ALDH1L2 cdna clone
ALDH1L2 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010]
Uniprot Description
ALDH1L2: a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010]
Protein type: Oxidoreductase; EC 1.5.1.6
Chromosomal Location of Human Ortholog: 12q23.3
Cellular Component: mitochondrial matrix; mitochondrion
Molecular Function: 4-trimethylammoniobutyraldehyde dehydrogenase activity; aldehyde dehydrogenase (NAD) activity; aminobutyraldehyde dehydrogenase activity; formyltetrahydrofolate dehydrogenase activity
Biological Process: folic acid metabolic process
Research Articles on ALDH1L2
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Product Notes
The ALDH1L2 aldh1l2 (Catalog #AAA1266851) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGTCACTT TCTATGGCTC GACATTACTG AATAGCTCTG TGCCTCCTGG AGAACCACTG GAAATTAAAG GTGCCAAGAA GCCTGGTCTC GTTACCAAAA ATGGACTTGT TCTTTTTGGT AACGATGGAA AAGCACTGAC GGTGAGAAAT CTGCAGTTTG AAGATGGAAA AATGATCCCT GCCTCTCAGT ACTTTTCAAC GGGTGAGACG TCAGTGGTAG AACTGACAGC TGAAGAGGTG AAAGTGGCAG AGACCATCAA GGTCATCTGG GCTGGAATTT TAAGCAATGT CCCCATTATT GAAGACTCAA CAGACTTCTT TAAATCTGGA GCAAGCTCAA TGGATGTTGC CAGGCTGGTT GAAGAGATCA GACAGAAATG TGGTGGGCTT CAGTTGCAGA ATGAAGATGT CTATATGGCC ACCAAGTTTG AAGGCTTTAT CCAAAAGGTC GTGAGGAAAC TGAGAGGAGA AGATCAAGAG GTGGAGCTGG TTGTAGATTA TATTTCAAAG GAGGTCAATG AAATCATGGT AAAAATGCCA TACCAGTGTT TCATAAATGG ACAGTTCACA GATGCAGACG ATGGAAAGAC TTACGACACT ATCAACCCAA CAGATGGATC TACAATATGC AAAGTATCCT ACGCTTCTTT GGCGGATGTT GATAAAGCAG TAGCAGCAGC AAAAGATGCT TTTGAAAACG GTGAATGGGG AAGAATGAAT GCAAGAGAAA GAGGAAGATT GATGTATAGA CTTGCAGACC TACTGGAAGA GAACCAAGAA GAGCTGGCAA CTATTGAAGC CCTTGATTCA GGGGCTGTCT ATACCTTGGC CCTGAAGACA CACATTGGAA TGTCTGTGCA AACATTCAGA TATTTTGCTG GCTGGTGCGA CAAAATTCAG GGTTCTACTA TTCCAATCAA CCAGGCCCGT CCAAATCGCA ATCTGACCTT CACCAAGAAA GAGCCACTCG GTGTCTGTGC CATTATTATT CCCTGGAACT ACCCGCTGAT GATGCTGGCA TGGAAGAGTG CTGCGTGTTT GGCAGCAGGC AATACCTTAG TGCTCAAGCC AGCACAGGTC ACGCCCTTGA CTGCTTTGAA GTTTGCAGAA CTGTCTGTGA AAGCAGGCTT TCCAAAGGGG GTCATCAACA TCATTCCAGG CTCAGGTGGC ATAGCAGGAC AACGTCTGTC TGAACATCCT GACATCCGCA AACTTGGTTT CACTGGATCC ACTCCTATTG GCAAACAGAT CATGAAGAGC TGTGCTGTTA GCAACTTGAA GAAAGTTTCC CTTGAGCTTG GTGGCAAGTC TCCACTTATA ATATTTAATG ACTGTGAACT TGACAAGGCT GTGCGAATGG GCATGGGAGC AGTATTTTTC AACAAAGGAG AGAACTGTAT TGCTGCTGGG CGGTTGTTCG TGGAAGAATC CATCCACGAC GAATTTGTGA CAAGAGTGAT CCACTGA. It is sometimes possible for the material contained within the vial of "ALDH1L2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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