C-C chemokine receptor type 4 (Ccr4) Recombinant Protein | Ccr4 recombinant protein
Recombinant Mouse C-C chemokine receptor type 4 (Ccr4)
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
NCBI and Uniprot Product Information
Uniprot Description
CCR4: High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol- calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. Belongs to the G-protein coupled receptor 1 family.
Protein type: Motility/polarity/chemotaxis; GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass
Cellular Component: cell soma; external side of plasma membrane; integral to membrane; membrane; plasma membrane
Molecular Function: C-C chemokine receptor activity; chemokine receptor activity; G-protein coupled receptor activity; signal transducer activity
Biological Process: chemotaxis; G-protein coupled receptor protein signaling pathway; homeostasis of number of cells; immune response; inflammatory response; neuron migration; positive regulation of positive chemotaxis; signal transduction; tolerance induction
Research Articles on Ccr4
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Product Notes
The Ccr4 ccr4 (Catalog #AAA7011017) is a Recombinant Protein produced from Cell Free Expression and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-360aa; Full length protein. This is a recombinant transmembrane protein expressed in a cell-free expression system. Researchers should empirically determine the suitability of the Ccr4 ccr4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MNATEVTDTT QDETVYNSYY FYESMPKPCT KEGIKAFGEV FLPPLYSLVF LLGLFGNSVV VLVLFKYKRL KSMTDVYLLN LAISDLLFVL SLPFWGYYAA DQWVFGLGLC KIVSWMYLVG FYSGIFFIML MSIDRYLAIV HAVFSLKART LTYGVITSLI TWSVAVFASL PGLLFSTCYT EHNHTYCKTQ YSVNSTTWKV LSSLEINVLG LLIPLGIMLF CYSMIIRTLQ HCKNEKKNRA VRMIFAVVVL FLGFWTPYNV VLFLETLVEL EVLQDCTLER YLDYAIQATE TLAFIHCCLN PVIYFFLGEK FRKYITQLFR TCRGPLVLCK HCDFLQVYSA DMSSSSYTQS TVDHDFRDAL. It is sometimes possible for the material contained within the vial of "C-C chemokine receptor type 4 (Ccr4), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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