CD300A recombinant protein
Recombinant Mouse CD300A Protein
Gene Names
Cd300a; Clm8; LMIR1; MMAC8; Pigr4; MAIR-I; mcpir1; MAIR-Ia; B230315M08Rik
Reactivity
Mouse
Applications
ELISA, Western Blot, SDS-Page
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Synonyms
CD300A; Recombinant Mouse CD300A Protein; CMRF35H; IGSF12; CMRF35-like molecule 8; CLM-8; CD300 antigen-like family member A; CMRF-35-H9; CMRF35-H9; CMRF35-H; IRC1/IRC2; Immunoglobulin superfamily member 12; IgSF12; Inhibitory receptor protein 60; IRp60; NK inhibitory receptor; CD300a; CD300A recombinant protein
Host
Human cells
Reactivity
Mouse
Purity/Purification
Greater than 95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 uM filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Sequence
LHGPSTMSGS VGESLSVSCR YEEKFKTKDK YWCRVSLKIL CKDIVKTSSS EEARSGRVTI RDHPDNLTFT VTYESLTLED ADTYMCAVDI SLFDGSLGFD KYFKIELSVV PSEDPVSSPG PTLETPVVST SLPTKGPALG SNTEGHREHD YSQGLRVDDI EGRMDEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSREEMTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGK
Sequence Length
318
Applicable Applications for CD300A recombinant protein
ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)
Endotoxin
Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Directions for Use
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Preparation and Storage
Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
Related Product Information for CD300A recombinant protein
Recombinant Mouse CD300A Protein is produced by our mammalian expression system and the target gene encoding Leu28-Arg183 is expressed with a Fc tag at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
CMRF35-like molecule 8 isoform 1
NCBI Official Synonym Full Names
CD300A molecule
NCBI Official Symbol
Cd300a
NCBI Official Synonym Symbols
Clm8; LMIR1; MMAC8; Pigr4; MAIR-I; mcpir1; MAIR-Ia; B230315M08Rik
NCBI Protein Information
CMRF35-like molecule 8
UniProt Protein Name
CMRF35-like molecule 8
Protein Family
UniProt Gene Name
Cd300a
UniProt Synonym Gene Names
Clm8; Lmir1; Mcpir1; CLM-8; MAIR-1; MAIR-I
UniProt Entry Name
CLM8_MOUSE
Uniprot Description
MAIR-I: Inhibitory receptor which may contribute to the down- regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Belongs to the CD300 family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Immunoglobulin superfamily; Membrane protein, integral
Cellular Component: membrane; plasma membrane
Molecular Function: phosphatase binding; phosphatidylethanolamine binding; phosphatidylserine binding; protein binding
Biological Process: negative regulation of B cell proliferation; negative regulation of B cell receptor signaling pathway; negative regulation of fibroblast proliferation; negative regulation of MAP kinase activity; negative regulation of mast cell activation during immune response; negative regulation of mast cell degranulation; negative regulation of NK T cell activation; negative regulation of phagocytosis, engulfment; negative regulation of serotonin secretion; positive regulation of phosphoprotein phosphatase activity; receptor-mediated endocytosis; regulation of T cell receptor signaling pathway; serotonin secretion by mast cell
Research Articles on CD300A
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Product Notes
The CD300A cd300a (Catalog #AAA8248711) is a Recombinant Protein produced from Human cells and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Mouse CD300A Protein reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD300A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS). Researchers should empirically determine the suitability of the CD300A cd300a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: LHGPSTMSGS VGESLSVSCR YEEKFKTKDK YWCRVSLKIL CKDIVKTSSS EEARSGRVTI RDHPDNLTFT VTYESLTLED ADTYMCAVDI SLFDGSLGFD KYFKIELSVV PSEDPVSSPG PTLETPVVST SLPTKGPALG SNTEGHREHD YSQGLRVDDI EGRMDEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSREEMTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGK. It is sometimes possible for the material contained within the vial of "CD300A, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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