CCL3L1 recombinant protein

Recombinant Pig CCL3L1

Cat. Num. AAA225412

• Gene Names: CCL3L1; LD78; 464.2; MIP1AP; SCYA3L; G0S19-2; SCYA3L1; D17S1718; LD78BETA; LD78-beta(1-70)
• Reactivity: Pig
• Applications: ELISA, Western Blot
• Purity: >95% by SDS PAGE analysis; Purified by ion-exchange chromatography
• Synonyms: CCL3L1; Recombinant Pig CCL3L1; CCL3L1 recombinant protein

• Host: Pichia pastoris
• Reactivity: Pig
• Purity/Purification: >95% by SDS PAGE analysis; Purified by ion-exchange chromatography
• Form/Format: Lyophilized in phosphate buffered saline with 10% Trahalose.
• Sequence Length: 93

• Applicable Applications for CCL3L1 recombinant protein: ELISA (EIA), Western Blot (WB)
• Reconstitution: Reconstitute with 20 ul sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. It is recommend that the vial is gently mixed after reconstitution.
• Preparation and Storage: Prior to reconstitution store at -20 degree C. After reconstitution store at -20 degree C.; Storage in frost-free freezers is not recommended. This product should be stored undiluted. Shelf Life: 12 months from date of despatch

ELISA (EIA)

(Pig CCL3L1 ELISA Recombinant Pig CCL3L1 detected using Rabbit anti Pig CCL3L1 as the capture reagent and Rabbit anti Pig CCL3L1:Biotin as the detection reagent followed by Streptavidin:HRP)

Related Product Information for CCL3L1 recombinant protein

Recombinant Pig CCL3L1 is a 7.8 kDa peptide corresponding to aa 24 - 93 of porcine CCL3L1.

CCL3L1 is a secreted chemokine belonging to the intercrine beta (chemokine CC) family and involved in the recruitment of lymphocytes and monocytes. CCL3L1 functions as a ligand for CCR5.

NCBI and Uniprot Product Information

• NCBI GI #: 27477072
• NCBI GeneID: 6349
• NCBI Accession #: NP_066286.1
• NCBI GenBank Nucleotide #: NM_021006.5
• UniProt Accession #: P16619; Q3B7A8; Q53YA5; Q96I68; A6NGK6; B2RUX4
• Molecular Weight: 7.8 kDa
• NCBI Official Full Name: C-C motif chemokine 3-like 1
• NCBI Official Synonym Full Names: C-C motif chemokine ligand 3 like 1
• NCBI Official Symbol: CCL3L1
• NCBI Official Synonym Symbols: LD78; 464.2; MIP1AP; SCYA3L; G0S19-2; SCYA3L1; D17S1718; LD78BETA; LD78-beta(1-70)
• NCBI Protein Information: C-C motif chemokine 3-like 1
• UniProt Protein Name: C-C motif chemokine 3-like 1
• Protein Family: C-C motif chemokine
• UniProt Gene Name: CCL3L1
• UniProt Synonym Gene Names: D17S1718; G0S19-2; SCYA3L1

NCBI Description

This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility. This record represents one of two copies that are present on the ALT_REF_LOCI_2 alternate haplotype of the GRCh38 human reference genome assembly. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Uniprot Description

Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5.