ADH4 cdna clone
ADH4 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008]
Uniprot Description
ADH4: class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes. [provided by RefSeq, Jul 2008]
Protein type: Xenobiotic Metabolism - drug metabolism - cytochrome P450; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.1; Amino Acid Metabolism - tyrosine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Xenobiotic Metabolism - metabolism by cytochrome P450; Oxidoreductase; Lipid Metabolism - fatty acid
Chromosomal Location of Human Ortholog: 4q22
Cellular Component: cytosol
Molecular Function: alcohol dehydrogenase activity; alcohol dehydrogenase activity, zinc-dependent; all-trans retinal binding; benzaldehyde dehydrogenase activity; NAD binding; NADPH:quinone reductase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; retinol binding; retinol dehydrogenase activity; zinc ion binding
Biological Process: alcohol catabolic process; alcohol metabolic process; aldehyde metabolic process; ethanol oxidation; retinoid metabolic process; retinol metabolic process
Research Articles on ADH4
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Product Notes
The ADH4 adh4 (Catalog #AAA1271613) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgggcacca agggcaaagt tattaaatgc aaagcagcca tcgcctggga agcaggcaag cccctttgca ttgaagaggt tgaagtagct ccccccaagg ctcatgaagt tcgcattcag atcattgcta cctccctgtg ccatactgat gccactgtta tcgattctaa atttgagggc ctagctttcc cagtgatcgt tggccatgag gctgcaggta ttgtggaaag tattgggcca ggagtgacca acgtcaaacc aggtgacaaa gtaattccac tttatgcacc tctatgtaga aaatgcaagt tttgtctgag tccactcaca aatttgtgtg ggaaaatcag taatctcaaa agtcctgcta gtgatcaaca actaatggaa gacaaaacca gcaggtttac ctgcaaagga aaaccagttt accatttctt tggaaccagt acattctctc agtacactgt ggtgtcagat atcaatcttg ccaaaataga tgatgatgca aatttagaga gagtttgtct gcttggatgt gggttttcaa ctggctatgg ggctgcaatc aacaatgcca aggtcacccc tggttcgact tgtgctgtct ttggcctagg aggtgtgggt ctttctgctg taatgggttg taaagcagca ggagcttcca gaatcatagg tattgacatc aacagtgaga agtttgtgaa ggctaaagcc ctgggagcca ctgactgcct caatcctaga gacttacata aacctatcca ggaagttatc attgaattga ccaagggagg tgtggatttt gcccttgact gtgcaggtgg atctgaaacc atgaaagcag ccctggactg tacaaccgca ggctggggat catgtacttt cattggagta gctgctggta gcaaaggatt gactgttttt ccagaggagc taataatcgg ccgtactata aatggaacat tctttggtgg ttggaaaagt gtagattcta tcccaaagct ggtcactgac tataagaata agaaattcaa tctggatgca ctggtgaccc ataccctgcc ttttgacaaa atcagtgagg catttgacct aatgaaccaa ggaaaaagca tccgaacaat cctcatcttt tga. It is sometimes possible for the material contained within the vial of "ADH4, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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