Rat Cell division control protein 42 homolog ELISA Kit | Cdc42 elisa kit
Rat Cell division control protein 42 homolog ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
small GTPase; involved in formation of cellular asymmetry [RGD, Feb 2006]
Uniprot Description
CDC42: a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. Causes the formation of thin, actin-rich surface projections called filopodia. The oncoprotein Dbl specifically catalyzes the dissociation of GDP from this protein. Regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Interacts with DOCK9 which activates it by exchanging GDP for GTP. Interacts with PARD6A, PARD6B and PARD6G in a GTP-dependent manner. Part of a complex with PARD3, PARD6A or PARD6B and PRKCI or PRKCZ. Interacts with CDC42EP4.Alternative splicing of this gene results in at least two transcript variants.
Protein type: G protein, monomeric; G protein, monomeric, Rho; G protein; Motility/polarity/chemotaxis
Cellular Component: apical part of cell; cell projection; cell soma; cytoplasm; cytosol; filopodium; focal adhesion; Golgi membrane; intercellular junction; intracellular; membrane; microtubule organizing center; midbody; myelin sheath; neuron projection; plasma membrane; secretory granule; spindle midzone
Molecular Function: apolipoprotein A-I receptor binding; GTP binding; GTP-dependent protein binding; GTPase activity; identical protein binding; mitogen-activated protein kinase kinase kinase binding; protein binding; protein kinase binding; Rho GDP-dissociation inhibitor binding; thioesterase binding
Biological Process: actin cytoskeleton organization and biogenesis; actin filament bundle formation; actin filament organization; cell division; cell-cell adhesion; endocytosis; epidermis morphogenesis; establishment and/or maintenance of apical/basal cell polarity; establishment of cell polarity; establishment of Golgi localization; filopodium formation; Golgi organization and biogenesis; hair follicle morphogenesis; heart contraction; keratinization; multicellular organism growth; negative regulation of protein complex assembly; neuron fate determination; nuclear migration; nucleus localization; positive regulation of cell growth; positive regulation of cytokinesis; positive regulation of DNA replication; positive regulation of JNK cascade; positive regulation of MAPKKK cascade; positive regulation of metalloenzyme activity; positive regulation of neuron apoptosis; positive regulation of peptidyl-serine phosphorylation; positive regulation of phosphoinositide 3-kinase activity; positive regulation of protein amino acid phosphorylation; positive regulation of pseudopodium formation; positive regulation of synapse structural plasticity; protein transport; protein ubiquitination; regulation of attachment of spindle microtubules to kinetochore; regulation of exocytosis; regulation of filopodium formation; regulation of mitosis; regulation of protein catabolic process; regulation of protein heterodimerization activity; regulation of protein kinase activity; regulation of protein metabolic process; regulation of protein stability; response to glucose stimulus; small GTPase mediated signal transduction; sprouting angiogenesis; substantia nigra development; Wnt receptor signaling pathway through beta-catenin
Research Articles on Cdc42
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Product Notes
The Rat Cdc42 cdc42 (Catalog #AAA2880539) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2880539 ELISA Kit recognizes Rat Cdc42. It is sometimes possible for the material contained within the vial of "Cell division control protein 42 homolog, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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