T-complex protein 1 subunit zeta (CCT6A) Recombinant Protein | CCT6A recombinant protein

Recombinant Human T-complex protein 1 subunit zeta (CCT6A)

Cat. Num. AAA956633

• Gene Names: CCT6A; CCT6; Cctz; HTR3; TCPZ; TCP20; MoDP-2; TTCP20; CCT-zeta; CCT-zeta-1; TCP-1-zeta
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: T-complex protein 1 subunit zeta (CCT6A); Recombinant Human T-complex protein 1 subunit zeta (CCT6A); T-complex protein 1 subunit zeta; TCP-1-zeta; Acute morphine dependence-related protein 2; CCT-zeta-1; HTR3; Tcp20; CCT6A recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 2-531aa; Full Length
• Sequence: AAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
• Sequence Length: 530

• Species: Homo sapiens (Human)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

SDS-PAGE

Related Product Information for CCT6A recombinant protein

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

NCBI and Uniprot Product Information

• NCBI GI #: 58331171
• NCBI GeneID: 908
• NCBI Accession #: NP_001009186.1
• NCBI GenBank Nucleotide #: NM_001009186.1
• UniProt Accession #: P40227; Q3KP28; Q75LP4; Q96S46; A6NCD2
• Molecular Weight: 61.9 kDa
• NCBI Official Full Name: T-complex protein 1 subunit zeta isoform b
• NCBI Official Synonym Full Names: chaperonin containing TCP1, subunit 6A (zeta 1)
• NCBI Official Symbol: CCT6A
• NCBI Official Synonym Symbols: CCT6; Cctz; HTR3; TCPZ; TCP20; MoDP-2; TTCP20; CCT-zeta; CCT-zeta-1; TCP-1-zeta
• NCBI Protein Information: T-complex protein 1 subunit zeta; histidine transport regulator 3; T-complex protein 1, zeta subunit; amino acid transport defect-complementing; chaperonin containing T-complex subunit 6; acute morphine dependence related protein 2; acute morphine dependence-related protein 2
• UniProt Protein Name: T-complex protein 1 subunit zeta
• Protein Family: T-complex protein
• UniProt Gene Name: CCT6A
• UniProt Synonym Gene Names: CCT6; CCTZ; TCP-1-zeta
• UniProt Entry Name: TCPZ_HUMAN

NCBI Description

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, several pseudogenes of this gene have been located. [provided by RefSeq, Jun 2010]

Uniprot Description

CCT-zeta: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. Belongs to the TCP-1 chaperonin family.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 7p11.2

Cellular Component: chaperonin-containing T-complex; microtubule; cytoplasm; acrosome; cytosol

Molecular Function: protein binding; unfolded protein binding; ATP binding

Biological Process: 'de novo' posttranslational protein folding; cellular protein metabolic process; protein folding; binding of sperm to zona pellucida