Cyclin-dependent kinase 8 (Cdk8) Recombinant Protein | Cdk8 recombinant protein
Recombinant Aedes aegypti Cyclin-dependent kinase 8 (Cdk8), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Cyclin-dependent kinase 8 (Cdk8); Recombinant Aedes aegypti Cyclin-dependent kinase 8 (Cdk8); partial; Cdk8 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-501aa, full length protein
Sequence
MDYEFKMKTQQERAKVEDLFEYEGCKVGRGTYGHVYKAHRKESNDTKDYALKQIEGTGLSMSACREIALLRELKHPNVINLIRVFLSHTDRKVWLLFDYAEHDLWHIIKFHRAAKATKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIRKMPEHHTLTKDFKRSNYANCSLVKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDPYFSEDPMPTADVFAGCPIPYPKREFLTDEDQDDKGESKRQQQQQQQQQANQQAQQNQQQQANHQNQQQNQQQQANQQNQQSQQQQQQQQMQQQQQAQAGGMDHSAAKRVRMSGPNGQPGNGMNQQDYQVQQAQQAAAAAAAAQQQQQQQQQQQMMFNNQQQGGFQQRY
Sequence Length
501
Species
Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
58,257 Da
NCBI Official Full Name
cyclin-dependent kinase 8 isoform X1
NCBI Official Symbol
LOC5574480
NCBI Protein Information
cyclin-dependent kinase 8
UniProt Protein Name
Cyclin-dependent kinase 8
Protein Family
UniProt Gene Name
Cdk8
Uniprot Description
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex ().
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Product Notes
The Cdk8 cdk8 (Catalog #AAA1455974) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-501aa, full length protein. The amino acid sequence is listed below: MDYEFKMKTQ QERAKVEDLF EYEGCKVGRG TYGHVYKAHR KESNDTKDYA LKQIEGTGLS MSACREIALL RELKHPNVIN LIRVFLSHTD RKVWLLFDYA EHDLWHIIKF HRAAKATKKP VMVPKGMVKS LLYQILDGIH YLHSNWVLHR DLKPANILVM GEGNERGRVK IADMGFARLF NAPLKPLADL DPVVVTFWYR APELLLGARH YTKAIDIWAI GCIFAELLTS EPIFHCRQED IKTSNPYHHD QLDRIFNVMG FPQDKDWEDI RKMPEHHTLT KDFKRSNYAN CSLVKYMERH KIKPDSKAFH LLQKLLLMDP NKRITSEQAM QDPYFSEDPM PTADVFAGCP IPYPKREFLT DEDQDDKGES KRQQQQQQQQ QANQQAQQNQ QQQANHQNQQ QNQQQQANQQ NQQSQQQQQQ QQMQQQQQAQ AGGMDHSAAK RVRMSGPNGQ PGNGMNQQDY QVQQAQQAAA AAAAAQQQQQ QQQQQQMMFN NQQQGGFQQR Y. It is sometimes possible for the material contained within the vial of "Cyclin-dependent kinase 8 (Cdk8), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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