CNKSR1 cdna clone
CNKSR1 cDNA Clone
Gene Names
CNKSR1; CNK; CNK1
Synonyms
CNKSR1; CNKSR1 cDNA Clone; CNKSR1 cdna clone
Sequence
atggaaccggtagagacctggacccccggaaaggtggcaacttggctgagaggtcttgacgactccctgcaggactatccctttgaggactggcagctgcctggcaagaacctgctccagctctgcccccaaagcctcgaggctctggctgtgcggtctctgggacaccaggagctcatcctgggcggggtggaacagctccaggccctgagctccaggctacagacagagaacctgcaaagcctgacagagggacttctgggggcaacccatgacttccagagcatagtccaaggctgcctgggggactgtgccaagacccctattgatgtcctctgtgcagctgtggagctgttgcatgaagctgacgccctcctcttctggctcagcaggtacctcttctcccacttaaatgatttctcagcatgccaggagatccgagacttgttggaggagctgagccaggtcttgcatgaggatggtccagcggctgagaaggagggcacagtcctgaggatctgcagccacgtggctgggatctgccacaacatcctggtctgctgccccaaggagctgctggaacagaaggccgtgctcgagcaggtgcagctggacagtccattgggcctagaaattcacaccaccagcaattgccagcactttgtgtcccaagtggacacccaggttcccactgactcccgactgcagatccagcctggagacgaggttgtccagatcaacgagcaggtggtggtgcgtgaggagagggacatggtgggatggccccgtaagaacatggtgagggaactgctgcgggagccagccggactcagcttagtgctgaagaagatcccgataccggagacccccccacagacgccccctcaggtcctggactccccgcaccagaggagcccatcactgtctctggccccactgtctcccagggccccatctgaagacgtctttgcctttgacctgtcttcaaaccccagtcccggacccagccctgcctggacagactctgcctcccttggccctgagcccctgcccatccccccggaacccccagccatactcccagcaggggtagcagggactccagggctccctgaatcccctgacaagagtcctgttggtcggaagaaatcaaaaggcctggcgacccggctgagccgccggcgggtgtcatgccgtgagctgggccggccggactgtgacggctggctcctgttgcgaaaggcaccgggcggcttcatgggcccgcgctggcgccgccgctggtttgtgctcaagggacacacgctctactggtaccgccagccccaggatgagaaggctgagggcctcatcaatgtctccaactatagtctggaaagtggacatgatcagaagaagaaatatgtgtttcagctcacccatgatgtgtacaaacccttcatcttcgctgctgataccctgacagatctgagcatgtgggtgcgtcatctcattacctgcatctccaagtaccagtctccaggccgggcccccccaccccgagaggaagactgctacagtgagaccgaagcagaggacccggacgatgaggctgggtcccactcagcctcgcccagccctgctcaagctgggagtcccctccatggagacacatcacctgcagccacccccacacagcgcagcccacggacctcctttggctctctgacagacagcagtgaagaggcactggaaggaatggtacgggggctgaggcagggtggcgtgtccctcctaggccagccacagcccctgacccaggaacagtggcggagctctttcatgcggcgcaaccgagaccctcagctcaatgagcgagtgcaccgtgtgcgggcgctacagagcacactcaaggcaaagctgcaggagctgcaggtcctagaagaagtgctgggtgaccctgagctgacaggagagaagttccgccagtggaaggagcagaaccgggagctgtactcagagggcctgggggcctggggagtggcacaggctgaaggcagctcccacatcttgacctctgactccacagaacagtccccccactccctgccctctgaccctgaagagcactcccatctctgccccctgacctcagagagcagcctccgacctcctgacctctga
Sequence Length
2163
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
78,790 Da
NCBI Official Full Name
Homo sapiens connector enhancer of kinase suppressor of Ras 1, mRNA
NCBI Official Synonym Full Names
connector enhancer of kinase suppressor of Ras 1
NCBI Official Symbol
CNKSR1
NCBI Official Synonym Symbols
CNK; CNK1
NCBI Protein Information
connector enhancer of kinase suppressor of ras 1
UniProt Protein Name
Connector enhancer of kinase suppressor of ras 1
Protein Family
UniProt Gene Name
CNKSR1
UniProt Synonym Gene Names
CNK1; Connector enhancer of KSR 1; CNK1; hCNK1
UniProt Entry Name
CNKR1_HUMAN
NCBI Description
This gene encodes a protein containing several motifs involved in protein-protein interaction, including PDZ, PH (Pleckstrin homology), and SAM (sterile alpha motif) domains. The encoded protein acts as a scaffold component for receptor tyrosine kinase signaling and may mediate crosstalk between different signaling pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Uniprot Description
CNK1: a RAF-binding multidomain protein required for RAS signaling. Contains several protein-protein interaction domains. Its PH domain interacts with Rho in a GTP-dependent manner. Associates with Rhophilin and RalGDS, Rho and Ras effector molecules. Two alternatively spliced isoforms have been described.
