APBA3 cdna clone
APBA3 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease. [provided by RefSeq, Jul 2008]
Uniprot Description
APBA3: May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: perinuclear region of cytoplasm
Molecular Function: enzyme binding; enzyme inhibitor activity; protein binding
Biological Process: negative regulation of catalytic activity
Research Articles on APBA3
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Product Notes
The APBA3 apba3 (Catalog #AAA1270115) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGACTTCC CCACAATTTC CCGATCCCCT TCGGGGCCTC CAGCCATGGA CTTGGAGGGG CCCAGGGACA TTCTTGTGCC TTCGGAGGAC CTCACCCCTG ACAGCCAGTG GGACCCTATG CCAGGAGGCC CCGGCAGCCT CAGTCGGATG GAACTTGATG AGTCAAGCCT TCAGGAGCTG GTGCAGCAGT TTGAAGCTCT GCCAGGCGAT CTGGTGGGCC CATCCCCAGG TGGAGCCCCC TGTCCCCTAC ACATTGCCAC AGGCCATGGC CTGGCCTCCC AGGAGATTGC TGATGCCCAC GGGCTCCTGT CTGCCGAAGC TGGCCGGGAT GACCTGCTGG GCCTCTTGCA CTGCGAGGAA TGCCCGCCTT CCCAGACTGG TCCTGAAGAG CCTCTAGAGC CTGCCCCCCG ACTGTTGCAG CCCCCTGAGG ACCCAGATGA GGATTCTGAC TCCCCAGAAT GGGTGGAGGG GGCCTCTGCT GAGCAGGAGG GCAGCAGGAG CTCAAGCAGT TCCCCGGAAC CCTGGCTGGA GACGGTGCCT CTAGTCACAC CTGAAGAGCC ACCCGCTGGT GCCCAGAGCC CCGAGACCCT GGCTTCCTAC CCTGCCCCCC AGGAGGTGCC TGGTCCCTGT GACCATGAAG ACCTCCTGGA CGGTGTCATA TTTGGGGCCA GGTACCTGGG GTCCACCCAG CTGGTGTCGG AACGGAACCC GCCCACCAGC ACGCGCATGG CCCAGGCCCG GGAGGCCATG GACCGCGTCA AGGCCCCCGA TGGGGAGACC CAGCCCATGA CGGAGGTGGA CCTGTTCGTC TCCACCAAGA GGATCAAGGT CTTGACAGCG GACTCCCAGG AGGCCATGAT GGACCACGCC CTGCATACCA TCTCCTACAC AGCCGACATC GGCTGCGTGC TGGTGCTGAT GGCGCGGCGG CGGCTGGCAC GGAGGCCGGC ACCCCAGGAC CACGGCCGCC GCCTCTACAA GATGCTCTGC CACGTATTCT ACGCGGAGGA CGCCCAGCTC ATCGCCCAGG CCATTGGCCA GGCCTTCGCC GCCGCCTACA GCCAGTTCCT ACGGGAAAGC GGTATTGACC CCAGCCAGGT GGGCGTGCAC CCGAGCCCAG GCGCCTGCCA CCTCCATAAT GGGGACCTGG ACCACTTCTC CAACAGTGAC AACTGCCGGG AGGTGCACCT CGAGAAGCGG CGAGGGGAGG GCCTGGGCGT GGCCCTGGTG GAGTCGGGCT GGGGCTCCCT GCTGCCCACA GCCGTCATCG CCAACCTGCT GCACGGGGGG CCTGCTGAGC GCTCGGGGGC CCTCAGCATC GGGGACCGCC TGACCGCCAT CAACGGGACC AGCCTGGTGG GGCTGCCCCT GGCTGCGTGC CAGGCCGCTG TCCGCGAGAC GAAGTCGCAG ACGTCGGTGA CACTCAGCAT CGTCCACTGC CCTCCCGTCA CCACCGCCAT CATCCACCGG CCCCACGCCC GCGAGCAGCT GGGCTTCTGC GTGGAGGACG GCATCATCTG CAGCCTCCTC CGTGGTGGCA TCGCCGAGCG TGGGGGCATC CGCGTCGGCC ACCGCATCAT TGAGATCAAT GGGCAGAGTG TGGTGGCCAC GCCACACGCC CGCATCATCG AGCTGCTCAC CGAGGCCTAT GGCGAGGTGC ATATCAAGAC GATGCCAGCT GCCACATATC GCCTCCTTAC AGGCCAGGAG CAGCCCGTGT ACCTGTGA. It is sometimes possible for the material contained within the vial of "APBA3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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