SDS-Page
CD52 recombinant protein
CD52 Protein, Mouse, Recombinant (hFc Tag)
Gene Names
Cd52; B7; MB7; CLS1; B7-Ag; AI463198; CAMPATH-1
Purity
>95% as determined by SDS-PAGE
Synonyms
CD52; CD52 Protein; Mouse; Recombinant (hFc Tag); Mouse Cd52/CDw52 Protein (Fc Tag); AI463198 Protein; B7 Protein; B7-Ag Protein; CAMPATH-1 Protein; CLS1 Protein; MB7 Protein; CD52 molecule; CD52 recombinant protein
Host
HEK293 Cells
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met1-Lys46
Species
Mouse
Endotoxin
<1.0EU per ug protein as determined by the LAL method.
Predicted N Terminal
Gly 24
Tag
C-human IgG1-Fc
Protein Construction
A DNA sequence encoding the mouse Cd52 (NP_038734.1)(Met1-Lys46) was expressed with the Fc region of human IgG1 at the C-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
SDS-Page
SDS-Page
Related Product Information for CD52 recombinant protein
Background: CD52/CDW52 is a small glycosylphosphatidylinositol (GPI) anchored glycoprotein. It has a mature peptide comprising only 12 amino acids and is abundantly expressed on human lymphocytes. From the clinical point of view this protein is an important target for therapeutic interventions aimed at leukocyte depletion in hematological malignancies and post-transplant immunosuppression. CD52/CDW52 may play a role in carrying and orienting carbohydrate. It is an unusually good target for complement-mediated cell lysis.
Product Categories/Family for CD52 recombinant protein
References
Piccaluga PP, et al. (2007) Expression of CD52 in peripheral T-cell lymphoma. Haematologica. 92(4): 566-7.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
7,798 Da
NCBI Official Full Name
CAMPATH-1 antigen
NCBI Official Synonym Full Names
CD52 antigen
NCBI Official Symbol
Cd52
NCBI Official Synonym Symbols
B7; MB7; CLS1; B7-Ag; AI463198; CAMPATH-1
NCBI Protein Information
CAMPATH-1 antigen; lymphocyte differentiation antigen B7
UniProt Protein Name
CAMPATH-1 antigen
Protein Family
UniProt Gene Name
Cd52
UniProt Synonym Gene Names
Cdw52; Mb7
UniProt Entry Name
CD52_MOUSE
Uniprot Description
CD52: May play a role in carrying and orienting carbohydrate, as well as having a more specific role.
Protein type: Membrane protein, GPI anchor; Membrane protein, integral
Cellular Component: membrane; plasma membrane
Research Articles on CD52
Similar Products
Product Notes
The CD52 cd52 (Catalog #AAA8122947) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Lys46. It is sometimes possible for the material contained within the vial of "CD52, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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