Protein type: G protein regulator, misc.; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 1p36.11
Cellular Component: cell cortex; intercellular junction; plasma membrane
Molecular Function: protein binding; protein binding, bridging
Biological Process: Ras protein signal transduction; Rho protein signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway
Research Articles on CNKSR1
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Product Notes
The CNKSR1 cnksr1 (Catalog #AAA1278677) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggaaccgg tagagacctg gacccccgga aaggtggcaa cttggctgag aggtcttgac gactccctgc aggactatcc ctttgaggac tggcagctgc ctggcaagaa cctgctccag ctctgccccc aaagcctcga ggctctggct gtgcggtctc tgggacacca ggagctcatc ctgggcgggg tggaacagct ccaggccctg agctccaggc tacagacaga gaacctgcaa agcctgacag agggacttct gggggcaacc catgacttcc agagcatagt ccaaggctgc ctgggggact gtgccaagac ccctattgat gtcctctgtg cagctgtgga gctgttgcat gaagctgacg ccctcctctt ctggctcagc aggtacctct tctcccactt aaatgatttc tcagcatgcc aggagatccg agacttgttg gaggagctga gccaggtctt gcatgaggat ggtccagcgg ctgagaagga gggcacagtc ctgaggatct gcagccacgt ggctgggatc tgccacaaca tcctggtctg ctgccccaag gagctgctgg aacagaaggc cgtgctcgag caggtgcagc tggacagtcc attgggccta gaaattcaca ccaccagcaa ttgccagcac tttgtgtccc aagtggacac ccaggttccc actgactccc gactgcagat ccagcctgga gacgaggttg tccagatcaa cgagcaggtg gtggtgcgtg aggagaggga catggtggga tggccccgta agaacatggt gagggaactg ctgcgggagc cagccggact cagcttagtg ctgaagaaga tcccgatacc ggagaccccc ccacagacgc cccctcaggt cctggactcc ccgcaccaga ggagcccatc actgtctctg gccccactgt ctcccagggc cccatctgaa gacgtctttg cctttgacct gtcttcaaac cccagtcccg gacccagccc tgcctggaca gactctgcct cccttggccc tgagcccctg cccatccccc cggaaccccc agccatactc ccagcagggg tagcagggac tccagggctc cctgaatccc ctgacaagag tcctgttggt cggaagaaat caaaaggcct ggcgacccgg ctgagccgcc ggcgggtgtc atgccgtgag ctgggccggc cggactgtga cggctggctc ctgttgcgaa aggcaccggg cggcttcatg ggcccgcgct ggcgccgccg ctggtttgtg ctcaagggac acacgctcta ctggtaccgc cagccccagg atgagaaggc tgagggcctc atcaatgtct ccaactatag tctggaaagt ggacatgatc agaagaagaa atatgtgttt cagctcaccc atgatgtgta caaacccttc atcttcgctg ctgataccct gacagatctg agcatgtggg tgcgtcatct cattacctgc atctccaagt accagtctcc aggccgggcc cccccacccc gagaggaaga ctgctacagt gagaccgaag cagaggaccc ggacgatgag gctgggtccc actcagcctc gcccagccct gctcaagctg ggagtcccct ccatggagac acatcacctg cagccacccc cacacagcgc agcccacgga cctcctttgg ctctctgaca gacagcagtg aagaggcact ggaaggaatg gtacgggggc tgaggcaggg tggcgtgtcc ctcctaggcc agccacagcc cctgacccag gaacagtggc ggagctcttt catgcggcgc aaccgagacc ctcagctcaa tgagcgagtg caccgtgtgc gggcgctaca gagcacactc aaggcaaagc tgcaggagct gcaggtccta gaagaagtgc tgggtgaccc tgagctgaca ggagagaagt tccgccagtg gaaggagcag aaccgggagc tgtactcaga gggcctgggg gcctggggag tggcacaggc tgaaggcagc tcccacatct tgacctctga ctccacagaa cagtcccccc actccctgcc ctctgaccct gaagagcact cccatctctg ccccctgacc tcagagagca gcctccgacc tcctgacctc tga. It is sometimes possible for the material contained within the vial of "CNKSR1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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