CSPP1 cdna clone
CSPP1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a centrosome and spindle pole associated protein. The encoded protein plays a role in cell-cycle progression and spindle organization, regulates cytokinesis, interacts with Nephrocystin 8 and is required for cilia formation. Mutations in this gene result in primary cilia abnormalities and classical Joubert syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Apr 2014]
Uniprot Description
CSPP1: May play a role in cell-cycle-dependent microtubule organization. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 8q13.2
Cellular Component: centrosome; microtubule organizing center; spindle; spindle pole
Biological Process: positive regulation of cell division; positive regulation of cytokinesis
Disease: Joubert Syndrome 21
Research Articles on CSPP1
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Product Notes
The CSPP1 cspp1 (Catalog #AAA1274924) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggctgata atttggatga atttattgaa gagcaaaaag ccagattggc cgaagacaaa gcagagttgg aaagtgatcc accttacatg gaaatgaagg gaaagttgtc agcgaagctt tctgaaaaca gtaagatact gatctctatg gctaaggaaa acataccacc aaatagtcaa cagaccaggg gttccttagg aattgattat ggattaagtt taccacttgg agaagactat gaacggaaga aacataaatt aaaagaagaa ttgcggcaag attacagacg ttatcttact caggaaaggt tgaaacttga acgtaacaaa gaatacaatc agtttctcag gggtaaggaa gaatccagtg aaaagttcag gcaggtggaa aagagtactg agcccaagag tcagagaaat aaaaaaccta ttggtcaagt taagcctgat ctaacttcac aaatacagac atcttgtgaa aattcagagg gtcctagaaa agatgtctta actccttcag aggcatatga agaacttctg aaccaaagac gactagagga ggacagatac cgacaactag atgatgaaat cgaattaagg aatagaagaa ttattaaaag caaatga. It is sometimes possible for the material contained within the vial of "CSPP1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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