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DECR2 cdna clone

DECR2

Gene Names
DECR2; PDCR; SDR17C1
Synonyms
DECR2; PDCR; SDR17C1; DECR2 cdna clone
Ordering
For Research Use Only!
Form/Format
Lyophilized
Sequence
Nucleotide Sequence: ATGGCCCAGCCGCCGCCCGACGTGGAGGGGGACGACTGTCTCCCCGCGTACCGCCACCTCTTCTGCCCGGACCTGCTGCGGGACAAAGTGGCCTTCATCACAGGAGGCGGCTCTGGGATTGGGTTCCGGATTGCTGAGATTTTCATGCGGCACGGCTGCCATACGGTGATTGCCAGTAGGAGCCTGCCGCGAGTGCTGACGGCCGCCAGGAAGCTGGCTGGGGCCACCGGCCGGCGCTGCCTCCCTCTCTCTATGGACGTCCGAGCGCCCCCAGCTGTCATGGCCGCCGTGGACCAGGCTCTGAAGGAGTTTGGCAGAATCGACATTCTCATTAACTGTGCGGCCGGGAACTTCCTGTGCCCCGCTGGCGCCTTGTCCTTCAACGCCTTCAAGACCGTGATGGACATCGATACCAGCGGCACCTTCAATGTGTCTCGTGTGCTCTATGAGAAGTTCTTCCGGGACCACGGAGGGGTGATCGTGAACATCACTGCCACCCTGGGGAACCGGGGGCAGGCGCTCCAGGTGCATGCAGGCTCCGCCAAGGCCGCTGTGGACGCGATGACGCGGCACTTGGCTGTGGAGTGGGGTCCCCAAAACATCCGCGTCAACAGCCTCGCCCCTGGCCCCATCAGTGGCACAGAGGGGCTCCGGCGACTGGGTGGCCCTCAGGCCAGCCTGAGCACCAAGGTCACTGCCAGCCCGCTGCAGAGGCTGGGGAACAAGACCGAGATCGCCCACAGCGTGCTCTACCTGGCCAGCCCTCTGGCTTCCTACGTGACGGGGGCCGTGCTGGTGGCCGATGGCGGGGCATGGTTGACGTTCCCAAACGGTGTCAAAGGGCTGCCGGATTTCGCATCCTTCTCTGCTAAGCTCTAG

Translation Sequence: MAQPPPDVEG DDCLPAYRHL FCPDLLRDKV AFITGGGSGI GFRIAEIFMR HGCHTVIASRSLPRVLTAAR KLAGATGRRC LPLSMDVRAP PAVMAAVDQA LKEFGRIDIL INCAAGNFLCPAGALSFNAF KTVMDIDTSG TFNVSRVLYE KFFRDHGGVI VNITATLGNR GQALQVHAGSAKAAVDAMTR HLAVEWGPQN IRVNSLAPGP ISGTEGLRRL GGPQASLSTK VTASPLQRLGNKTEIAHSVL YLASPLASYV TGAVLVADGG AWLTFPNGVK GLPDFASFSA KL
Sequence Length
292
Species
Human
Chromosome Location
16p13.3
OMIM Reference Number
615839
cDNA Size
879bp
Vector Description
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.
Vector
(puc19-derived cloning vector)
Preparation Before Usage
1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.
Preparation and Storage
Store the plasmid at -20 degree C.
Related Product Information for DECR2 cdna clone
Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2, 4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2, 4-dienoyl-CoAs, but also towards 2, 4, 7, 10, 13, 16, 19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
Product Categories/Family for DECR2 cdna clone

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
peroxisomal 2,4-dienoyl-CoA reductase
NCBI Official Synonym Full Names
2,4-dienoyl-CoA reductase 2
NCBI Official Symbol
DECR2
NCBI Official Synonym Symbols
PDCR; SDR17C1
NCBI Protein Information
peroxisomal 2,4-dienoyl-CoA reductase
UniProt Protein Name
Peroxisomal 2,4-dienoyl-CoA reductase
UniProt Gene Name
DECR2
UniProt Synonym Gene Names
PDCR; pDCR
UniProt Entry Name
DECR2_HUMAN

Uniprot Description

DECR2: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19- docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Oxidoreductase; EC 1.3.1.34

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: peroxisomal membrane

Molecular Function: 2,4-dienoyl-CoA reductase (NADPH) activity; receptor binding; trans-2-enoyl-CoA reductase (NADPH) activity

Biological Process: unsaturated fatty acid biosynthetic process

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Product Notes

The DECR2 decr2 (Catalog #AAA200762) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Nucleotide Sequence: ATGGCCCAGC CGCCGCCCGA CGTGGAGGGG GACGACTGTC TCCCCGCGTA CCGCCACCTC TTCTGCCCGG ACCTGCTGCG GGACAAAGTG GCCTTCATCA CAGGAGGCGG CTCTGGGATT GGGTTCCGGA TTGCTGAGAT TTTCATGCGG CACGGCTGCC ATACGGTGAT TGCCAGTAGG AGCCTGCCGC GAGTGCTGAC GGCCGCCAGG AAGCTGGCTG GGGCCACCGG CCGGCGCTGC CTCCCTCTCT CTATGGACGT CCGAGCGCCC CCAGCTGTCA TGGCCGCCGT GGACCAGGCT CTGAAGGAGT TTGGCAGAAT CGACATTCTC ATTAACTGTG CGGCCGGGAA CTTCCTGTGC CCCGCTGGCG CCTTGTCCTT CAACGCCTTC AAGACCGTGA TGGACATCGA TACCAGCGGC ACCTTCAATG TGTCTCGTGT GCTCTATGAG AAGTTCTTCC GGGACCACGG AGGGGTGATC GTGAACATCA CTGCCACCCT GGGGAACCGG GGGCAGGCGC TCCAGGTGCA TGCAGGCTCC GCCAAGGCCG CTGTGGACGC GATGACGCGG CACTTGGCTG TGGAGTGGGG TCCCCAAAAC ATCCGCGTCA ACAGCCTCGC CCCTGGCCCC ATCAGTGGCA CAGAGGGGCT CCGGCGACTG GGTGGCCCTC AGGCCAGCCT GAGCACCAAG GTCACTGCCA GCCCGCTGCA GAGGCTGGGG AACAAGACCG AGATCGCCCA CAGCGTGCTC TACCTGGCCA GCCCTCTGGC TTCCTACGTG ACGGGGGCCG TGCTGGTGGC CGATGGCGGG GCATGGTTGA CGTTCCCAAA CGGTGTCAAA GGGCTGCCGG ATTTCGCATC CTTCTCTGCT AAGCTCTAG< br> Tra nslation Sequence: MAQPPPDVEG DDCLPAYRHL FCPDLLRDKV AFITGGGSGI GFRIAEIFMR HGCHTVIASR SLPRVLTAAR KLAGATGRRC LPLSMDVRAP PAVMAAVDQA LKEFGRIDIL INCAAGNFLC PAGALSFNAF KTVMDIDTSG TFNVSRVLYE KFFRDHGGVI VNITATLGNR GQALQVHAGS AKAAVDAMTR HLAVEWGPQN IRVNSLAPGP ISGTEGLRRL GGPQASLSTK VTASPLQRLG NKTEIAHSVL YLASPLASYV TGAVLVADGG AWLTFPNGVK GLPDFASFSA KL. It is sometimes possible for the material contained within the vial of "DECR2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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