BLK cdna clone
BLK cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010]
Uniprot Description
BLK: a nonreceptor tyrosine kinase of the Src family. Expressed predominantly in B lymphocytes
Protein type: Kinase, protein; EC 2.7.10.2; Protein kinase, tyrosine (non-receptor); Protein kinase, TK; TK group; Src family
Chromosomal Location of Human Ortholog: 8p23-p22
Cellular Component: extrinsic to internal side of plasma membrane
Molecular Function: non-membrane spanning protein tyrosine kinase activity; protein binding; protein-tyrosine kinase activity; receptor binding
Biological Process: B cell receptor signaling pathway; cell differentiation; cytoskeleton organization and biogenesis; innate immune response; negative regulation of apoptosis; positive regulation of insulin secretion; regulation of cell proliferation; regulation of phagocytosis; transmembrane receptor protein tyrosine kinase signaling pathway
Disease: Maturity-onset Diabetes Of The Young, Type 11
Research Articles on BLK
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Product Notes
The BLK blk (Catalog #AAA1267188) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggggctgg taagtagcaa aaagccggac aaggaaaagc cgatcaaaga gaaggacaag ggccaatgga gccccctgaa ggtcagcgcc caagacaagg acgccccgcc actgccgccc ctggttgtct tcaaccacct tactcctcca ccgcccgatg aacacctgga tgaagacaag catttcgtgg tggctctgta tgactacacc gctatgaatg atcgggacct gcagatgctg aagggggaga agctacaggt cctgaaggga actggagact ggtggctggc caggtcactc gtcacaggaa gagaaggcta tgtgcccagc aactttgtgg cccgagtgga gagcctggaa atggaaaggt ggttctttag atcacagggt cggaaggagg ctgagaggca gcttcttgct ccaatcaaca aggccggctc ctttcttatc agagagagtg aaaccaacaa aggtgccttc tccctgtctg tgaaggatgt caccacccag ggggagctga tcaagcacta taagatccgc tgcctggatg aagggggcta ctacatctcc ccccggatca ccttcccctc gctccaggcc ctggtgcagc actattctaa gaagggggat ggtctatgcc agaggctgac cctgccctgt gtgcgcccgg ccccgcagaa tccctgggcc caggatgaat gggagatccc ccggcagtct ctcaggctgg tcaggaaact cgggtctgga caattcggcg aagtctggat gggttactac aaaaacaaca tgaaggtggc cattaagacg ctgaaggagg gaaccatgtc tccagaagcc tttctgggtg aggccaacgt gatgaaggct ctgcagcacg agcggctggt ccgactctac gcagtggtca ccaaggagcc catctacatt gtcaccgagt acatggccag aggatgcctg ctggatttcc tgaagacaga tgaagggagc agattgtcac tcccaaggct gattgacatg tcggcgcaga ttgctgaagg gatggcatac attgagcgca tgaattccat ccaccgcgac ctgcgggcgg ccaacatcct ggtgtctgag gccttgtgct gcaaaattgc tgattttggc ttggctcgaa tcatcgacag tgaatacacg gcccaagagg gggccaagtt ccccatcaag tggacagccc cggaagccat ccacttcggg gtcttcacca tcaaagcaga cgtgtggtcg tttggagtcc tcctgatgga agttgtcact tatgggcggg tgccataccc agggatgagc aaccccgagg tcatccgcaa cctggagcgc ggctaccgca tgccgcgccc cgacacctgc ccgcccgagc tgtaccgcgg cgtcatcgcc gagtgctggc gcagccggcc cgaggagcgg cccaccttcg agttcctgca gtcggtgctg gaggacttct acacggccac cgagcggcag tacgagctgc agccctag. It is sometimes possible for the material contained within the vial of "BLK, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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