AKAP4 cdna clone
AKAP4 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is localized to the sperm flagellum and may be involved in the regulation of sperm motility. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Uniprot Description
AKAP4: Major structural component of sperm fibrous sheath. Plays a role in sperm motility. Belongs to the AKAP110 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold; Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: Xp11.2
Cellular Component: cytoplasm; cytoskeleton; nucleus
Molecular Function: protein kinase A binding
Biological Process: cell motility; signal transduction; single fertilization; sperm motility
Research Articles on AKAP4
Similar Products
Product Notes
The AKAP4 akap4 (Catalog #AAA1276519) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgatggcgt actctgatac tacaatgatg tctgatgata ttgactggtt acgcagccac aggggtgtgt gcaaggtaga tctctacaac ccagaaggac agcaagatca ggaccggaaa gtgatatgct ttgtcgatgt gtccaccctg aatgtagaag ataaagatta caaggatgct gctagttcca gctcagaagg caacttaaac ctgggaagtc tggaagaaaa agagattatc gtgatcaagg acactgagaa gaaagaccag tctaagacag agggatctgt atgccttttc aaacaagctc cctctgatcc tgtaagtgtc ctcaactggc ttctcagtga tctccagaag tatgccttgg gtttccaaca tgcactgagc ccctcaacct ctacctgtaa acataaagta ggagacacag agggcgaata tcacagagca tcctctgaga actgctacag tgtctatgcc gatcaagtga acatagatta tttgatgaac agacctcaaa acctacgtct agaaatgaca gcagctaaaa acaccaacaa taatcaaagt ccttcagctc ctccagccaa acctcctagc actcagagag cagtcatttc ccctgatgga gaatgttcta tagatgacct ttccttctac gtcaaccgac tatcttctct ggtaatccag atggcccata aggaaatcaa ggagaagttg gaaggtaaaa gcaaatgcct tcatcattca atctgtccat cccctgggaa caaagagaga atcagtcccc gaactcctgc gagcaagatt gcttctgaaa tggcctatga agctgtggaa ctgacagctg cagaaatgcg tggcactgga gaggagtcca gggaaggtgg ccagaaaagc tttctatata gcgaattatc caacaagagc aaaagtggag acaaacagat gtcccagaga gagagcaaag aatttgcaga ttccatcagc aaggggctca tggtttatgc aaatcaggtg gcatctgaca tgatggtctc tctcatgaag accttgaaag tgcacagctc tgggaagcca attccagcat ctgtggtcct gaagagggtg ttgctaaggc acaccaagga gattgtgtcc gatttgattg attcttgcat gaagaacctg cataatatta ctggggtcct gatgactgac tcagactttg tctcagctgt caagagaaat ctgttcaacc agtggaaaca aaatgctaca gacatcatgg aggccatgct gaagcgcttg gtcagtgccc ttataggtga ggagaaggag actaagtctc agagtctgtc atatgcatct ttaaaagctg ggtcccatga tcccaaatgc aggaatcaga gtcttgaatt ctccaccatg aaagctgaaa tgaaagagag ggacaaaggc aaaatgaaat cagacccatg caagtcactg actagtgctg agaaagtcgg tgaacacatt ctcaaagagg gcctaaccat ctggaaccaa aagcaaggaa actcatgcaa ggtggctacc aaagcatgca gcaataaaga tgagaaagga gaaaagatca atgcttccac agattcactg gccaaggacc tgattgtctc tgcccttaag ctgatccagt accatctgac ccagcagact aagggcaaag atacatgtga agaagactgt cctggttcca ccatgggcta tatggctcag agtactcaat atgaaaagtg tggaggtggc caaagtgcca aagcactttc agtgaaacaa ctagaatctc acagagcccc tggaccatcc acctgtcaaa aggagaacca acacctggac tcccagaaaa tggatatgtc aaacatcgtt ctaatgctga ttcagaaact gcttaatgag aaccccttca aatgtgagga tccatgcgaa ggtgagaaca agtgttctga gcccagggca agcaaagcag cttccatgtc caacagatct gacaaagcgg aagaacaatg ccaggagcat caagaacttg actgtaccag tgggatgaag caagcgaacg ggcaatttat agataaacta gtagaatctg tgatgaagct ctgccttatc atggctaagt atagcaacga tggggcagcc cttgctgagt tggaagaaca agcagcctcg gcaaataagc ccaatttcag gggcaccaga tgcattcaca gtggtgcaat gccacagaac tatcaagact ctcttggaca tgaagtaatt gtcaataatc agtgctctac aaatagcttg cagaagcagc tccaggctgt cctgcagtgg attgcagcct cccagtttaa cgtgcccatg ctctacttca tgggagataa ggatggacaa ctggaaaagc ttcctcaggt ttcagctaaa gcagcagaga aggggtacag tgtaggaggt cttcttcaag aggtcatgaa gtttgccaag gaacggcaac cagatgaagc tgtgggaaag gtggccagga aacagttgct ggactggctg ctcgctaacc tgtga. It is sometimes possible for the material contained within the vial of "AKAP4, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.