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APBA3 cdna clone

APBA3 cDNA Clone

Gene Names
APBA3; X11L2; mint3; MGC:15815
Synonyms
APBA3; APBA3 cDNA Clone; APBA3 cdna clone
Ordering
For Research Use Only!
Sequence
ATGGACTTCCCCACAATTTCCCGATCCCCTTCGGGGCCTCCAGCCATGGACTTGGAGGGGCCCAGGGACATTCTTGTGCCTTCGGAGGACCTCACCCCTGACAGCCAGTGGGACCCTATGCCAGGAGGCCCCGGCAGCCTCAGTCGGATGGAACTTGATGAGTCAAGCCTTCAGGAGCTGGTGCAGCAGTTTGAAGCTCTGCCAGGCGATCTGGTGGGCCCATCCCCAGGTGGAGCCCCCTGTCCCCTACACATTGCCACAGGCCATGGCCTGGCCTCCCAGGAGATTGCTGATGCCCACGGGCTCCTGTCTGCCGAAGCTGGCCGGGATGACCTGCTGGGCCTCTTGCACTGCGAGGAATGCCCGCCTTCCCAGACTGGTCCTGAAGAGCCTCTAGAGCCTGCCCCCCGACTGTTGCAGCCCCCTGAGGACCCAGATGAGGATTCTGACTCCCCAGAATGGGTGGAGGGGGCCTCTGCTGAGCAGGAGGGCAGCAGGAGCTCAAGCAGTTCCCCGGAACCCTGGCTGGAGACGGTGCCTCTAGTCACACCTGAAGAGCCACCCGCTGGTGCCCAGAGCCCCGAGACCCTGGCTTCCTACCCTGCCCCCCAGGAGGTGCCTGGTCCCTGTGACCATGAAGACCTCCTGGACGGTGTCATATTTGGGGCCAGGTACCTGGGGTCCACCCAGCTGGTGTCGGAACGGAACCCGCCCACCAGCACGCGCATGGCCCAGGCCCGGGAGGCCATGGACCGCGTCAAGGCCCCCGATGGGGAGACCCAGCCCATGACGGAGGTGGACCTGTTCGTCTCCACCAAGAGGATCAAGGTCTTGACAGCGGACTCCCAGGAGGCCATGATGGACCACGCCCTGCATACCATCTCCTACACAGCCGACATCGGCTGCGTGCTGGTGCTGATGGCGCGGCGGCGGCTGGCACGGAGGCCGGCACCCCAGGACCACGGCCGCCGCCTCTACAAGATGCTCTGCCACGTATTCTACGCGGAGGACGCCCAGCTCATCGCCCAGGCCATTGGCCAGGCCTTCGCCGCCGCCTACAGCCAGTTCCTACGGGAAAGCGGTATTGACCCCAGCCAGGTGGGCGTGCACCCGAGCCCAGGCGCCTGCCACCTCCATAATGGGGACCTGGACCACTTCTCCAACAGTGACAACTGCCGGGAGGTGCACCTCGAGAAGCGGCGAGGGGAGGGCCTGGGCGTGGCCCTGGTGGAGTCGGGCTGGGGCTCCCTGCTGCCCACAGCCGTCATCGCCAACCTGCTGCACGGGGGGCCTGCTGAGCGCTCGGGGGCCCTCAGCATCGGGGACCGCCTGACCGCCATCAACGGGACCAGCCTGGTGGGGCTGCCCCTGGCTGCGTGCCAGGCCGCTGTCCGCGAGACGAAGTCGCAGACGTCGGTGACACTCAGCATCGTCCACTGCCCTCCCGTCACCACCGCCATCATCCACCGGCCCCACGCCCGCGAGCAGCTGGGCTTCTGCGTGGAGGACGGCATCATCTGCAGCCTCCTCCGTGGTGGCATCGCCGAGCGTGGGGGCATCCGCGTCGGCCACCGCATCATTGAGATCAATGGGCAGAGTGTGGTGGCCACGCCACACGCCCGCATCATCGAGCTGCTCACCGAGGCCTATGGCGAGGTGCATATCAAGACGATGCCAGCTGCCACATATCGCCTCCTTACAGGCCAGGAGCAGCCCGTGTACCTGTGA
Sequence Length
1728
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
61,454 Da
NCBI Official Full Name
Homo sapiens amyloid beta (A4) protein-binding, family A, member 3, mRNA
NCBI Official Synonym Full Names
amyloid beta precursor protein binding family A member 3
NCBI Official Symbol
APBA3
NCBI Official Synonym Symbols
X11L2; mint3; MGC:15815
NCBI Protein Information
amyloid beta A4 precursor protein-binding family A member 3
UniProt Protein Name
Amyloid beta A4 precursor protein-binding family A member 3
UniProt Gene Name
APBA3
UniProt Synonym Gene Names
MINT3; X11L2; Mint-3
UniProt Entry Name
APBA3_HUMAN

