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SDS-PAGE

CD302 / CLEC13A recombinant protein

Recombinant Mouse CD302 / CLEC13A Protein (His tag)

Gene Names
Cd302; AI159627; 1110055L24Rik
Purity
> 93 % as determined by SDS-PAGE
Synonyms
CD302 / CLEC13A; Recombinant Mouse CD302 / CLEC13A Protein (His tag); RP23-10L17.2; 1110055L24Rik; AI159627; CD302 / CLEC13A recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
> 93 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
228
Application Notes
The secreted recombinant mouse CD302 comprises 147 amino acids and has a calculated molecular mass of 17 kDa. As a result of glycosylation, the apparent molecular mass of rmCD302 is approximately 23 kDa in SDS-PAGE under reducing conditions.
Predicted N Terminal
Asp 21
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for CD302 / CLEC13A recombinant protein
Background: CD302/CLEC13A (C-type lectin domain family 13 member A), also known as C-type lectin receptor DCL-1, is a type I transmembrane C-type lectin DCL-1/CD302. DCL-1 protein was highly conserved among the human, mouse, and rat orthologs. DCL-1 ectodomain contains only one CRD, whereas other type I transmembrane C-type lectins contain more than one domain (e.g. selectins and MMR). DCL-1 CP contains several putative motifs, including a Tyr-based internalization, a cluster of acidic amino acids, and Ser and Tyr phosphorylation motifs, suggesting that DCL-1 CP mediates not only endocytosis and late endosome targeting but also signaling. DCL-1 may be another cell/matrix adhesion receptor integrated in cell adhesion complexes and that DCL-1 dysfunction may affect APC adhesion and migration, causing suppression of APC function.

Description: A DNA sequence encoding the extracellular domain of mouse CD302 isoform 2 (Q9DCG2-2) (Met 1-His 156) was fused with a polyhistidine tag at the C-terminus.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
24,313 Da
NCBI Official Full Name
CD302 antigen isoform a
NCBI Official Synonym Full Names
CD302 antigen
NCBI Official Symbol
Cd302
NCBI Official Synonym Symbols
AI159627; 1110055L24Rik
NCBI Protein Information
CD302 antigen
UniProt Protein Name
CD302 antigen
UniProt Gene Name
Cd302
UniProt Synonym Gene Names
Clec13a

Uniprot Description

CD302: Potential multifunctional C-type lectin receptor that may play roles in endocytosis and phagocytosis as well as in cell adhesion and migration. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2|2 C1.1

Cellular Component: cell cortex; filopodium; membrane

Biological Process: phagocytosis

Research Articles on CD302 / CLEC13A

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Product Notes

The CD302 / CLEC13A cd302 (Catalog #AAA2546835) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The secreted recombinant mouse CD302 comprises 147 amino acids and has a calculated molecular mass of 17 kDa. As a result of glycosylation, the apparent molecular mass of rmCD302 is approximately 23 kDa in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the CD302 / CLEC13A cd302 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD302 / CLEC13A, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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