T-cell surface glycoprotein CD3 zeta chain (CD247) Recombinant Protein | CD247 recombinant protein

Recombinant Sheep T-cell surface glycoprotein CD3 zeta chain (CD247)

• Gene Names: CD247; CD3Z
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: T-cell surface glycoprotein CD3 zeta chain (CD247); Recombinant Sheep T-cell surface glycoprotein CD3 zeta chain (CD247); Recombinant T-cell surface glycoprotein CD3 zeta chain (CD247); T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain CD_antigen= CD247; CD247 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 22-30
• Sequence: QSFGLLDPK
• Sequence Length: 166

• Species: Ovis aries (Sheep)
• Preparation and Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 57164263
• NCBI GeneID: 443436
• NCBI Accession #: NP_001009417.1
• NCBI GenBank Nucleotide #: NM_001009417.1
• UniProt Accession #: P29329
• Molecular Weight: 18,704 Da
• NCBI Official Full Name: T-cell surface glycoprotein CD3 zeta chain
• NCBI Official Symbol: CD247
• NCBI Official Synonym Symbols: CD3Z
• NCBI Protein Information: T-cell surface glycoprotein CD3 zeta chain; CD3 Zeta chain; T-cell receptor T3 zeta chain
• UniProt Protein Name: T-cell surface glycoprotein CD3 zeta chain
• Protein Family: T-cell surface glycoprotein
• UniProt Gene Name: CD247
• UniProt Synonym Gene Names: CD3Z
• UniProt Entry Name: CD3Z_SHEEP

Uniprot Description

Function: Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.

Subunit structure: The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.

Subcellular location: Membrane; Single-pass type I membrane protein.

Post-translational modification: Phosphorylated on Tyr residues after T-cell receptor triggering

By similarity.

Sequence similarities: Belongs to the CD3Z/FCER1G family.Contains 3 ITAM domains.