NCBI Description

The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease. [provided by RefSeq, Jul 2008]

Uniprot Description

APBA3: May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP. May enhance the activity of HIF1A in macrophages by inhibiting the activity of HIF1AN.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: perinuclear region of cytoplasm

Molecular Function: enzyme binding; enzyme inhibitor activity; protein binding

Biological Process: negative regulation of catalytic activity

Research Articles on APBA3

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Product Notes

The APBA3 apba3 (Catalog #AAA1270115) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGACTTCC CCACAATTTC CCGATCCCCT TCGGGGCCTC CAGCCATGGA CTTGGAGGGG CCCAGGGACA TTCTTGTGCC TTCGGAGGAC CTCACCCCTG ACAGCCAGTG GGACCCTATG CCAGGAGGCC CCGGCAGCCT CAGTCGGATG GAACTTGATG AGTCAAGCCT TCAGGAGCTG GTGCAGCAGT TTGAAGCTCT GCCAGGCGAT CTGGTGGGCC CATCCCCAGG TGGAGCCCCC TGTCCCCTAC ACATTGCCAC AGGCCATGGC CTGGCCTCCC AGGAGATTGC TGATGCCCAC GGGCTCCTGT CTGCCGAAGC TGGCCGGGAT GACCTGCTGG GCCTCTTGCA CTGCGAGGAA TGCCCGCCTT CCCAGACTGG TCCTGAAGAG CCTCTAGAGC CTGCCCCCCG ACTGTTGCAG CCCCCTGAGG ACCCAGATGA GGATTCTGAC TCCCCAGAAT GGGTGGAGGG GGCCTCTGCT GAGCAGGAGG GCAGCAGGAG CTCAAGCAGT TCCCCGGAAC CCTGGCTGGA GACGGTGCCT CTAGTCACAC CTGAAGAGCC ACCCGCTGGT GCCCAGAGCC CCGAGACCCT GGCTTCCTAC CCTGCCCCCC AGGAGGTGCC TGGTCCCTGT GACCATGAAG ACCTCCTGGA CGGTGTCATA TTTGGGGCCA GGTACCTGGG GTCCACCCAG CTGGTGTCGG AACGGAACCC GCCCACCAGC ACGCGCATGG CCCAGGCCCG GGAGGCCATG GACCGCGTCA AGGCCCCCGA TGGGGAGACC CAGCCCATGA CGGAGGTGGA CCTGTTCGTC TCCACCAAGA GGATCAAGGT CTTGACAGCG GACTCCCAGG AGGCCATGAT GGACCACGCC CTGCATACCA TCTCCTACAC AGCCGACATC GGCTGCGTGC TGGTGCTGAT GGCGCGGCGG CGGCTGGCAC GGAGGCCGGC ACCCCAGGAC CACGGCCGCC GCCTCTACAA GATGCTCTGC CACGTATTCT ACGCGGAGGA CGCCCAGCTC ATCGCCCAGG CCATTGGCCA GGCCTTCGCC GCCGCCTACA GCCAGTTCCT ACGGGAAAGC GGTATTGACC CCAGCCAGGT GGGCGTGCAC CCGAGCCCAG GCGCCTGCCA CCTCCATAAT GGGGACCTGG ACCACTTCTC CAACAGTGAC AACTGCCGGG AGGTGCACCT CGAGAAGCGG CGAGGGGAGG GCCTGGGCGT GGCCCTGGTG GAGTCGGGCT GGGGCTCCCT GCTGCCCACA GCCGTCATCG CCAACCTGCT GCACGGGGGG CCTGCTGAGC GCTCGGGGGC CCTCAGCATC GGGGACCGCC TGACCGCCAT CAACGGGACC AGCCTGGTGG GGCTGCCCCT GGCTGCGTGC CAGGCCGCTG TCCGCGAGAC GAAGTCGCAG ACGTCGGTGA CACTCAGCAT CGTCCACTGC CCTCCCGTCA CCACCGCCAT CATCCACCGG CCCCACGCCC GCGAGCAGCT GGGCTTCTGC GTGGAGGACG GCATCATCTG CAGCCTCCTC CGTGGTGGCA TCGCCGAGCG TGGGGGCATC CGCGTCGGCC ACCGCATCAT TGAGATCAAT GGGCAGAGTG TGGTGGCCAC GCCACACGCC CGCATCATCG AGCTGCTCAC CGAGGCCTAT GGCGAGGTGC ATATCAAGAC GATGCCAGCT GCCACATATC GCCTCCTTAC AGGCCAGGAG CAGCCCGTGT ACCTGTGA. It is sometimes possible for the material contained within the vial of "APBA3, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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