Cell division control protein 6 homolog (CDC6) Recombinant Protein | CDC6 recombinant protein

Recombinant Human Cell division control protein 6 homolog (CDC6)

Cat. Num. AAA1330436

• Gene Names: CDC6; CDC18L; HsCDC6; MGORS5; HsCDC18
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Cell division control protein 6 homolog (CDC6); Recombinant Human Cell division control protein 6 homolog (CDC6); CDC6 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-560, Full length protein
• Sequence: MPQTRSQAQATISFPKRKLSRALNKAKNSSDAKLEPTNVQTVTCSPRVKALPLSPRKRLGDDNLCNTPHLPPCSPPKQGKKENGPPHSHTLKGRRLVFDNQLTIKSPSKRELAKVHQNKILSSVRKSQEITTNSEQRCPLKKESACVRLFKQEGTCYQQAKLVLNTAVPDRLPAREREMDVIRNFLREHICGKKAGSLYLSGAPGTGKTACLSRILQDLKKELKGFKTIMLNCMSLRTAQAVFPAIAQEICQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPPYTRNQIVTILQDRLNQVSRDQVLDNAAVQFCARKVSAVSGDVRKALDVCRRAIEIVESDVKSQTILKPLSECKSPSEPLIPKRVGLIHISQVISEVDGNRMTLSQEGAQDSFPLQQKILVCSLMLLIRQLKIKEVTLGKLYEAYSKVCRKQQVAAVDQSECLSLSGLLEARGILGLKRNKETRLTKVFFKIEEKEIEHALKDKALIGNILATGLP
• Sequence Length: 560

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for CDC6 recombinant protein

This protein is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

NCBI and Uniprot Product Information

• NCBI GI #: 4502703
• NCBI GeneID: 990
• NCBI Accession #: NP_001245.1
• NCBI GenBank Nucleotide #: NM_001254.3
• UniProt Accession #: Q99741; Q8TB30
• Molecular Weight: 62,720 Da
• NCBI Official Full Name: cell division control protein 6 homolog
• NCBI Official Synonym Full Names: cell division cycle 6
• NCBI Official Symbol: CDC6
• NCBI Official Synonym Symbols: CDC18L; HsCDC6; MGORS5; HsCDC18
• NCBI Protein Information: cell division control protein 6 homolog
• UniProt Protein Name: Cell division control protein 6 homolog
• Protein Family: Cell division control protein
• UniProt Gene Name: CDC6
• UniProt Synonym Gene Names: CDC18L; HsCdc18; HsCDC6

NCBI Description

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]

Uniprot Description

Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.