CD300A cdna clone
CD300A cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the CD300 glycoprotein family of cell surface proteins found on leukocytes involved in immune response signaling pathways. This gene is located on chromosome 17 in a cluster with all but one of the other family members. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Uniprot Description
MAIR-I: Inhibitory receptor which may contribute to the down- regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Belongs to the CD300 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Immunoglobulin superfamily
Chromosomal Location of Human Ortholog: 17q25.1
Cellular Component: membrane; plasma membrane
Molecular Function: phosphatidylethanolamine binding; phosphatidylserine binding; protein binding
Biological Process: negative regulation of B cell proliferation; negative regulation of B cell receptor signaling pathway; negative regulation of fibroblast proliferation; negative regulation of MAP kinase activity; negative regulation of mast cell activation during immune response; negative regulation of mast cell degranulation; negative regulation of NK T cell activation; negative regulation of phagocytosis, engulfment; positive regulation of phosphoprotein phosphatase activity; regulation of immune response; regulation of T cell receptor signaling pathway
Research Articles on CD300A
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Product Notes
The CD300A cd300a (Catalog #AAA1273771) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgtggctgc cttgggctct gttgcttctc tgggtcccag gatgttttgc tctgagcaaa tgcaggaccg tggcgggccc cgtgggggga tccctgagtg tgcagtgtcc ctatgagaag gaacacagga ccctcaacaa atactggtgc agaccaccac agattttcct atgtgacaag attgtggaga ccaaagggtc agcaggaaaa aggaacggcc gagtgtccat cagggacagt cctgcaaacc tcagcttcac agtgaccctg gagaatctca cagaggagga tgcaggcacc tactggtgtg gggtggatac accatggctc cgagactttc atgatcccgt tgtcgaggtt gaggtgtccg tgttcccggc atcaacgtca atgacacctg caagtatcac tgcggccaag acctcaacaa tcacaactgc atttccacct gtatcatcca ctaccctgtt tgcagtgggt gccacccaca gtgccagcat ccaggaggaa actgaggagg tggtgaactc acagctcccg ctgctcctct ccctgctggc attgttgctg cttctgttgg tgggggcctc cctgctagcc tggaggatgt ttcagaaatg gatcaaagct ggtgaccatt cagagctgtc ccagaacccc aagcaggctg ccacgcagag tgagctgcac tacgcaaatc tggagctgct gatgtggcct ctgcaggaaa agccagcacc accaagggag gtggaggtgg aatacagcac tgtggcctcc cccagggaag aacttcacta tgcctcggtg gtgtttgatt ctaacaccaa caggatagct gctcagaggc ctcgggagga ggaaccagat tcagattaca gtgtgataag gaagacatag. It is sometimes possible for the material contained within the vial of "CD300A, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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