AP1M1 cdna clone
AP1M1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is the medium chain of the trans-Golgi network clathrin-associated protein complex AP-1. The other components of this complex are beta-prime-adaptin, gamma-adaptin, and the small chain AP1S1. This complex is located at the Golgi vesicle and links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
AP1M1: Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Belongs to the adaptor complexes medium subunit family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 19p13.12
Cellular Component: cytoplasmic vesicle membrane; cytosol; Golgi membrane; lysosomal membrane; membrane; trans-Golgi network membrane
Molecular Function: protein binding
Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; melanosome organization and biogenesis; regulation of defense response to virus by virus
Research Articles on AP1M1
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Product Notes
The AP1M1 ap1m1 (Catalog #AAA1271179) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgtccgcca gcgccgtcta cgtgctggac ctgaagggca aggtgctcat ctgccggaac taccgtggcg acgtggacat gtcagaggtg gagcacttca tgcccatcct gatggagaag gaggaggagg ggatgctgtc gcccatcctg gcccacgggg gggtccgttt catgtggatc aaacacaaca acctgtatct ggttgccaca tccaagaaga acgcgtgcgt gtcgctggtc ttttctttcc tctataaggt ggtgcaggtg ttttccgagt acttcaagga gctggaggag gagagcatcc gggacaactt tgttatcatc tacgagctgc tggacgagct catggacttc ggctaccccc agaccaccga cagcaagatc ctgcaggagt acatcactca ggaaggccac aagctggaaa caggggcccc gcggccacca gccaccgtca ccaacgcggt gtcctggcgg tccgaaggca tcaagtatcg gaagaatgag gtgttcttgg acgtcatcga gtctgtcaac ctcttggtca gcgccaacgg caatgtcctg cgcagcgaga tcgtgggctc catcaagatg cgagtcttcc tctcgggcat gcccgagctg cgcctgggcc tcaacgacaa ggtcctcttt gacaacacgg gccgcggcaa aagcaaatcc gtggagctgg aggatgtgaa gttccaccag tgtgtgcggc tatcacgctt cgagaatgac cgcaccatct ccttcatccc acccgacggc gagttcgagc tcatgtccta ccgtctcaac acccacgtca agcctttgat atggatcgag tcggtgatcg agaagcactc ccacagccgc atcgagtaca tgatcaaggc caaaagccag ttcaagcggc ggtcaacagc caacaacgtg gagatccaca ttcccgtgcc caatgatgcc gactcaccca agttcaagac gacggtgggg agcgttaagt gggtccccga gaacagcgag attgtgtggt ccatcaagtc cttcccgggc ggcaaggagt acctgatgcg ggcccacttc ggcctgccta gtgtggaggc cgaagacaag gagggcaagc ccccgatcag tgtcaagttc gagatccctt acttcactac ctccggcatc caggtgcgct acctgaagat cattgagaag agtgggtacc aggccctgcc ctgggtgcgt tatatcacgc agaatggaga ttaccagctc cggacccagt ga. It is sometimes possible for the material contained within the vial of "AP1M1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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