWKILG NEETKREYDL QRCEDDLRNV GPVDAQVYLE EMSWNEGDHS FYLSCRCGGKYSVSKDEAEE VSLISCDTCS LIIELLHYN
Sequence Length
149
Species
Human
Chromosome Location
11p13
OMIM Reference Number
611072
cDNA Size
450bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
Vector
(puc19-derived cloning vector)
Preparation Before Usage
1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.
Preparation and Storage
Store the plasmid at -20 degree C.
Related Product Information for DNAJC24 cdna clone
DnaJ homolog subfamily C member 24, also known as DNAJC24, is a member of the ZCSL family of proteins and each contain one DPH-type zinc finger. This enzyme is involved in the synthesis of diphthamide, a protein found on translation elongation factor EF-2 that is the target of bacterial ADP-ribosylating toxins. DNAJC24 stimulates the ATPase activity of several Hsp70-type chaperones. It is detected in heart, brain, spleen, lung, liver, kidney and testis.
Product Categories/Family for DNAJC24 cdna clone

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
dnaJ homolog subfamily C member 24
NCBI Official Synonym Full Names
DnaJ heat shock protein family (Hsp40) member C24
NCBI Official Symbol
DNAJC24
NCBI Official Synonym Symbols
DPH4; JJJ3; ZCSL3
NCBI Protein Information
dnaJ homolog subfamily C member 24
UniProt Protein Name
DnaJ homolog subfamily C member 24
Protein Family
UniProt Gene Name
DNAJC24
UniProt Synonym Gene Names
DPH4; ZCSL3
UniProt Entry Name
DJC24_HUMAN

NCBI Description

Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008]

Uniprot Description

DNAJC24: Stimulates the ATPase activity of several Hsp70-type chaperones. Belongs to the DPH4 family.

Protein type: Enzyme, misc.; Chaperone

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: cytoskeleton; cytoplasm

Molecular Function: ATPase activator activity; zinc ion binding; ferrous iron binding

Biological Process: positive regulation of ATPase activity; peptidyl-diphthamide biosynthetic process from peptidyl-histidine

Research Articles on DNAJC24

Similar Products

Product Notes

The DNAJC24 dnajc24 (Catalog #AAA200983) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Nucleotide Sequence: ATGATGGCGG TTGAGCAGAT GCCAAAAAAG GATTGGTACA GCATCCTGGG AGCAGACCCA TCTGCAAATA TATCAGACCT AAAACAAAAA TATCAAAAAC TCATATTAAT GTATCATCCA GATAAACAAA GTACAGATGT ACCAGCAGGA ACAGTGGAGG AATGTGTACA GAAGTTCATC GAAATTGATC AAGCATGGAA AATTCTAGGA AATGAAGAGA CAAAAAGAGA GTATGACCTG CAGCGGTGTG AAGATGATCT AAGAAATGTA GGACCAGTAG ATGCTCAAGT ATATCTTGAA GAAATGTCTT GGAATGAAGG TGATCACTCT TTTTATCTGA GTTGCAGATG TGGTGGAAAA TACAGTGTTT CCAAGGATGA AGCGGAAGAA GTTAGCCTGA TTTCTTGTGA TACATGTTCA CTAATTATAG AACTCCTTCA TTATAACTAA Tr anslation Sequence: MMAVEQMPKK DWYSILGADP SANISDLKQK YQKLILMYHP DKQSTDVPAG TVEECVQKFI EIDQAWKILG NEETKREYDL QRCEDDLRNV GPVDAQVYLE EMSWNEGDHS FYLSCRCGGK YSVSKDEAEE VSLISCDTCS LIIELLHYN. It is sometimes possible for the material contained within the vial of "DNAJC24, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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