ARHGAP29 cdna clone
ARHGAP29 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
Rap1 is a small GTPase that, through effectors, regulates Rho GTPase signaling. These effectors- Rasip1, Radil, and the protein encoded by this gene- translocate to the cell membrane, where they form a multiprotein complex. This complex is necessary for Rap1-induced inhibition of Rho signaling. Defects in this gene may be a cause of nonsyndromic cleft lip with or without cleft palate. [provided by RefSeq, Jun 2016]
Uniprot Description
ARHGAP29: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs; GAPs, Rac/Rho
Chromosomal Location of Human Ortholog: 1p22.1
Cellular Component: cytoplasm; cytosol
Molecular Function: GTPase activator activity; PDZ domain binding
Biological Process: regulation of small GTPase mediated signal transduction; Rho protein signal transduction
Research Articles on ARHGAP29
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Product Notes
The ARHGAP29 arhgap29 (Catalog #AAA1274934) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgattgctc acaaacagaa aaagacaaag aaaaaacgtg cttgggcatc aggtcaactc tctactgata ttacaacttc tgaaatgggg ctcaagtcct taagttccaa ctctattttt gatccggatt acatcaagga gttggtgaat gatatcagga agttctccca catgttacta tatttgaaag aagccatatt ttcagactgt tttaaagaag ttattcatat acgtctagag gaactgctcc gtgttttaaa gtctataatg aataaacatc agaacctcaa ttctgttgat cttcaaaatg ctgcagaaat gctcactgca aaagtgaaag ctgtgaactt cacagaagtt aatgaagaaa acaaaaacga tctcttccag gaagtgtttt cttctattga aactttggca tttacctttg gaaatatcct tacaaacttc cttatgggag atgtaggcaa tgattcatta ttgcgactgc ctgtttctcg agaaactaag tcgtttgaaa atgtttctgt ggaatcagtg gactcatcca gtgaaaaagg aaatttttcc cctttagaac tagacaacgt gctgttaaag aacactgact ctatcgagct ggctttgtca tatgctaaaa cttggtcaaa atatactaag aacatagttt catgggttga aaaaaagctt aacttggaat tggagtccac tagaaatatg gtcaagttgg cagaggcaac tagaactaac attggaattc aggagttcat gccactgcag tctctgttta ctaatgctct tcttaatgat atagaaagca gtcacctttt acaacaaaca attgcagctc tccaggctaa caaatttgtg cagcctctac ttggaaggaa aaatgaaatg gaaaaacaaa ggaaagaaat aaaagagctt tggaaacagg agcaaaataa aatgcttgaa gcagagaatg ctctcaaaaa ggcaaaatta ttatgcatgc aacgtcaaga tgaatatgag aaagcaaagt cttccatgtt tcgtgcagaa gaggagcatc tgtcttcaag tggcggatta gcaaaaaatc tcaacaagca actagaaaaa aagcgaaggt tggaagagga ggctctccaa aaagtaacga tctttttctt ttttatttgc aagttgaatt ag. It is sometimes possible for the material contained within the vial of "ARHGAP29, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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