Cyclin-K (CCNK) Recombinant Protein | CCNK recombinant protein

Recombinant Human Cyclin-K (CCNK)

Cat. Num. AAA1140516

• Gene Names: CCNK; CPR4
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Cyclin-K (CCNK); Recombinant Human Cyclin-K (CCNK); CCNK recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-354aa; Full Length of Isoform 2
• Sequence: MKENKENSSPSVTSANLDHTKPCWYWDKKDLAHTPSQLEGLDPATEARYRREGARFIFDVGTRLGLHYDTLATGIIYFHRFYMFHSFKQFPRYVTGACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFDLQVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAGRLCKFEIQEWTSKPMYRRWWEQFVQDVPVDVLEDICHQILDLYSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPLILLQGWACRQPATHLLPSPLEDSLLCPRPFPHPACLQLGGWGGQPG

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for CCNK recombinant protein

This protein is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities.

NCBI and Uniprot Product Information

• NCBI GI #: 150417989
• NCBI GeneID: 8812
• NCBI Accession #: NP_001092872.1
• NCBI GenBank Nucleotide #: NM_001099402.1
• UniProt Accession #: O75909; Q59FT6; Q86U16; Q96B63; Q9NNY9
• Molecular Weight: 42.9 kDa
• NCBI Official Full Name: cyclin-K
• NCBI Official Synonym Full Names: cyclin K
• NCBI Official Symbol: CCNK
• NCBI Official Synonym Symbols: CPR4
• NCBI Protein Information: cyclin-K
• UniProt Protein Name: Cyclin-K
• Protein Family: Cyclin
• UniProt Gene Name: CCNK
• UniProt Synonym Gene Names: CPR4

NCBI Description

The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities. [provided by RefSeq, Jul 2008]

Uniprot Description

Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A).