CD1D recombinant protein
Recombinant Human CD1D
Gene Names
CD1D; R3; CD1A; R3G1
Purity
Greater than 85.0% as determined by SDS-PAGE
Synonyms
CD1D; Recombinant Human CD1D; Antigen-presenting glycoprotein CD1d; R3G1; CD antigen: CD1d; Differentiation Antigen CD1-Alpha-3; T-Cell Surface Glycoprotein CD1d; Thymocyte Antigen CD1D; CD1A; R3; CD1d Molecule; CD1D Antigen; D Polypeptide; CD1d Antigen; HMC Class I; Antigen-Like Glycoprotein CD1D; Antigen-Presenting Glycoprotein CD1d; CD1D Human; CD1D Human Recombinant; CD1D recombinant protein
Host
Sf9, Insect cells
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE
Form/Format
Sterile filtered colorless solution
Protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol
Protein solution (0.25mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol
Sequence
EVPQRLFPLR CLQISSFANS SWTRTDGLAW LGELQTHSWS NDSDTVRSLK PWSQGTFSDQ QWETLQHIFR VYRSSFTRDV KEFAKMLRLS YPLELQVSAG CEVHPGNASN NFFHVAFQGK DILSFQGTSW EPTQEAPLWV NLAIQVLNQD KWTRETVQWL LNGTCPQFVS GLLESGKSELKKQVKPKAWL SRGPSPGPGR LLLVCHVSGF YPKPVWVKWM RGEQEQQGTQ PGDILPNADE TWYLRATLDV VAGEAAGLSC RVKHSSLEGQ DIVLYWGGSY TSLEHHHHHH.
Sequence Length
70
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at-20 degree C for longer periods of time.
For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles
For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles
Related Product Information for CD1D recombinant protein
Description: CD1D produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 290 amino acids (20-301 a.a.) and having a molecular mass of 32.9kDa (Molecular size on SDS-PAGE will appear at approximately 40-57kDa). CD1Dis expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Introduction: CD1D, also known as antigen-presenting glycoprotein CD1d, is a transmembrane glycoprotein which belongs to the CD1 family of glycolipid antigen-presenting MHC-like molecules. CD1d-presented lipid antigens activate a special class of T cells, familiar as natural killer T (NKT) cells, during the interaction with the T-cell receptor present on NKT membranes. Once activated, NKT cells rapidly produce Th1 &Th2 cytokines, usually represented by interleukin 4 production.
Introduction: CD1D, also known as antigen-presenting glycoprotein CD1d, is a transmembrane glycoprotein which belongs to the CD1 family of glycolipid antigen-presenting MHC-like molecules. CD1d-presented lipid antigens activate a special class of T cells, familiar as natural killer T (NKT) cells, during the interaction with the T-cell receptor present on NKT membranes. Once activated, NKT cells rapidly produce Th1 &Th2 cytokines, usually represented by interleukin 4 production.
Product Categories/Family for CD1D recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
37,717 Da
NCBI Official Full Name
CD1d, partial
NCBI Official Synonym Full Names
CD1d molecule
NCBI Official Symbol
CD1D
NCBI Official Synonym Symbols
R3; CD1A; R3G1
NCBI Protein Information
antigen-presenting glycoprotein CD1d
UniProt Protein Name
Antigen-presenting glycoprotein CD1d
Protein Family
UniProt Gene Name
CD1D
NCBI Description
This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
Uniprot Description
Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
Research Articles on CD1D
Similar Products
Product Notes
The CD1D cd1d (Catalog #AAA147280) is a Recombinant Protein produced from Sf9, Insect cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: EVPQRLFPLR CLQISSFANS SWTRTDGLAW LGELQTHSWS NDSDTVRSLK PWSQGTFSDQ QWETLQHIFR VYRSSFTRDV KEFAKMLRLS YPLELQVSAG CEVHPGNASN NFFHVAFQGK DILSFQGTSW EPTQEAPLWV NLAIQVLNQD KWTRETVQWL LNGTCPQFVS GLLESGKSEL KKQVKPKAWL SRGPSPGPGR LLLVCHVSGF YPKPVWVKWM RGEQEQQGTQ PGDILPNADE TWYLRATLDV VAGEAAGLSC RVKHSSLEGQ DIVLYWGGSY TSLEHHHHHH. It is sometimes possible for the material contained within the vial of "CD1D, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
