ANKHD1 cdna clone
ANKHD1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments. [provided by RefSeq, Sep 2010]
Uniprot Description
ANKHD1: May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases. Belongs to the mask family. 6 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis; RNA-binding
Chromosomal Location of Human Ortholog: 5q31.3
Cellular Component: cytoplasm; nucleoplasm
Molecular Function: protein binding
Biological Process: innate immune response
Research Articles on ANKHD1
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Product Notes
The ANKHD1 ankhd1 (Catalog #AAA1277751) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgctgactg atagcggagg cggcggcacc tcctttgagg aggacctgga ctctgtggct ccgcgatccg ccccagctgg ggcctcggag ccgcctccgc cgggaggggt cggtctgggg atccgcaccg tgaggctctt tggggaggcc gggccagcgt cgggagtcgg cagcagcggc ggcggcggca gcggcagcgg tacgggcgga ggggacgcgg cgctggattt caagttggcg gctgccgtgc tgaggaccgg gggtggaggt ggtgcctctg gcagtgacga ggacgaagtg tccgaggttg aatcatttat tttggaccaa gaagatctgg ataacccagt gcttaaaaca acatcagaga tattcttatc aagtactgca gaaggagcag acttacgcac tgtggatcca gagacacagg cacgactaga agcattgcta gaagcagcag cttttgcaga tcctgaggta ctccggagac tgacatcctc agttagttgt gcactggatg aagctgctgc tgcactgaca cggatgaaag cagaaaacag ccacaatgca ggacaagtgg acactcgcag tctagcagaa gcttgttcag atggggatgt taatgctgtt cgtaaattgc tagatgaagg cagaagtgta aatgaacata cagaagaagg agaaagcctg ctgtgtttgg cttgttcagc agggtattat gaattagcac aagtattgct tgctatgcat gctaatgttg aagatcgagg gaataaagga gacataactc ccctgatggc agcttccagt ggaggttact tagatattgt gaaattatta cttcttcatg atgctgatgt caactcccag tctgcaacag gaaacactgc gctaacttat gcatgtgctg gaggatttgt tgacattgtt aaagtgctcc ttaatgaagg tgcaaatata gaagatcata atgaaaatgg acatactccc ttaatggaag cagccagtgc aggtcatgtg gaagttgcaa gagttctttt agatcatggt gcaggcatca acactcattc taatgaattc aaagaaagtg ctctaacact tgcttgctac aaaggccatt tggatatggt tcgctttcta cttgaagctg gtgcagatca agagcacaaa acagatgaga tgcacactgc cttaatggag gcctgcatgg atggacatgt agaggtggca cgtttgcttt tggatagtgg tgctcaagtg aacatgcctg cagattcatt tgaatctcca ttgacgctag ctgcctgtgg aggacatgtt gaattggcag ctctacttat tgaaagggga gcaaatcttg aagaagttaa tgatgaagga tacactccct tgatggaagc tgcccgggaa ggacatgaag aaatggtggc actactctta gcacaaggag caaatataaa tgcccagaca gaagaaactc aagaaactgc tcttactttg gcttgctgtg gaggattttc tgaagttgca gactttctta ttaaggcagg ggctgatata gaacttggct gctccacacc tctgatggag gcatctcagg agggacacct ggaattggtt aaatatttgc tggcttctgg cgctaatgtg catgctacaa cagcaacagg agacacagcc ttaacctatg cttgtgaaaa tggacatacg gatgttgcag atgttttact tcaagcaggg gctgatttag acaagcagga ggacatgaag actattttgg agggcataga tccggccaag catcaggtga gggtggcctt tgatgcttgt aagctactac gtaaagaata g. It is sometimes possible for the material contained within the vial of "ANKHD1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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